Loperamide
Functional Colonic Diseases, Bacillary Dysentery ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
Opioid Agonist
Controlled Drug Substance
No
loperamide
Summary
Loperamide is used to treat diarrhea, which is frequent, loose, or watery bowel movements. It is effective for both acute diarrhea, which is sudden and short-term, and chronic diarrhea, which is long-lasting. It helps by reducing the frequency of bowel movements and making stools less watery.
Loperamide works by slowing down gut movement, which reduces the frequency of bowel movements and makes stools less watery. It acts on the muscles in the intestines to decrease their activity, similar to how a brake slows down a car, providing relief from diarrhea symptoms.
The usual starting dose for adults is 4 mg initially, followed by 2 mg after each loose stool, not exceeding 16 mg per day. It can be taken with or without food. For children, dosing is based on weight and age, so follow your doctor's instructions.
Common side effects of Loperamide include constipation, dizziness, and nausea. These effects vary from person to person and are usually mild. If you experience severe or persistent symptoms, consult your doctor for further evaluation and guidance.
Loperamide can cause serious heart problems if taken in high doses. Do not exceed the recommended dose. It is not recommended for people with certain bowel conditions like ulcerative colitis, which is inflammation of the colon. Always consult your doctor before use.
Indications and Purpose
How does Loperamide work?
Loperamide works by slowing down the movement of the gut, which reduces the frequency of bowel movements and makes stools less watery. It acts on the muscles in the intestines to decrease their activity, similar to how a brake slows down a car. This helps control diarrhea and provides relief from symptoms.
Is Loperamide effective?
Loperamide is effective for treating diarrhea by slowing down gut movement, which reduces the frequency of bowel movements. It is commonly used for short-term relief of acute diarrhea. Clinical studies support its effectiveness in reducing diarrhea symptoms. Always use Loperamide as directed by your doctor for the best results.
What is Loperamide?
Loperamide is a medication used to treat diarrhea. It belongs to a class of drugs called antidiarrheals. Loperamide works by slowing down gut movement, which reduces the frequency of bowel movements and makes stools less watery. It is commonly used for short-term relief of acute diarrhea and can also be used for chronic diarrhea under a doctor's guidance.
Directions for Use
For how long do I take Loperamide?
Loperamide is usually used for short-term relief of acute diarrhea. You should take it until your symptoms improve, but do not exceed the recommended duration without consulting your doctor. If your symptoms persist or worsen, contact your doctor for further evaluation and guidance.
How do I dispose of Loperamide?
Dispose of unused Loperamide by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Loperamide?
Take Loperamide as directed by your doctor, usually after each loose stool, but do not exceed the recommended dose. It can be taken with or without food. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up on doses. Always follow your doctor's specific instructions regarding dosage and administration.
How long does it take for Loperamide to start working?
Loperamide usually starts working within 1 to 2 hours after taking it. You should notice a reduction in diarrhea symptoms, such as fewer and more solid bowel movements, shortly after taking the medication. If you don't see improvement within 48 hours, contact your doctor for further evaluation and guidance.
How should I store Loperamide?
Store Loperamide at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in the bathroom, where humidity can affect the medication. Always keep Loperamide out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Loperamide?
The usual starting dose of Loperamide for adults is 4 mg initially, followed by 2 mg after each loose stool. Do not exceed 16 mg per day. For children, dosing is based on weight and age, so follow your doctor's instructions. Elderly patients should be monitored carefully. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Loperamide with other prescription drugs?
Loperamide can interact with certain medications, increasing the risk of side effects. For example, it can interact with drugs that affect heart rhythm, like certain antibiotics and antifungals. Always inform your doctor about all medications you are taking to avoid potential interactions. Your doctor can provide guidance on safe use and monitor for any unexpected effects.
Can Loperamide be taken safely while breastfeeding?
Loperamide is generally considered safe to use while breastfeeding, as it is not significantly excreted into breast milk. However, always consult your doctor before using Loperamide while breastfeeding to ensure it is appropriate for your situation. Your doctor can provide guidance on safe use and monitor for any unexpected effects on your baby.
Can Loperamide be taken safely while pregnant?
Loperamide is generally considered safe during pregnancy, but you should only use it if clearly needed and directed by your doctor. There is limited evidence on its safety during pregnancy, so always consult your doctor to weigh the benefits and risks before using Loperamide while pregnant.
Does Loperamide have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Loperamide include constipation, dizziness, and nausea. Serious side effects, though rare, include severe allergic reactions and heart problems. If you experience any severe or unusual symptoms, seek medical attention immediately. Always inform your doctor about any new or worsening symptoms while taking Loperamide.
Does Loperamide have any safety warnings?
Loperamide has important safety warnings. It can cause serious heart problems if taken in high doses. Do not exceed the recommended dose. If you experience symptoms like fainting, rapid heartbeat, or irregular heartbeats, seek medical help immediately. Loperamide can also cause constipation, so use it as directed by your doctor. Always follow your doctor's advice and report any unusual symptoms.
Is it safe to drink alcohol while taking Loperamide?
It's best to avoid alcohol while taking Loperamide. Alcohol can increase the risk of side effects like dizziness and drowsiness. If you choose to drink, limit your alcohol intake and watch for any unusual symptoms. Talk with your doctor about alcohol use while taking Loperamide to get personalized advice.
Is it safe to exercise while taking Loperamide?
You can exercise while taking Loperamide, but be cautious. This medication can cause dizziness or drowsiness in some people. If you feel dizzy or lightheaded during exercise, slow down or stop and rest. Drink plenty of water to stay hydrated. Consult your doctor if you have concerns about exercising while taking Loperamide.
Is it safe to stop Loperamide?
Loperamide is usually used for short-term relief of diarrhea. You can stop taking it once your symptoms improve. However, if you stop too soon, your symptoms may return. Always follow your doctor's advice on how long to take Loperamide. If you have concerns about stopping the medication, discuss them with your doctor.
Is Loperamide addictive?
Loperamide is not considered addictive or habit-forming. It works by slowing down gut movement to reduce diarrhea. This mechanism doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, talk with your doctor.
Is Loperamide safe for the elderly?
Elderly individuals may be more sensitive to the effects of Loperamide, especially constipation. It's important to use the lowest effective dose and monitor for side effects. Always consult a doctor before using Loperamide in elderly patients to ensure it is safe and appropriate for their health condition.
What are the most common side effects of Loperamide?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Loperamide include constipation, dizziness, and nausea. These effects vary from person to person. If you notice new symptoms after starting Loperamide, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Loperamide?
Do not use Loperamide if you have a known allergy to it or its ingredients. It is not recommended for people with certain bowel conditions like ulcerative colitis, which is inflammation of the colon, or bacterial enterocolitis, which is an infection of the intestines. Always consult your doctor before using Loperamide if you have any medical conditions.
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