Fremanezumab
Migraine Disorders
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
No
Summary
Fremanezumab is used to prevent migraines, which are severe headaches often accompanied by nausea and sensitivity to light and sound. It is particularly effective for people with chronic migraine, which means having headaches on 15 or more days each month.
Fremanezumab works by blocking a protein called CGRP, which stands for calcitonin gene-related peptide. This protein is involved in the development of migraines. By blocking CGRP, fremanezumab helps reduce the frequency of migraine attacks.
Fremanezumab is usually given as an injection under the skin. The typical dose for adults is either 225 mg once a month or 675 mg every three months, depending on your doctor's recommendation.
Common side effects of fremanezumab include reactions at the injection site, such as pain, redness, or swelling. These effects are usually mild and temporary.
Fremanezumab may cause serious allergic reactions, which include symptoms like rash, itching, or swelling of the face, tongue, or throat. If you experience these, seek medical help immediately. Do not use fremanezumab if you are allergic to it or its ingredients.
Indications and Purpose
How does fremanezumab work?
Fremanezumab works by blocking a protein called CGRP, which is involved in migraine development. Think of it like a key that fits into a lock, preventing the lock from working. By blocking CGRP, fremanezumab helps reduce the frequency of migraine attacks. This makes it effective for people with chronic migraine.
Is fremanezumab effective?
Fremanezumab is effective in reducing the frequency of migraine attacks. Clinical studies show it significantly decreases the number of migraine days per month. This medication works by blocking a protein involved in migraine development. Many people experience fewer migraines and improved quality of life while using fremanezumab.
What is fremanezumab?
Fremanezumab is a medication used to prevent migraines. It belongs to a class of drugs called monoclonal antibodies, which are proteins designed to target specific substances in the body. Fremanezumab works by blocking a protein involved in migraine development, reducing the frequency of migraine attacks. It's typically used for long-term management of chronic migraine.
Directions for Use
For how long do I take fremanezumab?
Fremanezumab is usually a long-term medication for managing chronic migraine. You'll typically take it as prescribed by your doctor, either monthly or every three months. How long you'll need this medication depends on your response and any side effects. Always talk with your doctor before changing or stopping your treatment.
How do I dispose of fremanezumab?
Dispose of unused fremanezumab through a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, take it out of its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take fremanezumab?
Fremanezumab is usually administered as an injection under the skin. It's typically given once a month or once every three months, depending on your doctor's instructions. You can take it with or without food. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Always follow your doctor's specific instructions.
How long does it take for fremanezumab to start working?
Fremanezumab may start reducing migraine frequency within a few weeks, but full benefits might take a few months. Individual response times can vary. Regular use as prescribed by your doctor is important for achieving the best results. Keep track of your migraine frequency to monitor the medication's effectiveness.
How should I store fremanezumab?
Store fremanezumab in the refrigerator between 36°F to 46°F. Keep it in its original packaging to protect it from light. Do not freeze it. If needed, fremanezumab can be kept at room temperature for up to 7 days. Always check the expiration date and properly dispose of any unused or expired medication.
What is the usual dose of fremanezumab?
The usual dose of fremanezumab for adults is either 225 mg once a month or 675 mg every three months, depending on your doctor's recommendation. The medication is given as an injection under the skin. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can fremanezumab be taken safely while breastfeeding?
The safety of fremanezumab while breastfeeding is not well-established. It's unclear if the medication passes into breast milk. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest treatment options for managing migraines. They can help you make an informed decision.
Can fremanezumab be taken safely while pregnant?
The safety of fremanezumab during pregnancy is not well-established. Limited data is available, so it's important to weigh the benefits and risks with your doctor. If you're pregnant or planning to become pregnant, discuss the safest treatment options for managing migraines with your healthcare provider.
Can I take fremanezumab with other prescription drugs?
Fremanezumab has no major known drug interactions. However, always inform your doctor about all medications you're taking to avoid potential interactions. This helps ensure your treatment is safe and effective. Your doctor can provide guidance on any specific concerns related to your medication regimen.
Does fremanezumab have adverse effects?
Adverse effects are unwanted reactions to a medication. With fremanezumab, common adverse effects include injection site reactions like pain or redness. Serious side effects are rare but can include allergic reactions. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to fremanezumab.
Does fremanezumab have any safety warnings?
Fremanezumab has some safety warnings. It may cause allergic reactions, which can be serious. Symptoms include rash, itching, or swelling, especially of the face, tongue, or throat. If you experience these, seek medical help immediately. Always inform your doctor about any allergies or medical conditions before starting fremanezumab.
Is fremanezumab addictive?
Fremanezumab is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that fremanezumab doesn't carry this risk.
Is fremanezumab safe for the elderly?
Fremanezumab is generally safe for the elderly, but they may be more vulnerable to side effects. Older adults should be monitored for any adverse reactions. Always consult with a doctor to ensure fremanezumab is appropriate for elderly patients, considering their overall health and other medications.
Is it safe to drink alcohol while taking fremanezumab?
There's no specific interaction between fremanezumab and alcohol. However, alcohol can trigger migraines in some people. If you choose to drink, do so in moderation and monitor how it affects your migraines. Talk with your doctor about alcohol use while taking fremanezumab for personalized advice.
Is it safe to exercise while taking fremanezumab?
You can exercise while taking fremanezumab. This medication doesn't typically limit exercise capacity. However, if you experience dizziness or fatigue during physical activity, slow down or stop and rest. Most people can maintain their regular exercise routine while taking fremanezumab. Check with your doctor if you have concerns.
Is it safe to stop fremanezumab?
Fremanezumab is often used for long-term management of chronic migraine. Stopping it suddenly may lead to a return of migraine symptoms. Always talk with your doctor before stopping fremanezumab. They can help you make any medication changes safely to protect your health.
What are the most common side effects of fremanezumab?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of fremanezumab include injection site reactions like pain, redness, or swelling. These effects are usually mild and temporary. If you notice new symptoms after starting fremanezumab, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking fremanezumab?
Don't use fremanezumab if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Always inform your doctor about any allergies or medical conditions before starting fremanezumab. This helps ensure the medication is safe for you.
