Levorphanol
Pain
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Opioid Agonist
Controlled Drug Substance
YES

levorphanol
Summary
Levorphanol is used to treat moderate to severe pain, which refers to intense discomfort that can interfere with daily activities. It is often prescribed for conditions like post-surgical pain, cancer pain, and chronic pain conditions, which are long-lasting pain issues.
Levorphanol works by binding to opioid receptors, which are parts of the nervous system that process pain signals. This action changes how your brain perceives pain, providing relief by making the pain less noticeable.
The usual starting dose of Levorphanol for adults is 2 mg every 6 to 8 hours as needed for pain. It is taken orally, which means by mouth, and the maximum recommended dose is typically 6 mg per dose.
Common side effects of Levorphanol include dizziness, which is a feeling of being unsteady, drowsiness, which is feeling sleepy, nausea, which is feeling sick to your stomach, and constipation, which is difficulty in passing stools.
Levorphanol can cause serious breathing problems, especially when starting or increasing the dose. It can be habit-forming, leading to misuse or addiction. It should not be used if you have severe breathing problems or a known allergy to it.
Indications and Purpose
How does Levorphanol work?
Levorphanol works by binding to opioid receptors in the brain and spinal cord, which are parts of the nervous system that process pain signals. This action changes how your brain perceives pain, providing relief. Think of it like turning down the volume on a loudspeaker, making the pain less noticeable. Levorphanol is effective for managing moderate to severe pain, helping improve your comfort and quality of life. Always follow your doctor's instructions for safe and effective use.
Is Levorphanol effective?
Levorphanol is effective for managing moderate to severe pain. It works by changing how your brain and nervous system respond to pain. Clinical studies support its effectiveness in providing pain relief. Patients using Levorphanol often report significant improvements in their pain levels. Always follow your doctor's instructions to ensure the medication works effectively for your condition.
What is Levorphanol?
Levorphanol is a medication used to treat moderate to severe pain. It belongs to the class of drugs called opioid analgesics, which work by changing how your brain and nervous system respond to pain. Levorphanol is effective for pain relief and is often used when other pain medications are not sufficient. It can be used alone or in combination with other therapies to manage pain. Always follow your doctor's instructions when using Levorphanol to ensure safe and effective pain management.
Directions for Use
For how long do I take Levorphanol?
Levorphanol is usually used for short-term treatment of acute pain. The duration of use depends on your specific pain condition and your doctor's recommendations. It's not typically used for long-term treatment due to the risk of dependence. Always follow your doctor's instructions regarding how long to take Levorphanol. If you have concerns about the duration of use, discuss them with your doctor. They can help ensure your pain is managed safely and effectively.
How do I dispose of Levorphanol?
Dispose of unused Levorphanol by taking it to a drug take-back program or collection site at a pharmacy or hospital. This ensures it doesn't harm people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. Always keep it out of reach of children and pets.
How do I take Levorphanol?
Take Levorphanol exactly as prescribed by your doctor. It's usually taken every 6 to 8 hours as needed for pain. You can take it with or without food. Do not crush or chew the tablets, as this can release the drug all at once, increasing the risk of side effects. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose. Do not double up on doses. Avoid alcohol while taking Levorphanol, as it can increase drowsiness and dizziness.
How long does it take for Levorphanol to start working?
Levorphanol starts working within 30 to 60 minutes after taking it. The full therapeutic effect is usually achieved within 1 to 2 hours. Individual factors like your metabolism and overall health can affect how quickly it works. Always take Levorphanol exactly as prescribed for the best results. If you have concerns about how long it takes to work, discuss them with your doctor. They can help ensure your pain is managed effectively.
How should I store Levorphanol?
Store Levorphanol at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Do not store it in humid places like bathrooms, as moisture can affect its effectiveness. Always keep Levorphanol out of reach of children and pets to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Levorphanol?
The usual starting dose of Levorphanol for adults is 2 mg every 6 to 8 hours as needed for pain. Your doctor may adjust the dose based on your response and pain control needs. The maximum recommended dose is typically 6 mg per dose. For elderly patients or those with certain health conditions, lower doses may be necessary. Always follow your doctor's specific dosing instructions to ensure safe and effective pain management.
Warnings and Precautions
Can I take Levorphanol with other prescription drugs?
Levorphanol can interact with other medications, increasing the risk of adverse effects. Major interactions include other central nervous system depressants like benzodiazepines, which can enhance drowsiness and respiratory depression. Moderate interactions include certain antidepressants, which can increase the risk of serotonin syndrome, a condition with symptoms like confusion and rapid heart rate. Always inform your doctor about all medications you are taking to avoid harmful interactions and ensure safe use of Levorphanol.
Can Levorphanol be taken safely while breastfeeding?
Levorphanol is not recommended while breastfeeding. It can pass into breast milk and may affect the nursing infant. Potential effects on the baby include drowsiness and difficulty breathing. We don't have much information about how Levorphanol affects milk supply. If you're taking Levorphanol and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can Levorphanol be taken safely while pregnant?
Levorphanol is not recommended during pregnancy unless absolutely necessary. There is limited evidence on its safety for pregnant women. Using Levorphanol during pregnancy can cause withdrawal symptoms in newborns, which is called neonatal abstinence syndrome. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your pain. They can help create a treatment plan that protects both you and your baby.
Does Levorphanol have adverse effects?
Adverse effects are unwanted reactions to a medication. Levorphanol can cause nausea, dizziness, and drowsiness, which are common adverse effects. Serious side effects include breathing problems and allergic reactions, which require immediate medical attention. If you experience any new or worsening symptoms while taking Levorphanol, contact your doctor. They can help determine if the symptoms are related to the medication and suggest appropriate actions to take.
Does Levorphanol have any safety warnings?
Yes, Levorphanol has important safety warnings. It can cause serious breathing problems, especially when starting the medication or increasing the dose. This risk is higher in older adults and those with lung problems. Levorphanol can also be habit-forming, leading to misuse or addiction. Taking it with alcohol or other sedatives increases the risk of severe side effects. Always follow your doctor's instructions and report any unusual symptoms. Not adhering to safety warnings can lead to life-threatening consequences.
Is it safe to drink alcohol while taking Levorphanol?
It's best to avoid alcohol while taking Levorphanol. Alcohol can increase the risk of serious side effects like drowsiness, dizziness, and breathing problems. These effects can be dangerous and require immediate medical attention. If you do choose to drink occasionally, limit how much alcohol you consume and watch for warning signs. Talk with your doctor about alcohol use while taking Levorphanol to get personalized advice based on your specific health situation.
Is it safe to exercise while taking Levorphanol?
You can exercise while taking Levorphanol, but be cautious. This medication can cause dizziness and drowsiness, which might affect your ability to exercise safely. Avoid strenuous activities or high-impact sports until you know how Levorphanol affects you. To exercise safely, start with light activities and gradually increase intensity. If you feel dizzy or unusually tired, stop exercising and rest. Talk with your doctor if you have concerns about your specific situation.
Is it safe to stop Levorphanol?
Stopping Levorphanol suddenly can cause withdrawal symptoms, such as restlessness, anxiety, and sweating. It's important to talk with your doctor before stopping the medication. They may suggest gradually reducing your dose to minimize withdrawal effects. Levorphanol is usually used for short-term pain relief, but if you need to stop, your doctor will help you do so safely. Always follow your doctor's advice to protect your health.
Is Levorphanol addictive?
Yes, Levorphanol can be addictive. It has the potential to cause physical and psychological dependence. This is because it affects brain chemistry, leading to cravings and a compulsion to take more. Warning signs of dependence include taking more than prescribed or feeling unable to stop. To prevent addiction, use Levorphanol exactly as prescribed and discuss any concerns with your doctor. They can help manage your pain safely and reduce the risk of dependence.
Is Levorphanol safe for the elderly?
Elderly individuals are more vulnerable to the safety risks of Levorphanol due to age-related changes in drug metabolism and increased sensitivity to side effects. Levorphanol can cause dizziness, drowsiness, and confusion, which are more common in older adults. These effects increase the risk of falls and injuries. It's important for elderly patients to use Levorphanol under close medical supervision, with careful dose adjustments to minimize risks.
What are the most common side effects of Levorphanol?
Side effects are unwanted reactions to a medication. Common side effects of Levorphanol include dizziness, drowsiness, nausea, and constipation. These effects vary from person to person. If you notice new symptoms after starting Levorphanol, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication. They can help determine if the side effects are related to Levorphanol and suggest ways to manage them.
Who should avoid taking Levorphanol?
Levorphanol should not be used if you have severe breathing problems or a known allergy to it. These are absolute contraindications. Relative contraindications include liver or kidney disease, where caution is needed, and the drug may be used only if benefits outweigh risks. Always consult your doctor about your medical history before starting Levorphanol to ensure it's safe for you.