Levocetirizine + Montelukast

Find more information about this combination medication at the webpages for Levocetirizine and Montelukast

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Brand Name

Montair LC 5mg/10mg Tablet , Zincast Tablet 10s ... show more

Approved Treatment Indication:

Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis ... show more

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This medicine contains a combination of 2 drugs Levocetirizine and Montelukast.
Levocetirizine and Montelukast are both used to treat the same disease or symptom but work in different ways in the body.
Most doctors will advise making sure that each individual medicine is safe and effective before using a combination form.

Summary

What conditions are Montelukast and Levocetirizine used for?
Montelukast is primarily used to prevent asthma attacks and treat allergic rhinitis, which are allergies that cause symptoms like sneezing, runny nose, and itchy eyes. Levocetirizine is used to relieve symptoms of allergies such as runny nose, sneezing, and hives by blocking histamine, a substance in the body that causes allergic symptoms.
How do Montelukast and Levocetirizine work in the body?
Montelukast works by blocking substances in the body called leukotrienes, which cause asthma and allergy symptoms. Levocetirizine works by blocking histamine receptors, preventing the typical allergic response such as itching, sneezing, and runny nose.
What are the usual dosages and routes of administration of Montelukast and Levocetirizine?
The usual adult daily dose for Montelukast is 10 mg, typically taken in the evening. For Levocetirizine, the standard adult dose is 5 mg, also taken once daily in the evening. Both medications are taken orally.
What are the most commonly observed adverse effects of Montelukast and Levocetirizine?
Common side effects of Levocetirizine include drowsiness, dry mouth, and fatigue. Montelukast may cause side effects such as headache, abdominal pain, and upper respiratory infections. Both medications can cause drowsiness.
What are the important safety warnings and contraindications of Montelukast and Levocetirizine?
Montelukast carries warnings about potential neuropsychiatric events such as agitation and depression and should be used cautiously in patients with a history of mental health issues. Levocetirizine should not be used by individuals with severe kidney disease or those who have had allergic reactions to it or similar antihistamines.

Government Approvals

US(FDA), UK(BNF)

WHO Essential Medicine

Known Teratogen

Pharmaceutical Class

None

Controlled Drug Substance

Summary

What conditions are Montelukast and Levocetirizine used for?
Montelukast is primarily used to prevent asthma attacks and treat allergic rhinitis, which are allergies that cause symptoms like sneezing, runny nose, and itchy eyes. Levocetirizine is used to relieve symptoms of allergies such as runny nose, sneezing, and hives by blocking histamine, a substance in the body that causes allergic symptoms.
How do Montelukast and Levocetirizine work in the body?
Montelukast works by blocking substances in the body called leukotrienes, which cause asthma and allergy symptoms. Levocetirizine works by blocking histamine receptors, preventing the typical allergic response such as itching, sneezing, and runny nose.
What are the usual dosages and routes of administration of Montelukast and Levocetirizine?
The usual adult daily dose for Montelukast is 10 mg, typically taken in the evening. For Levocetirizine, the standard adult dose is 5 mg, also taken once daily in the evening. Both medications are taken orally.
What are the most commonly observed adverse effects of Montelukast and Levocetirizine?
Common side effects of Levocetirizine include drowsiness, dry mouth, and fatigue. Montelukast may cause side effects such as headache, abdominal pain, and upper respiratory infections. Both medications can cause drowsiness.
What are the important safety warnings and contraindications of Montelukast and Levocetirizine?
Montelukast carries warnings about potential neuropsychiatric events such as agitation and depression and should be used cautiously in patients with a history of mental health issues. Levocetirizine should not be used by individuals with severe kidney disease or those who have had allergic reactions to it or similar antihistamines.

Indications and Purpose

What is combination of Levocetirizine and Montelukast used for?

The combination of Levocetirizine and Montelukast is used to help relieve symptoms of allergic rhinitis, which is commonly known as hay fever. This includes symptoms like sneezing, runny or itchy nose, and itchy or watery eyes. Levocetirizine is an antihistamine that helps reduce allergy symptoms by blocking a substance in the body called histamine, which is produced during an allergic reaction. Montelukast is a leukotriene receptor antagonist that works by blocking substances called leukotrienes, which can cause allergy symptoms and inflammation. Together, these medications help manage and alleviate the discomfort associated with allergies.

What is combination of Montelukast and Levocetirizine used for?

Montelukast is indicated for the prevention and chronic treatment of asthma, as well as for the relief of symptoms of seasonal and perennial allergic rhinitis. Levocetirizine is used to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria, which includes conditions like hives. Both medications are used to manage allergy-related conditions, but Montelukast is specifically beneficial for asthma management, while Levocetirizine is more focused on alleviating allergy symptoms.

How does combination of Levocetirizine and Montelukast work?

Levocetirizine and Montelukast are medications often used together to help manage symptoms of allergies and asthma. Levocetirizine is an antihistamine, which means it works by blocking the action of histamine, a substance in the body that causes allergic symptoms like sneezing, itching, and runny nose. By preventing histamine from binding to its receptors, Levocetirizine helps reduce these symptoms. Montelukast, on the other hand, is a leukotriene receptor antagonist. Leukotrienes are chemicals in the body that are released during an allergic reaction and can cause inflammation, swelling, and constriction of airways. Montelukast works by blocking the action of leukotrienes, thereby reducing inflammation and helping to prevent asthma attacks and allergy symptoms. Together, these medications provide a more comprehensive approach to managing allergies and asthma by targeting different pathways involved in the allergic response.

How does combination of Montelukast and Levocetirizine work?

Montelukast works by blocking leukotriene receptors, which are involved in the inflammatory process that leads to asthma and allergy symptoms. This action helps reduce bronchoconstriction and inflammation in the airways. Levocetirizine, on the other hand, is an antihistamine that blocks histamine receptors, preventing the typical allergic response such as itching, sneezing, and runny nose. Both medications target different pathways in the allergic response, providing a comprehensive approach to managing symptoms.

How effective is combination of Levocetirizine and Montelukast?

The combination of Levocetirizine and Montelukast is often used to manage symptoms of allergic rhinitis and asthma. Levocetirizine is an antihistamine that helps reduce allergy symptoms like sneezing, runny nose, and itching by blocking histamine, a substance your body makes during an allergic reaction. Montelukast is a leukotriene receptor antagonist that helps prevent wheezing, difficulty breathing, and chest tightness by blocking leukotrienes, chemicals in the body that cause asthma and allergy symptoms. According to the NHS, this combination can be effective in reducing symptoms for people who suffer from both allergies and asthma, as it addresses multiple pathways involved in these conditions. However, the effectiveness can vary from person to person, and it is important to follow a healthcare provider's advice on its use. For more detailed information, you can refer to resources like the NHS or DailyMeds, which provide comprehensive details on these medications.

How effective is combination of Montelukast and Levocetirizine?

Clinical trials have demonstrated that Montelukast effectively reduces asthma symptoms and improves lung function, while also alleviating symptoms of allergic rhinitis. Levocetirizine has been shown to significantly reduce symptoms of allergic rhinitis and chronic urticaria, such as itching and hives. Both medications have been proven effective in their respective areas through randomized, placebo-controlled studies, highlighting their roles in managing allergy-related conditions. Their effectiveness is supported by patient-reported outcomes and clinical assessments.

How does one know if combination of Levocetirizine and Montelukast is working?

The combination of Levocetirizine and Montelukast is typically used to manage symptoms of allergies, such as sneezing, runny nose, and itchy or watery eyes, as well as to help with asthma symptoms. You can tell if this combination is working if you notice a reduction in these symptoms. For example, you might experience less sneezing, a decrease in nasal congestion, or improved breathing if you have asthma. According to the NHS, it may take a few days to notice the full effects of these medications. If your symptoms improve and you feel more comfortable, it is a good indication that the medication is effective. However, if your symptoms persist or worsen, it is important to consult with a healthcare professional for further advice. Always follow the dosage instructions provided by your healthcare provider and report any side effects you experience. For more detailed information, you can refer to resources like the NHS or DailyMeds.

How does one know if combination of Montelukast and Levocetirizine is working?

The benefit of Montelukast is assessed by the reduction in asthma symptoms such as wheezing, difficulty breathing, and the frequency of asthma attacks. For Levocetirizine, the benefit is measured by the relief of allergy symptoms like sneezing, runny nose, and itching. Both medications are evaluated based on their ability to improve quality of life by reducing the severity and frequency of symptoms associated with allergies and respiratory conditions. Patient-reported outcomes and clinical assessments are commonly used to gauge effectiveness.

Directions for Use

What is the usual dose of combination of Levocetirizine and Montelukast?

The usual dose for adults and children over 12 years old for the combination of Levocetirizine and Montelukast is typically one tablet taken once daily in the evening. This tablet usually contains 5 mg of Levocetirizine and 10 mg of Montelukast. However, it's important to follow the specific dosing instructions provided by a healthcare professional or the medication's packaging. Always consult with a doctor or pharmacist before starting any new medication.

What is the usual dose of combination of Montelukast and Levocetirizine?

The usual adult daily dose for Montelukast is 10 mg, typically taken in the evening. For Levocetirizine, the standard adult dose is 5 mg, also taken once daily in the evening. Both medications are designed for once-daily dosing, which simplifies the treatment regimen and enhances patient compliance. Montelukast is primarily used for asthma and allergic rhinitis, while Levocetirizine is used for allergic rhinitis and chronic urticaria. Despite their different primary uses, both medications help manage symptoms related to allergies.

How does one take combination of Levocetirizine and Montelukast?

Levocetirizine and Montelukast are often prescribed together to help manage symptoms of allergies and asthma. Levocetirizine is an antihistamine that helps reduce allergy symptoms like sneezing, runny nose, and itching. Montelukast is a leukotriene receptor antagonist that helps prevent wheezing and shortness of breath. When taking these medications together, it is important to follow your healthcare provider's instructions. Typically, Levocetirizine is taken once daily, usually in the evening, with or without food. Montelukast is also taken once daily, often in the evening, and can be taken with or without food as well. Always take the medications as prescribed and do not adjust the dosage without consulting your healthcare provider. If you have any questions or experience side effects, contact your healthcare provider for advice.

How does one take combination of Montelukast and Levocetirizine?

Montelukast can be taken with or without food, and it is usually recommended to take it in the evening. Levocetirizine should also be taken once daily in the evening, with or without food. There are no specific food restrictions for either medication, but patients should follow their healthcare provider's instructions. Both medications are designed for once-daily dosing, which helps maintain consistent blood levels and symptom control.

For how long is combination of Levocetirizine and Montelukast taken?

The duration for taking a combination of Levocetirizine and Montelukast can vary depending on the individual's condition and the advice of a healthcare professional. Generally, these medications are used to manage symptoms of allergies and asthma. Levocetirizine is an antihistamine that helps reduce allergy symptoms like sneezing and runny nose, while Montelukast is used to prevent wheezing and shortness of breath caused by asthma. According to the NHS, these medications are often taken daily, and the length of treatment can range from a few weeks to several months, depending on the severity of the symptoms and the individual's response to the treatment. It's important to follow the guidance of a healthcare provider, who will determine the appropriate duration based on the patient's specific needs.

For how long is combination of Montelukast and Levocetirizine taken?

Montelukast is typically used as a long-term treatment for asthma and allergic rhinitis, with patients often taking it daily for extended periods to manage chronic symptoms. Levocetirizine is also used for long-term management of allergies and chronic urticaria, with daily use recommended during allergy seasons or as needed for chronic conditions. Both medications are intended for ongoing use to maintain symptom control, but the duration may vary based on individual patient needs and response to treatment.

How long does it take for combination of Levocetirizine and Montelukast to work?

Levocetirizine and Montelukast are medications often used together to help manage allergy symptoms and asthma. Levocetirizine is an antihistamine that helps reduce allergy symptoms like sneezing and runny nose, while Montelukast is a leukotriene receptor antagonist that helps prevent asthma attacks and allergic reactions. According to the NHS, Levocetirizine usually starts to work within an hour of taking it, providing relief from allergy symptoms. Montelukast, on the other hand, may take a few days to show its full effect, as it works by reducing inflammation in the airways over time. Therefore, while you might notice some immediate relief from allergy symptoms with Levocetirizine, the full benefits of the combination with Montelukast might take a few days to become apparent.

How long does it take for combination of Montelukast and Levocetirizine to work?

Montelukast typically starts working within a few hours, but its full effect may take several days to be noticeable, especially for chronic conditions like asthma. Levocetirizine, on the other hand, begins to relieve allergy symptoms within 1 hour of ingestion. Both medicines are used to manage symptoms related to allergies and asthma, but they work through different mechanisms. Montelukast is a leukotriene receptor antagonist, while Levocetirizine is an antihistamine. Together, they provide a comprehensive approach to managing allergic reactions and respiratory symptoms.

How does one store combination of Levocetirizine and Montelukast?

The combination of Levocetirizine and Montelukast should be stored at room temperature, away from direct sunlight and moisture. It is important to keep the medication in its original packaging to protect it from light and humidity. Additionally, ensure that it is kept out of reach of children and pets to prevent accidental ingestion. Always check the packaging for specific storage instructions provided by the manufacturer.

How does one store combination of Montelukast and Levocetirizine?

Both Montelukast and Levocetirizine should be stored at room temperature, away from excess heat and moisture. They do not require refrigeration. It is important to keep these medications in their original containers, tightly closed, and out of reach of children. Proper storage ensures the medications maintain their effectiveness and safety over time.

Warnings and Precautions

Are there harms and risks from taking combination of Levocetirizine and Montelukast?

Levocetirizine and Montelukast are medications often used together to manage symptoms of allergies and asthma. Levocetirizine is an antihistamine that helps reduce allergy symptoms like sneezing and runny nose, while Montelukast is a leukotriene receptor antagonist that helps prevent asthma attacks and allergic reactions. According to the NHS and other trusted sources, taking these medications together is generally considered safe for most people. However, as with any medication, there can be side effects. Common side effects of Levocetirizine include drowsiness, dry mouth, and fatigue. Montelukast can cause side effects such as headache, stomach pain, and in rare cases, mood changes or allergic reactions. It's important to follow your healthcare provider's instructions and report any unusual symptoms or side effects. If you have concerns about taking these medications together, consult with your doctor or pharmacist for personalized advice.

Are there harms and risks from taking combination of Montelukast and Levocetirizine?

Common side effects of Montelukast include headache, stomach pain, and tiredness, while significant adverse effects can include neuropsychiatric events like agitation and depression. Levocetirizine commonly causes drowsiness, dry mouth, and fatigue, with serious side effects including allergic reactions like swelling and rash. Both medications can cause drowsiness, and patients should be cautious when driving or operating machinery. It's important for patients to report any unusual symptoms to their healthcare provider.

Can I take combination of Levocetirizine and Montelukast with other prescription drugs?

Levocetirizine and Montelukast are medications often used to manage allergies and asthma. Levocetirizine is an antihistamine that helps reduce allergy symptoms like sneezing and runny nose, while Montelukast is a leukotriene receptor antagonist that helps prevent asthma attacks and allergic reactions. Before combining these with other prescription drugs, it's important to consult with a healthcare professional. This is because drug interactions can occur, which might affect how well the medications work or increase the risk of side effects. For example, combining these drugs with certain sedatives or other antihistamines might increase drowsiness. Always inform your doctor about all the medications you are taking, including over-the-counter drugs and supplements, to ensure safe and effective treatment.

Can I take combination of Montelukast and Levocetirizine with other prescription drugs?

Montelukast has few significant drug interactions, but caution is advised when used with phenobarbital and rifampin, which can reduce its effectiveness. Levocetirizine may interact with alcohol and other central nervous system depressants, increasing drowsiness. Both medications should be used cautiously with other drugs that cause sedation. Patients should inform their healthcare provider of all medications they are taking to manage potential interactions effectively.

Can I take combination of Levocetirizine and Montelukast with vitamins or supplements?

Yes, you can generally take Levocetirizine and Montelukast with vitamins or supplements. However, it's always a good idea to check with your healthcare provider or pharmacist. They can ensure there are no specific interactions with the particular vitamins or supplements you are taking. Levocetirizine is an antihistamine used to relieve allergy symptoms, and Montelukast is used to prevent asthma symptoms and treat allergies. Both medications work differently from vitamins and supplements, which are typically used to support overall health.

Can I take combination of Montelukast and Levocetirizine with vitamins or supplements?

There are no well-documented significant interactions between Montelukast or Levocetirizine and vitamins or dietary supplements. However, patients should always inform their healthcare provider about all the supplements they are taking to avoid potential interactions. Both medications are generally safe to use with most vitamins and supplements, but individual responses can vary, and professional guidance is recommended.

Can I take combination of Levocetirizine and Montelukast if I am pregnant?

If you are pregnant, it is important to consult your healthcare provider before taking any medication, including Levocetirizine and Montelukast. These medications are used to treat allergies and asthma, but their safety during pregnancy is not fully established. Your doctor can help weigh the potential benefits and risks to determine the best course of action for you and your baby.

Can I take combination of Montelukast and Levocetirizine if I am pregnant?

Montelukast has not been associated with an increased risk of birth defects in available studies, making it a potential option during pregnancy when benefits outweigh risks. Levocetirizine, like its racemic form cetirizine, has not shown harmful effects in animal studies, but human data are limited. Both medications should be used during pregnancy only if clearly needed, and healthcare providers should be consulted to assess the risks and benefits. Close monitoring is advised if these medications are used during pregnancy.

Can I take combination of Levocetirizine and Montelukast while breastfeeding?

According to the NHS, Levocetirizine is an antihistamine used to relieve allergy symptoms, and Montelukast is a medication that helps prevent asthma symptoms. When it comes to breastfeeding, it's important to be cautious with any medication. The NHS suggests that Levocetirizine is generally considered safe to use while breastfeeding, as only small amounts pass into breast milk and it's unlikely to harm the baby. However, it's always best to consult with a healthcare provider before taking any medication while breastfeeding. Montelukast, according to the NLM, also passes into breast milk in small amounts. The effects on a breastfeeding infant are not well studied, so it's crucial to discuss with a healthcare provider to weigh the benefits and potential risks. In summary, while both medications are generally considered safe, it's important to consult with a healthcare professional to ensure they are appropriate for your specific situation while breastfeeding.

Can I take combination of Montelukast and Levocetirizine while breastfeeding?

Montelukast is considered safe during breastfeeding, as it is not known to be excreted in significant amounts in breast milk. Levocetirizine is likely excreted in breast milk, similar to its racemic form, cetirizine, and may cause drowsiness in the breastfed infant. Both medications should be used with caution during lactation, and healthcare providers should be consulted to weigh the benefits against potential risks. Monitoring the infant for any adverse effects is recommended.

Who should avoid taking combination of Levocetirizine and Montelukast?

According to trusted sources like the NHS and NLM, certain individuals should avoid taking the combination of Levocetirizine and Montelukast. These include: 1. **People with Allergies to the Drugs**: If you have a known allergy to Levocetirizine, Montelukast, or any of their ingredients, you should not take this combination. 2. **Individuals with Severe Kidney Problems**: Levocetirizine is processed by the kidneys, so those with severe kidney impairment should avoid it or use it with caution. 3. **Pregnant or Breastfeeding Women**: It's important to consult a healthcare provider before taking these medications if you are pregnant or breastfeeding, as the safety for the baby is not fully established. 4. **Children Under a Certain Age**: The combination may not be suitable for very young children. The specific age restrictions can vary, so it's best to consult a healthcare professional. 5. **People with Certain Medical Conditions**: If you have a history of mental health issues, such as depression or anxiety, you should discuss with your doctor, as Montelukast has been associated with mood changes in some cases. Always consult with a healthcare provider to ensure these medications are safe for your specific health conditions.

Who should avoid taking combination of Montelukast and Levocetirizine?

Montelukast carries a warning for potential neuropsychiatric events, including agitation and depression, and should be used with caution in patients with a history of mental health issues. Levocetirizine may cause drowsiness and should be used cautiously in activities requiring alertness. Both medications are contraindicated in patients with known hypersensitivity to their components. Patients should be aware of these warnings and report any concerning symptoms to their healthcare provider promptly.