Insulin Glargine

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Brand Name

Lantus 100IU/ml Solution for Injection , Basalog 100IU/ml Refill Cartridge ... show more

Approved Treatment Indication:

Type 2 Diabetes Mellitus, Hyperglycemia ... show more

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What conditions insulin glargine is used for
Insulin glargine is used to manage blood sugar levels in people with diabetes, which is a condition where the body cannot properly process sugar. It is effective for both type 1 diabetes, where the body doesn't produce insulin, and type 2 diabetes, where the body doesn't use insulin properly.
How insulin glargine works in the body
Insulin glargine works by providing a steady release of insulin, which is a hormone that helps regulate blood sugar levels. It mimics the body's natural insulin production, helping to lower blood sugar levels throughout the day and night.
The usual dosages and routes of administration of insulin glargine
Insulin glargine is usually taken once daily, at the same time each day, to help manage blood sugar levels. It should be injected under the skin, not into a vein or muscle. The dose varies based on individual needs and blood sugar levels.
The most commonly observed adverse effects of insulin glargine
Common adverse effects of insulin glargine include low blood sugar, which is called hypoglycemia, and injection site reactions like redness or swelling. Severe hypoglycemia is a serious side effect that requires immediate treatment.
Important safety warnings and contraindications of insulin glargine
Insulin glargine can cause low blood sugar, especially if you skip meals or exercise more than usual. Symptoms include dizziness and confusion. It should not be used if you are allergic to it or any of its ingredients. Always inform your doctor of your medical history.

Government Approvals

US(FDA)

WHO Essential Medicine

Known Teratogen

Pharmaceutical Class

Insulin Analog

Controlled Drug Substance

Summary

What conditions insulin glargine is used for
Insulin glargine is used to manage blood sugar levels in people with diabetes, which is a condition where the body cannot properly process sugar. It is effective for both type 1 diabetes, where the body doesn't produce insulin, and type 2 diabetes, where the body doesn't use insulin properly.
How insulin glargine works in the body
Insulin glargine works by providing a steady release of insulin, which is a hormone that helps regulate blood sugar levels. It mimics the body's natural insulin production, helping to lower blood sugar levels throughout the day and night.
The usual dosages and routes of administration of insulin glargine
Insulin glargine is usually taken once daily, at the same time each day, to help manage blood sugar levels. It should be injected under the skin, not into a vein or muscle. The dose varies based on individual needs and blood sugar levels.
The most commonly observed adverse effects of insulin glargine
Common adverse effects of insulin glargine include low blood sugar, which is called hypoglycemia, and injection site reactions like redness or swelling. Severe hypoglycemia is a serious side effect that requires immediate treatment.
Important safety warnings and contraindications of insulin glargine
Insulin glargine can cause low blood sugar, especially if you skip meals or exercise more than usual. Symptoms include dizziness and confusion. It should not be used if you are allergic to it or any of its ingredients. Always inform your doctor of your medical history.

Indications and Purpose

How does insulin glargine work?

Insulin glargine works by providing a steady release of insulin, which is a hormone that helps regulate blood sugar levels. It mimics the body's natural insulin production, helping to lower blood sugar levels throughout the day and night. This long-acting insulin is absorbed slowly, providing a consistent effect without peaks and troughs. It is used to manage diabetes by maintaining stable blood sugar levels and reducing the risk of complications.

Is insulin glargine effective?

Yes, insulin glargine is effective for managing blood sugar levels in people with diabetes. It provides a steady release of insulin to help control blood sugar throughout the day and night. Clinical studies show that insulin glargine effectively lowers blood sugar levels and reduces the risk of diabetes-related complications. Always follow your doctor's instructions and monitor your blood sugar regularly to ensure the medication is working for you.

What is insulin glargine?

Insulin glargine is a long-acting insulin used to manage blood sugar levels in people with diabetes. It belongs to the insulin class of medications and works by providing a steady release of insulin to help control blood sugar throughout the day and night. Insulin glargine is primarily used to treat type 1 and type 2 diabetes and is often used alongside other diabetes medications and lifestyle changes.

Directions for Use

For how long do I take insulin glargine?

Insulin glargine is usually a long-term medication for managing diabetes. You'll typically take it every day as part of your diabetes treatment plan. The duration of use depends on your individual health needs and how well your blood sugar is controlled. Always follow your doctor's instructions and discuss any concerns about your treatment plan with them.

How do I dispose of insulin glargine?

Dispose of unused insulin glargine by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options aren't available, you can throw it away at home. Remove it from its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it in the trash. This helps prevent harm to people and the environment.

How do I take insulin glargine?

Insulin glargine is usually taken once daily, at the same time each day, to help manage blood sugar levels. It should be injected under the skin, not into a vein or muscle. You can take it with or without food. If you miss a dose, take it as soon as you remember, but do not double up on doses. Always follow your doctor's specific instructions on how to use insulin glargine.

How long does it take for insulin glargine to start working?

Insulin glargine starts working within a few hours after injection and provides a steady release of insulin for up to 24 hours. It helps maintain stable blood sugar levels throughout the day and night. The full therapeutic effect may take a few days to become apparent. Individual factors like diet, exercise, and overall health can affect how quickly insulin glargine works. Always follow your doctor's instructions for best results.

How should I store insulin glargine?

Store insulin glargine in the refrigerator at a temperature between 36°F and 46°F. Once opened, you can keep it at room temperature, but it should be used within 28 days. Keep it away from direct heat and light. Do not freeze insulin glargine, and discard it if it has been frozen. Always check the expiration date and properly dispose of any unused or expired medication.

What is the usual dose of insulin glargine?

The usual starting dose of insulin glargine for adults varies based on individual needs and blood sugar levels. It's typically administered once daily. Your doctor will adjust the dose as needed to achieve optimal blood sugar control. There is no fixed maximum dose, as it depends on your specific health needs. Always follow your doctor's dosing instructions and report any concerns.

Warnings and Precautions

Can insulin glargine be taken safely while breastfeeding?

Insulin glargine is generally considered safe to use while breastfeeding. It does not pass into breast milk in significant amounts and is unlikely to affect the breastfed infant. However, always discuss your treatment plan with your doctor if you are breastfeeding. They can provide guidance on managing your diabetes while ensuring the safety of your baby.

Can insulin glargine be taken safely while pregnant?

Insulin glargine is generally considered safe to use during pregnancy to manage diabetes. Maintaining good blood sugar control is important for the health of both mother and baby. However, always discuss your treatment plan with your doctor if you are pregnant or planning to become pregnant. They can provide guidance on the safest way to manage your blood sugar during this time.

Can I take insulin glargine with other prescription drugs?

Insulin glargine can interact with other medications that affect blood sugar levels, such as oral diabetes medications and certain blood pressure drugs. These interactions can increase the risk of low blood sugar, which is called hypoglycemia. Always inform your doctor about all medications you are taking to avoid potential interactions. They can adjust your treatment plan to ensure safe and effective use of insulin glargine.

Does insulin glargine have adverse effects?

Adverse effects are unwanted reactions to a medication. With insulin glargine, common adverse effects include low blood sugar, which is called hypoglycemia, and injection site reactions like redness or swelling. Severe hypoglycemia is a serious side effect that requires immediate treatment. If you experience any new or worsening symptoms, contact your doctor. They can help determine if these are related to insulin glargine and advise on appropriate actions.

Does insulin glargine have any safety warnings?

Yes, insulin glargine has safety warnings. It can cause low blood sugar, which is called hypoglycemia, especially if you skip meals or exercise more than usual. Symptoms include dizziness, sweating, and confusion. Severe hypoglycemia can lead to unconsciousness. Always carry a source of sugar, like glucose tablets, to treat low blood sugar. Inform your doctor if you experience frequent low blood sugar episodes.

Is insulin glargine addictive?

Insulin glargine is not addictive. It does not have habit-forming potential and does not cause physical or psychological dependence. Insulin glargine works by helping your body manage blood sugar levels, and it does not affect brain chemistry in a way that could lead to addiction. You can stop using it without experiencing withdrawal symptoms, but always consult your doctor before making changes to your medication.

Is insulin glargine safe for the elderly?

Insulin glargine is generally safe for elderly patients, but they may be more sensitive to its effects, especially the risk of low blood sugar, which is called hypoglycemia. Regular monitoring of blood sugar levels is important. Elderly patients should also be aware of potential injection site reactions. Always consult with a doctor to ensure insulin glargine is used safely and effectively in older adults.

Is it safe to drink alcohol while taking insulin glargine?

It's best to limit alcohol while taking insulin glargine. Alcohol can affect blood sugar levels, increasing the risk of low blood sugar, which is called hypoglycemia. Symptoms include dizziness, confusion, and fainting. If you choose to drink, do so in moderation and monitor your blood sugar closely. Always discuss alcohol use with your doctor to get personalized advice based on your health situation.

Is it safe to exercise while taking insulin glargine?

Yes, it's safe to exercise while taking insulin glargine. Exercise can help manage blood sugar levels, but be aware that it can also lower blood sugar, which is called hypoglycemia. Symptoms include dizziness and weakness. To exercise safely, monitor your blood sugar before and after activity, and carry a source of sugar, like glucose tablets. Consult your doctor for personalized exercise advice.

Is it safe to stop insulin glargine?

Stopping insulin glargine suddenly can lead to high blood sugar levels, which is called hyperglycemia, and worsen diabetes control. This can increase the risk of complications like diabetic ketoacidosis, which is a serious condition where acids build up in your blood. Always talk with your doctor before stopping insulin glargine. They can help you safely adjust your treatment plan to protect your health.

What are the most common side effects of insulin glargine?

Side effects are unwanted reactions to a medication. Common side effects of insulin glargine include low blood sugar, which is called hypoglycemia, and reactions at the injection site, such as redness or swelling. These side effects vary among individuals. If you notice new symptoms after starting insulin glargine, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication.

Who should avoid taking insulin glargine?

Insulin glargine should not be used if you are allergic to it or any of its ingredients. Severe allergic reactions, which cause rash, hives, or difficulty breathing, require immediate medical attention. Use caution if you have low blood sugar, which is called hypoglycemia, or are at risk for it. Always inform your doctor of your medical history and any other medications you are taking to ensure safe use of insulin glargine.