Etravirine
HIV Infections
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor
Controlled Drug Substance
No
Summary
Etravirine is used to treat HIV-1 infection, which is a type of virus that attacks the immune system. It helps lower the amount of virus in the blood, improving immune function and reducing the risk of complications.
Etravirine works by blocking the reverse transcriptase enzyme, which the HIV virus uses to multiply. This action helps prevent the virus from making copies of itself, lowering the viral load in the body and improving immune function.
The usual starting dose of Etravirine for adults is 200 mg taken twice daily after meals. It is important to follow your doctor's specific dosing instructions and not to stop the medication without medical advice.
Common side effects of Etravirine include rash, nausea, and diarrhea. These effects vary from person to person, and if you notice any new symptoms, it's important to talk with your doctor.
Etravirine can cause severe skin reactions and should not be taken if you are allergic to it. It can interact with other medications, so always inform your doctor about all drugs you are taking to avoid potential interactions.
Indications and Purpose
How does Etravirine work?
Etravirine works by blocking the reverse transcriptase enzyme, which the HIV virus uses to multiply. Think of it like putting a lock on a door to stop unwanted guests. By blocking this enzyme, Etravirine prevents the virus from making copies of itself, helping to lower the viral load in your body. This improves your immune function and helps manage HIV.
Is Etravirine effective?
Etravirine is effective in treating HIV-1 infection. It works by blocking the virus's ability to multiply, helping to lower the viral load in your body. Clinical studies show that Etravirine improves health outcomes in people with HIV, reducing the risk of complications and improving immune function. Always take Etravirine as prescribed by your doctor for the best results.
What is Etravirine?
Etravirine is a medication used to treat HIV-1 infection. It belongs to a class of drugs called non-nucleoside reverse transcriptase inhibitors, which work by blocking the virus's ability to multiply. This helps lower the viral load in your body and improves immune function. Etravirine is used in combination with other antiretroviral medications to effectively manage HIV.
Directions for Use
For how long do I take Etravirine?
Etravirine is usually a long-term medication for managing HIV-1 infection. You'll typically take it every day as part of your ongoing treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your condition to worsen. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Etravirine treatment.
How do I dispose of Etravirine?
Dispose of unused Etravirine by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away. This helps prevent harm to people and the environment.
How do I take Etravirine?
Take Etravirine as prescribed by your doctor, usually twice daily after meals. Swallow the tablets whole with water. Do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Etravirine to start working?
Etravirine begins working in your body shortly after you take it, but you may not notice all the benefits right away. It helps lower the viral load, which is the amount of virus in your blood, over time. Regular blood tests will monitor your progress. How quickly Etravirine works can depend on your overall health and adherence to the treatment plan. Always take it as prescribed for the best results.
How should I store Etravirine?
Store Etravirine at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Etravirine out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Etravirine?
The usual starting dose of Etravirine for adults is 200 mg taken twice daily after meals. Your doctor may adjust your dose based on your response to the medication. It's important to follow your doctor's specific dosing instructions. Etravirine is not typically used in children, and elderly patients may require careful monitoring. Always consult your doctor for personalized dosing advice.
Warnings and Precautions
Can Etravirine be taken safely while breastfeeding?
Etravirine is not recommended while breastfeeding. It's unclear if this medication passes into human breast milk. HIV can be transmitted to the baby through breast milk, so breastfeeding is generally not recommended for mothers with HIV. Talk with your doctor about safer feeding options for your baby while managing your HIV treatment.
Can Etravirine be taken safely while pregnant?
Etravirine's safety during pregnancy is not well-established. Limited data is available, so it's important to weigh the benefits and risks with your doctor. Uncontrolled HIV during pregnancy can cause serious problems for both mother and baby. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your HIV treatment.
Can I take Etravirine with other prescription drugs?
Etravirine can interact with several medications, including certain antiretrovirals, anticonvulsants, and antibiotics. These interactions can increase the risk of side effects or reduce the effectiveness of Etravirine. Always inform your doctor about all medications you are taking to avoid potential interactions. Your doctor can adjust your treatment plan to ensure it's safe and effective.
Does Etravirine have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Etravirine include rash and nausea. Serious side effects can include severe skin reactions and liver problems. If you notice any new or worsening symptoms, contact your doctor immediately. It's important to report adverse effects to ensure your treatment remains safe and effective.
Does Etravirine have any safety warnings?
Etravirine has important safety warnings. It can cause severe skin reactions, which may require immediate medical attention. If you experience a rash, fever, or blisters, contact your doctor right away. Etravirine can also interact with other medications, so inform your doctor about all drugs you are taking. Not adhering to these warnings can lead to serious health issues.
Is Etravirine addictive?
Etravirine is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. Etravirine works by affecting the virus that causes HIV, not brain chemistry, so it doesn't lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. Always follow your doctor's instructions for safe use.
Is Etravirine safe for the elderly?
Elderly patients may be more vulnerable to side effects of Etravirine due to age-related changes in liver and kidney function. It's important for older adults to be closely monitored by their doctor while taking this medication. Regular check-ups help ensure the treatment is safe and effective, and any side effects are managed promptly.
Is it safe to drink alcohol while taking Etravirine?
It's best to avoid alcohol while taking Etravirine. Alcohol can affect your liver, which is important for processing medications. Drinking alcohol may increase the risk of liver problems and worsen side effects. If you choose to drink, do so in moderation and talk with your doctor about your alcohol use to get personalized advice.
Is it safe to exercise while taking Etravirine?
You can exercise while taking Etravirine, but listen to your body. If you feel dizzy or fatigued, take a break. Regular exercise is beneficial for overall health, but avoid strenuous activities if you experience side effects. Stay hydrated and talk with your doctor if you have concerns about your exercise routine while on Etravirine.
Is it safe to stop Etravirine?
Stopping Etravirine suddenly can affect your HIV treatment. It may lead to an increase in viral load, which is the amount of virus in your blood, and worsen your condition. Always talk with your doctor before stopping Etravirine. They might suggest a different medication or a gradual reduction in dose to keep your condition under control.
What are the most common side effects of Etravirine?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Etravirine include rash, nausea, and diarrhea. These effects vary from person to person. If you notice new symptoms after starting Etravirine, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Etravirine?
Don't take Etravirine if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Etravirine should be used with caution in people with severe liver problems. Always inform your doctor about your medical history and any other medications you are taking to avoid potential interactions and ensure safe use.
