Levomepromazine
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
No
Summary
Levomepromazine is used to treat schizophrenia, which is a mental disorder causing hallucinations and agitation, and severe pain. It helps manage symptoms by calming the brain's activity. It's also used for its sedative effects, which means it can help with sleep or relaxation in some cases.
Levomepromazine works by blocking dopamine receptors, which are parts of the brain that help control mood and perception. This action reduces symptoms like hallucinations and agitation, making it effective for treating conditions like schizophrenia and severe pain.
The usual starting dose for adults is 25 mg to 50 mg, taken one to three times daily, depending on the condition. It can be taken with or without food. Always follow your doctor's instructions for the correct dosage and administration.
Common side effects of levomepromazine include drowsiness, which means feeling very sleepy, dry mouth, and dizziness. These effects occur in more than 10% of people taking the medication. If you experience severe side effects, contact your doctor immediately.
Levomepromazine can cause drowsiness, affecting your ability to drive or operate machinery. Avoid alcohol, as it can increase side effects. It's not recommended for people with severe liver disease or those in a coma. Always consult your doctor about your medical history before starting levomepromazine.
Indications and Purpose
How does levomepromazine work?
Levomepromazine works by blocking dopamine receptors in the brain, which helps reduce symptoms like hallucinations and agitation. Think of it like turning down the volume on a loudspeaker, calming the brain's activity. This makes it effective for treating conditions like schizophrenia and severe pain. Always follow your doctor's instructions for safe and effective use.
Is levomepromazine effective?
Levomepromazine is effective for treating conditions like schizophrenia and severe pain. It works by blocking certain chemicals in the brain, which helps reduce symptoms like hallucinations and agitation. Clinical studies support its effectiveness in managing these conditions. Always follow your doctor's instructions to achieve the best results with levomepromazine.
What is levomepromazine?
Levomepromazine is an antipsychotic medication used to treat conditions like schizophrenia and severe pain. It works by blocking certain chemicals in the brain, which helps reduce symptoms like hallucinations and agitation. It's also used for its sedative effects in some cases. Always follow your doctor's instructions when using levomepromazine to ensure safe and effective treatment.
Directions for Use
For how long do I take levomepromazine?
Levomepromazine is usually used for long-term treatment of chronic conditions like schizophrenia. The duration depends on your response and any side effects. Your doctor will guide you on how long to take it. Don't stop taking levomepromazine without medical advice, as this could worsen your condition. Always follow your doctor's instructions for safe and effective use.
How do I dispose of levomepromazine?
Dispose of levomepromazine by taking it to a drug take-back program or collection site at a pharmacy or hospital. If that's not possible, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. This helps prevent harm to people and the environment.
How do I take levomepromazine?
Take levomepromazine as prescribed by your doctor. It's usually taken once or twice daily, depending on your condition. You can take it with or without food. If you have trouble swallowing pills, ask your doctor if it can be crushed. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose. Don't take two doses at once. Avoid alcohol while taking this medication, as it can increase side effects. Always follow your doctor's specific instructions.
How long does it take for levomepromazine to start working?
Levomepromazine starts working within a few hours, but it may take several days to weeks to achieve its full therapeutic effect. The time it takes to work can vary based on individual factors like your condition and overall health. Always take levomepromazine as prescribed and talk with your doctor if you have concerns about its effectiveness.
How should I store levomepromazine?
Store levomepromazine at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of levomepromazine?
The usual starting dose of levomepromazine for adults is typically 25 mg to 50 mg, taken one to three times daily, depending on the condition being treated. Your doctor may adjust the dose based on your response and any side effects. The maximum recommended dose varies, so follow your doctor's instructions. For elderly patients, lower doses may be used to reduce the risk of side effects. Always follow your doctor's specific dosing instructions.
Warnings and Precautions
Can I take levomepromazine with other prescription drugs?
Levomepromazine can interact with other medications, increasing the risk of side effects. For example, combining it with other sedatives can enhance drowsiness. It may also interact with medications that affect heart rhythm. Always inform your doctor about all the medications you're taking to avoid potential interactions. They can adjust your treatment plan to ensure safety and effectiveness.
Can levomepromazine be taken safely while breastfeeding?
Levomepromazine is not recommended while breastfeeding. It may pass into breast milk and affect the baby. We don't have much information on its effects on milk supply or the breastfed infant. If you're breastfeeding and need medication, talk with your doctor about safer options. They can help you choose a treatment that allows you to nurse safely.
Can levomepromazine be taken safely while pregnant?
Levomepromazine is not recommended during pregnancy unless absolutely necessary. Limited evidence is available on its safety, and it may pose risks to the unborn baby. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options for your condition. Your doctor can help create a plan that protects both you and your baby.
Does levomepromazine have adverse effects?
Adverse effects are unwanted reactions to a medication. Levomepromazine can cause drowsiness, dry mouth, and dizziness, which are common adverse effects. Serious side effects include low blood pressure and movement disorders. If you experience severe side effects, such as difficulty breathing or severe dizziness, seek medical attention immediately. Always inform your doctor about any new or worsening symptoms while taking levomepromazine.
Does levomepromazine have any safety warnings?
Yes, levomepromazine has important safety warnings. It can cause drowsiness, which may impair your ability to drive or operate machinery. It may also increase the risk of falls, especially in the elderly. Not adhering to these warnings can lead to accidents or injuries. Always follow your doctor's advice and report any unusual symptoms. If you experience severe side effects, seek medical attention immediately.
Is it safe to drink alcohol while taking levomepromazine?
It's best to avoid alcohol while taking levomepromazine. Alcohol can increase the sedative effects of the medication, leading to increased drowsiness and dizziness. This combination can impair your ability to perform tasks that require alertness, like driving. If you choose to drink, limit your intake and be aware of how your body reacts. Talk with your doctor for personalized advice.
Is it safe to exercise while taking levomepromazine?
You can exercise while taking levomepromazine, but be cautious. This medication can cause drowsiness and dizziness, which might affect your balance and coordination during physical activity. To exercise safely, start with light activities and see how your body responds. If you feel dizzy or unusually tired, stop and rest. Always talk with your doctor about your exercise plans while on levomepromazine.
Is it safe to stop levomepromazine?
Stopping levomepromazine suddenly can cause withdrawal symptoms like nausea, vomiting, and restlessness. It's usually used for long-term treatment of chronic conditions. If you need to stop, your doctor will likely suggest gradually reducing the dose to minimize withdrawal effects. Always talk with your doctor before stopping levomepromazine to ensure a safe transition.
Is levomepromazine addictive?
Levomepromazine is not considered addictive or habit-forming. It does not typically cause physical or psychological dependence. However, if you notice any unusual cravings or feel compelled to take more than prescribed, talk to your doctor. They can help address any concerns and ensure safe use of the medication.
Is levomepromazine safe for the elderly?
Elderly individuals are more vulnerable to the side effects of levomepromazine, such as drowsiness and low blood pressure. These can increase the risk of falls and other complications. It's important for elderly patients to be closely monitored by their doctor while taking this medication. Dose adjustments may be necessary to ensure safety and effectiveness.
What are the most common side effects of levomepromazine?
Side effects are unwanted reactions to a medication. Common side effects of levomepromazine include drowsiness, dry mouth, and dizziness. These occur in more than 10% of people taking the medication. If you experience new symptoms after starting levomepromazine, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking levomepromazine?
Levomepromazine should not be used if you have a known allergy to it or its ingredients. It's also contraindicated in people with severe liver disease or those in a coma. Use caution if you have heart problems or low blood pressure. Always consult your doctor about your medical history before starting levomepromazine to ensure it's safe for you.
