Flutamide
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
Androgen Receptor Inhibitor
Controlled Drug Substance
No
flutamide
Summary
Flutamide is used to treat prostate cancer, which is a type of cancer that occurs in the prostate gland in men. It helps slow or stop the growth of cancer cells by blocking male hormones.
Flutamide works by blocking the effects of androgens, which are male hormones that can promote the growth of prostate cancer cells. This action helps slow or stop the growth of the cancer.
The usual dose of Flutamide for adults is 250 mg taken three times a day. It is taken orally, which means by mouth, and can be taken with or without food.
Common side effects of Flutamide include hot flashes, which are sudden feelings of warmth, diarrhea, and nausea, which is a feeling of sickness in the stomach.
Flutamide can cause liver damage, so regular liver function tests are necessary. It should not be used by people with severe liver disease, which is a condition where the liver is not functioning properly.
Indications and Purpose
How does Flutamide work?
Flutamide works by blocking the action of male hormones, which are called androgens, in the body. Androgens can promote the growth of prostate cancer cells. By blocking these hormones, Flutamide helps slow or stop the growth of cancer. Think of it like turning off a switch that fuels cancer growth. This action makes Flutamide effective in treating prostate cancer.
Is Flutamide effective?
Flutamide is effective in treating prostate cancer. It works by blocking the effects of male hormones, which can slow or stop the growth of cancer cells. Clinical studies show that Flutamide improves health outcomes in prostate cancer patients, reducing tumor size and slowing disease progression. It is often used in combination with other treatments for better results.
What is Flutamide?
Flutamide is a medication used to treat prostate cancer. It belongs to a class of drugs called anti-androgens, which block the effects of male hormones in the body. This helps slow or stop the growth of cancer cells. Flutamide is often used in combination with other treatments, such as surgery or radiation, to improve outcomes in prostate cancer patients.
Directions for Use
For how long do I take Flutamide?
Flutamide is usually a long-term medication for managing prostate cancer. You'll typically take it every day as part of your ongoing treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your condition to worsen. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Flutamide treatment.
How do I dispose of Flutamide?
Dispose of Flutamide by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options aren't available, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. This helps prevent harm to people and the environment.
How do I take Flutamide?
Take Flutamide as directed by your doctor, usually three times a day. You can take it with or without food. Swallow the capsules whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Avoid alcohol while taking Flutamide, as it can increase side effects.
How long does it take for Flutamide to start working?
Flutamide begins working in your body shortly after you start taking it, but noticeable effects may take several weeks. The full therapeutic effect, such as a decrease in prostate-specific antigen (PSA) levels, may take a few months. How quickly Flutamide works can depend on individual factors like your overall health and the stage of your cancer. Take it exactly as prescribed for the best results.
How should I store Flutamide?
Store Flutamide at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in the bathroom, where humidity can affect the medication. If your pills came in packaging that isn't child-resistant, transfer them to a container that children can't easily open. Always store Flutamide out of children's reach to prevent accidental swallowing. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Flutamide?
The usual starting dose of Flutamide for adults is 250 mg taken three times a day. This dose is typically maintained throughout treatment. Dose adjustments are not commonly required, but your doctor may adjust it based on your response and any side effects. There are no specific dose adjustments for children or the elderly, but close monitoring is advised. Always follow your doctor's dosing instructions for your specific health needs.
Warnings and Precautions
Can Flutamide be taken safely while breastfeeding?
Flutamide is not recommended while breastfeeding. There is limited information on whether it passes into breast milk, but it could affect a nursing infant. The medication might interfere with hormone levels, which could impact milk production. If you are breastfeeding and need treatment, talk with your doctor about safer medication options that allow you to nurse your baby safely.
Can Flutamide be taken safely while pregnant?
Flutamide is not recommended during pregnancy. It can harm an unborn baby, as it affects hormone levels. There is limited information on its use in pregnant women, but the risks are significant. If you are pregnant or planning to become pregnant, talk with your doctor about safer treatment options. They can help create a plan that protects both you and your baby.
Can I take Flutamide with other prescription drugs?
Flutamide can interact with certain medications, increasing the risk of side effects. For example, it can interact with warfarin, which is a blood thinner, increasing the risk of bleeding. It may also interact with other liver-affecting drugs, raising the risk of liver damage. Always inform your doctor about all medications you are taking to prevent interactions and ensure your treatment is safe and effective.
Does Flutamide have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Flutamide include hot flashes, diarrhea, and nausea. These occur in more than 10% of users. Serious side effects include liver damage and anemia, which require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these are related to Flutamide and suggest appropriate actions to manage them.
Does Flutamide have any safety warnings?
Yes, Flutamide has important safety warnings. It can cause liver damage, so regular liver function tests are necessary. Symptoms like nausea, vomiting, stomach pain, or jaundice, which is yellowing of the skin or eyes, require immediate medical attention. Flutamide can also cause anemia, which is a low red blood cell count, leading to fatigue. Not adhering to these warnings can result in serious health issues. Always follow your doctor's advice and report any unusual symptoms.
Is Flutamide addictive?
Flutamide is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Flutamide works by blocking the effects of male hormones in the body, which does not affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, Flutamide does not carry this risk.
Is Flutamide safe for the elderly?
Elderly patients may be more vulnerable to the side effects of Flutamide, such as liver damage and anemia, which is a low red blood cell count. Close monitoring is important to ensure safety. Regular liver function tests and blood counts are recommended. If you are elderly and taking Flutamide, talk with your doctor about any concerns and follow their advice to manage your treatment safely.
Is it safe to drink alcohol while taking Flutamide?
It's best to avoid alcohol while taking Flutamide. Alcohol can increase the risk of liver damage, which is a serious side effect of Flutamide. Drinking alcohol may also worsen other side effects like nausea or dizziness. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like stomach pain or jaundice, which is yellowing of the skin or eyes. Talk with your doctor about alcohol use while taking Flutamide.
Is it safe to exercise while taking Flutamide?
You can exercise while taking Flutamide, but be mindful of your body's response. Flutamide can cause fatigue, which might affect your exercise capacity. If you feel unusually tired or weak during workouts, slow down or stop and rest. Drink plenty of water to stay hydrated. Most people can maintain their regular exercise routine while taking Flutamide, but check with your doctor if you have concerns.
Is it safe to stop Flutamide?
Flutamide is usually used for long-term treatment of prostate cancer. Stopping it suddenly can worsen your condition. There are no specific withdrawal symptoms, but your cancer may progress if you stop treatment. Always talk with your doctor before stopping Flutamide. They can guide you on how to safely discontinue or adjust your medication to protect your health.
What are the most common side effects of Flutamide?
Side effects are unwanted reactions to a medication. Common side effects of Flutamide include hot flashes, diarrhea, and nausea, affecting more than 10% of users. These symptoms may be temporary or unrelated to the medication. If you experience new symptoms after starting Flutamide, talk with your doctor. They can help determine if the symptoms are related to the medication and advise on how to manage them.
Who should avoid taking Flutamide?
Flutamide should not be used if you have severe liver disease, as it can cause liver damage. This is an absolute contraindication. Use caution if you have a history of liver problems or are taking other medications that affect the liver. These are relative contraindications, where benefits must outweigh risks. Always consult your doctor about your medical history before starting Flutamide.
Forms / Brands
