Furosemide

Hypertension, Chronic Kidney Failure ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

YES

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Known Teratogen

NO

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Pharmaceutical Class

Loop Diuretic

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Controlled Drug Substance

NO

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Drug Ingredient

Furosemide

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Summary

  • Furosemide is used to treat conditions like high blood pressure and edema, which is swelling due to excess fluid. This can be caused by heart, kidney or liver disease.

  • Furosemide helps the kidneys remove excess water and salt from the body through urine. This reduces fluid retention and lowers blood pressure.

  • For adults, the typical starting dose for edema is 20 to 80 mg as a single dose. For high blood pressure, it's 80 mg divided into two doses. For children, it's 2 mg per kg of body weight. Always follow your doctor's specific instructions.

  • Common side effects include frequent urination, blurred vision, headache, constipation and diarrhea. Serious effects can include hearing loss, rash, difficulty breathing, and electrolyte imbalances.

  • Furosemide should not be used by patients with an inability to urinate or those allergic to it. It can cause dehydration, electrolyte imbalances and hearing damage. Patients with liver disease, kidney disease or diabetes should use it cautiously.

Indications and Purpose

How does Furosemide work?

Furosemide works by blocking the absorption of sodium and chloride in the kidneys, leading to increased urine production. This helps remove excess fluid and salt from the body, reducing swelling and lowering blood pressure.

How does one know if Furosemide is working?

Furosemide is used to treat conditions like hypertension and edema. You can tell it's working if you notice reduced swelling, easier breathing, or lower blood pressure. These effects can be monitored through symptom improvement and regular check-ups with your healthcare provider.

Is Furosemide effective?

Furosemide is primarily used to treat conditions like hypertension and edema by helping the body remove excess fluid. Clinical trials have shown it to be effective in reducing fluid retention and lowering blood pressure. It works by increasing urine production, which helps reduce fluid buildup in the body.

What is Furosemide?

Furosemide is a medication used primarily to treat fluid retention (edema) and high blood pressure (hypertension). It works by helping the kidneys remove excess fluid and salt from the body, reducing swelling and lowering blood pressure.

What is Furosemide used for?

Furosemide is used to treat conditions like fluid retention (edema) and high blood pressure (hypertension). It helps reduce swelling and lower blood pressure by increasing urine production, which removes excess fluid and salt from the body.

Directions for Use

For how long do I take Furosemide?

Furosemide is often used for long-term management of chronic conditions like hypertension or heart failure. The duration of use depends on the condition being treated and individual response. For acute conditions, it may be used short-term. Always follow your prescriber's instructions regarding the duration of use.

How do I dispose of Furosemide?

If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.

How do I take Furosemide?

Take Furosemide as prescribed by your healthcare provider, usually once or twice daily. It can be taken with or without food. Avoid taking it late in the day to prevent nighttime urination. Follow any dietary recommendations provided by your healthcare provider.

How long does it take for Furosemide to start working?

Furosemide typically starts working within an hour of taking it, with full effects seen in about 1-2 hours. Individual factors like kidney function can affect how quickly it works. Always follow your prescriber's instructions for this medicine.

How should I store Furosemide?

Store Furosemide at room temperature, away from moisture and light. Keep it in a secure place out of reach of children. Avoid storing it in the bathroom or near a sink. There is no need for refrigeration. Always check the packaging for specific storage instructions.

What is the usual dose of Furosemide?

The usual starting dose of Furosemide for adults is 20 to 40 mg once or twice daily. The dose may be adjusted based on the individual's response and medical condition. The maximum recommended dose is 600 mg per day. For children and the elderly, dosing may differ, and adjustments are made based on specific needs. Always follow your healthcare provider's instructions for dosing.

Warnings and Precautions

Can Furosemide be taken safely while breastfeeding?

Furosemide is excreted into breast milk, but the effects on a breastfed infant are not well known. It may reduce milk supply, so caution is advised. Due to limited information, it's best to consult your healthcare provider before using Furosemide while breastfeeding. They can help weigh the benefits and risks for your specific situation.

Can Furosemide be taken safely while pregnant?

Furosemide should be used during pregnancy only if clearly needed, as there is limited data on its safety. It may affect fetal growth due to its diuretic effect. Pregnant women should consult their doctor to weigh the benefits and risks before using Furosemide.

Can I take Furosemide with other prescription drugs?

Furosemide can interact with drugs like aminoglycoside antibiotics, increasing the risk of hearing loss, and with lithium, increasing its toxicity. It may also interact with other blood pressure medications, enhancing their effects. Always inform your healthcare provider about all medications you are taking to avoid interactions.

Can I take Furosemide with vitamins or supplements?

Furosemide can cause nutrient depletion, particularly of potassium, magnesium, and calcium, necessitating supplementation. Confirmed interactions include the need for potassium supplements to prevent deficiency. Monitoring of nutrient levels is recommended. Always inform your healthcare provider about all medications and supplements you are taking.

Does Furosemide have adverse effects?

Adverse effects are harmful or unintended reactions to a medication. Furosemide can cause adverse effects such as dehydration, electrolyte imbalance, kidney dysfunction, hearing loss, and severe allergic reactions. These effects vary in frequency, with some being rare but serious, requiring immediate medical attention. Always report new symptoms to your healthcare provider and consult them before stopping any medication.

Does Furosemide have any safety warnings?

Furosemide comes with safety warnings, including the risk of dehydration and electrolyte imbalance. These can lead to symptoms like dizziness, weakness, or irregular heartbeat. It's important to monitor for these signs and maintain adequate hydration. Always follow your healthcare provider's advice and report any concerning symptoms.

Is Furosemide addictive?

Furosemide has no known potential for dependence or addiction. It is not habit-forming, and there are no behaviors or warning signs associated with addiction to this medicine. Always use Furosemide as prescribed by your healthcare provider.

Is Furosemide safe for the elderly?

Elderly patients may be more sensitive to the effects of Furosemide, particularly dehydration and electrolyte imbalances. It's important to monitor kidney function and electrolyte levels regularly. Dose adjustments may be necessary. Always follow your healthcare provider's advice and report any concerning symptoms.

Is it safe to drink alcohol while taking Furosemide?

It is generally not advisable to consume alcohol while taking Furosemide. Alcohol can enhance the blood pressure-lowering effect of Furosemide, leading to dizziness or fainting. It may also worsen dehydration, a side effect of Furosemide. If you choose to drink, limit your intake and monitor for any adverse effects. Always consult your healthcare provider for personalized advice.

Is it safe to exercise while taking Furosemide?

Most people tolerate Furosemide well, and it should not limit your ability to exercise. However, Furosemide can cause dehydration and electrolyte imbalances, which may affect physical performance. Stay hydrated and monitor for symptoms like dizziness during exercise. Consult your healthcare provider for personalized advice.

Is it safe to stop Furosemide?

Furosemide is often used for managing chronic conditions like hypertension or heart failure. Stopping it abruptly can lead to a return of symptoms or complications. There are no known withdrawal symptoms, but stopping suddenly can be risky. Always consult your doctor before stopping Furosemide to ensure it's safe to do so.

What are the most common side effects of Furosemide?

A side effect is an unwanted symptom caused by medical treatment. Common side effects of Furosemide include increased urination, dizziness, dehydration, low blood pressure, and electrolyte imbalance. These effects vary in frequency, with increased urination being very common. It's important to note that new symptoms can occur when starting any medication, which may be unrelated or temporary. Always consult a healthcare provider before stopping any medication.

Who should avoid taking Furosemide?

Furosemide should not be used in individuals with allergies to it or similar drugs, severe kidney dysfunction, or an inability to urinate. Caution is needed in those with liver disease, diabetes, or electrolyte imbalances. Always inform your healthcare provider of your medical history before starting Furosemide.