Lacosamide

Partial Epilepsies , Tonic-Clonic Epilepsy ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

None

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Controlled Drug Substance

YES

Summary

  • Lacosamide is used to treat partial-onset seizures, which are seizures that start in one part of the brain, in people with epilepsy, which is a disorder that causes repeated seizures.

  • Lacosamide works by stabilizing electrical activity in the brain, which helps control seizures. It affects sodium channels, which are pathways that help transmit electrical signals in the brain, reducing abnormal activity that can lead to seizures.

  • The usual starting dose for adults is 50 mg taken twice daily, which means two times a day. The maximum recommended dose is 400 mg per day. Lacosamide is usually taken by mouth, with or without food.

  • Common side effects of Lacosamide include dizziness, which is a feeling of being unsteady, headache, which is pain in the head, and nausea, which is a feeling of sickness in the stomach.

  • Lacosamide can cause dizziness and coordination problems, which may affect your ability to drive. It may also affect heart rhythm, so inform your doctor if you have heart issues. Do not take it if you're allergic to it or its ingredients.

Indications and Purpose

How does Lacosamide work?

Lacosamide works by stabilizing electrical activity in the brain, which helps control seizures. It affects sodium channels in the brain, reducing the likelihood of abnormal electrical activity that can lead to seizures. This action helps manage epilepsy and reduce seizure frequency.

Is Lacosamide effective?

Lacosamide is effective in treating partial-onset seizures in people with epilepsy. Clinical studies show it reduces seizure frequency and improves seizure control. Always follow your doctor's instructions and attend regular check-ups to monitor the effectiveness of your treatment.

What is Lacosamide?

Lacosamide is a medication used to treat partial-onset seizures in people with epilepsy. It belongs to a class of drugs called anticonvulsants, which help control seizures by stabilizing electrical activity in the brain. Lacosamide can be used alone or with other medications to manage epilepsy.

Directions for Use

For how long do I take Lacosamide?

Lacosamide is usually a long-term medication for managing epilepsy. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Lacosamide treatment.

How do I dispose of Lacosamide?

Bring unused Lacosamide to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, take it out of its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.

How do I take Lacosamide?

Lacosamide is usually taken twice daily, with or without food. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions regarding your dosage and any dietary restrictions.

How long does it take for Lacosamide to start working?

Lacosamide begins working shortly after you take it, but it may take several weeks to notice a significant reduction in seizure frequency. The time it takes to achieve full therapeutic effect can vary based on individual factors like your overall health and response to the medication. Take it exactly as prescribed for the best results.

How should I store Lacosamide?

Store Lacosamide at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in humid places like bathrooms. Always keep Lacosamide out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.

What is the usual dose of Lacosamide?

The usual starting dose of Lacosamide for adults is 50 mg twice daily. Your doctor may adjust your dose based on your response and needs. The maximum recommended dose is 400 mg per day. Always follow your doctor's specific dosing instructions for your personal health needs.

Warnings and Precautions

Can I take Lacosamide with other prescription drugs?

Lacosamide can interact with other medications, increasing the risk of side effects or reducing effectiveness. It's important to inform your doctor about all the medicines you take, including over-the-counter drugs and supplements. Your doctor can help manage potential interactions and adjust your treatment plan as needed.

Can Lacosamide be taken safely while breastfeeding?

Lacosamide's safety during breastfeeding is not well-established. It's unclear if it passes into human breast milk. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest options for managing your condition. They can help you make an informed decision about your treatment.

Can Lacosamide be taken safely while pregnant?

The safety of Lacosamide during pregnancy is not well-established. Animal studies have shown some risks, but human data is limited. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. They can help create a treatment plan that protects both you and your baby.

Does Lacosamide have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Lacosamide include dizziness, headache, and nausea. Serious side effects can include heart rhythm problems. If you experience any new or worsening symptoms, contact your doctor immediately.

Does Lacosamide have any safety warnings?

Lacosamide has important safety warnings. It can cause dizziness and coordination problems, which may affect your ability to drive or operate machinery. It may also cause heart rhythm problems, so inform your doctor if you have a history of heart issues. Always follow your doctor's advice and report any unusual symptoms.

Is it safe to drink alcohol while taking Lacosamide?

It's best to avoid alcohol while taking Lacosamide. Alcohol can increase the risk of side effects like dizziness and drowsiness. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like increased dizziness or coordination problems. Talk with your doctor about alcohol use while taking Lacosamide.

Is it safe to exercise while taking Lacosamide?

You can exercise while taking Lacosamide, but be cautious. This medication can cause dizziness, which might affect your balance during physical activity. To exercise safely, start with light activities and gradually increase intensity. If you feel dizzy or lightheaded, stop exercising and rest. Talk with your doctor if you have concerns about your exercise routine.

Is it safe to stop Lacosamide?

Stopping Lacosamide suddenly can cause your condition to worsen. If you're taking it for seizures, stopping abruptly may increase seizure frequency. Always talk with your doctor before stopping Lacosamide. They might suggest gradually reducing your dose to prevent withdrawal symptoms and keep your condition under control.

Is Lacosamide addictive?

Lacosamide is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. However, always follow your doctor's instructions and discuss any concerns about medication dependence with them.

Is Lacosamide safe for the elderly?

Elderly individuals may be more sensitive to the side effects of Lacosamide, such as dizziness and coordination problems. These effects can increase the risk of falls. It's important for elderly patients to be closely monitored by their doctor while taking Lacosamide. Dose adjustments may be necessary to ensure safety.

What are the most common side effects of Lacosamide?

Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Lacosamide include dizziness, headache, and nausea. These effects vary from person to person. If you notice new symptoms after starting Lacosamide, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking Lacosamide?

Do not take Lacosamide if you're allergic to it or its ingredients. It should be used with caution in people with heart problems, as it can affect heart rhythm. Always consult your doctor about any concerns and inform them of your medical history before starting Lacosamide.