Finerenone
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Nonsteroidal Mineralocorticoid-Receptor Antagonist
Controlled Drug Substance
No
finerenone
Summary
Finerenone is used to treat chronic kidney disease, which is a long-term condition where the kidneys don't work as well as they should, and heart failure, which is when the heart can't pump blood as well as it should.
Finerenone works by blocking mineralocorticoid receptors, which are parts of cells that can cause inflammation and scarring in the kidneys and heart. This helps improve kidney function and reduces the risk of heart problems.
The usual starting dose of Finerenone for adults is 10 mg taken once daily by mouth. Your doctor may adjust your dose based on your health needs, with a maximum recommended dose of 20 mg daily.
Common side effects of Finerenone include increased potassium levels, which can be dangerous if too high, and low blood pressure, which can make you feel dizzy or faint.
Do not take Finerenone if you have high potassium levels or severe kidney problems. Regular blood tests are needed to monitor potassium levels. Always follow your doctor's advice and attend all scheduled check-ups.
Indications and Purpose
How does Finerenone work?
Finerenone works by blocking mineralocorticoid receptors in the body, which reduces inflammation and fibrosis in the kidneys and heart. This helps improve kidney function and reduces the risk of heart-related complications. Think of it like turning off a switch that causes damage, allowing your organs to heal.
Is Finerenone effective?
Finerenone is effective in treating chronic kidney disease and heart failure. It works by blocking certain receptors in the body, which helps reduce inflammation and fibrosis in the kidneys and heart. Clinical studies show Finerenone improves kidney function and reduces the risk of heart-related complications.
What is Finerenone?
Finerenone is a medication used to treat chronic kidney disease and heart failure. It belongs to a class of drugs called mineralocorticoid receptor antagonists, which work by blocking certain receptors in the body. This helps reduce inflammation and fibrosis in the kidneys and heart, improving their function.
Directions for Use
For how long do I take Finerenone?
Finerenone is usually a long-term medication for managing chronic conditions like heart failure and chronic kidney disease. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Always talk with your doctor before changing or stopping your Finerenone treatment.
How do I dispose of Finerenone?
Bring unused Finerenone to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash.
How do I take Finerenone?
Take Finerenone as prescribed by your doctor, usually once daily. You can take it with or without food. Do not crush or chew the tablet. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Avoid taking two doses at once. Follow your doctor's advice on diet and fluid intake while on this medication.
How long does it take for Finerenone to start working?
Finerenone begins working in your body shortly after you take it, but you may not notice all the benefits right away. For chronic kidney disease and heart failure, the full benefits may take weeks to months to appear. How quickly it works can depend on your overall health and condition.
How should I store Finerenone?
Store Finerenone at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of reach of children. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Finerenone?
The usual starting dose of Finerenone for adults is 10 mg once daily. Your doctor may adjust your dose based on your response and health needs. The maximum recommended dose is 20 mg daily. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can Finerenone be taken safely while breastfeeding?
Finerenone is not recommended while breastfeeding due to limited information on its safety. We don't know if it passes into human breast milk or its effects on a breastfed baby. If you're breastfeeding, talk with your doctor about safer medication options.
Can Finerenone be taken safely while pregnant?
Finerenone isn't recommended during pregnancy due to limited safety data. Animal studies suggest potential risks to the developing baby. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition during this time.
Can I take Finerenone with other prescription drugs?
Finerenone can interact with medications that increase potassium levels, such as certain diuretics and ACE inhibitors. These interactions can increase the risk of high potassium, which can be dangerous. Always inform your doctor about all medications you're taking to avoid potential interactions.
Does Finerenone have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Finerenone include increased potassium levels and low blood pressure. Serious side effects can include kidney problems. If you notice any new or worsening symptoms, contact your doctor immediately.
Does Finerenone have any safety warnings?
Yes, Finerenone has important safety warnings. It can increase potassium levels in your blood, which can be dangerous. Regular blood tests are needed to monitor this. Not adhering to these warnings can lead to serious heart problems. Always follow your doctor's advice and attend all scheduled blood tests.
Is Finerenone addictive?
Finerenone is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. This medication works by affecting your kidneys to help manage your condition, and it doesn't affect brain chemistry in ways that could lead to addiction.
Is Finerenone safe for the elderly?
Elderly patients are more vulnerable to medication risks due to age-related changes in kidney function and other health conditions. Finerenone is generally safe for the elderly, but they may experience more frequent side effects like low blood pressure. Regular monitoring by a doctor is important.
Is it safe to drink alcohol while taking Finerenone?
It's best to avoid alcohol while taking Finerenone. Alcohol can increase the risk of dehydration and low blood pressure, which may worsen side effects. If you choose to drink, limit your intake and watch for warning signs like dizziness or fainting. Talk with your doctor about alcohol use while on this medication.
Is it safe to exercise while taking Finerenone?
You can exercise while taking Finerenone, but be cautious. This medication can cause low blood pressure, which might make you feel dizzy during exercise. Stay hydrated and avoid strenuous activities if you feel unwell. Talk with your doctor if you have concerns about exercising while on this medication.
Is it safe to stop Finerenone?
Stopping Finerenone suddenly can cause your condition to worsen. It's used for long-term management of conditions like heart failure and chronic kidney disease. Always talk with your doctor before stopping Finerenone. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.
What are the most common side effects of Finerenone?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Finerenone include increased potassium levels and low blood pressure. If you notice new symptoms after starting Finerenone, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Finerenone?
Don't take Finerenone if you have high potassium levels or severe kidney problems. These are absolute contraindications due to severe risks. Use caution if you have liver problems or are taking other medications that increase potassium levels. Always consult your doctor about these concerns.
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