Ethinyl-estradiol + Gestodene
.svg)
Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
No
Summary
Ethinyl estradiol and gestodene are primarily used as contraceptives to prevent pregnancy. They also help regulate menstrual cycles, reduce menstrual pain, and manage symptoms of premenstrual syndrome, which is a group of symptoms occurring between ovulation and a period. These benefits arise from their ability to prevent ovulation and stabilize hormone levels in the body.
Ethinyl estradiol, a synthetic estrogen, prevents ovulation by stopping the release of eggs from the ovaries and stabilizes the uterine lining, which is the inner layer of the uterus. Gestodene, a synthetic progestin, thickens cervical mucus, making it difficult for sperm to enter the uterus, and also prevents ovulation. Together, they provide effective contraception.
The usual adult dose of ethinyl estradiol and gestodene is one tablet taken once a day. Ethinyl estradiol is typically present in a low dose, around 20 to 35 micrograms, while gestodene is included in a dose of about 75 to 150 micrograms. These doses are combined in a single tablet to provide effective contraception. It's important to take the tablet at the same time each day.
Common side effects of ethinyl estradiol and gestodene include nausea, headaches, and breast tenderness. Ethinyl estradiol may cause changes in mood and weight gain, while gestodene can lead to changes in menstrual flow. Significant adverse effects, though rare, include an increased risk of blood clots, which can lead to serious conditions like deep vein thrombosis or pulmonary embolism.
Ethinyl estradiol and gestodene should not be used by women who smoke and are over 35, due to an increased risk of cardiovascular issues like blood clots. They are contraindicated in women with a history of blood clots, certain cancers, or liver disease. It's crucial to have a thorough medical evaluation before starting these medications and to monitor for symptoms like severe headaches or leg pain.
Indications and Purpose
How does combination of Ethinyl Estradiol and Gestodene work?
Ethinyl Estradiol is a synthetic form of estrogen, which is a hormone that regulates the menstrual cycle and reproductive system. It works by preventing the release of an egg from the ovary, which is known as ovulation. It also thickens the mucus in the cervix, which is the lower part of the uterus, making it harder for sperm to enter the uterus. Gestodene is a synthetic form of progesterone, which is another hormone involved in the menstrual cycle. It also prevents ovulation and alters the uterine lining, which is the inner layer of the uterus, to prevent a fertilized egg from implanting. Both Ethinyl Estradiol and Gestodene work together in birth control pills to prevent pregnancy. They share the common goal of stopping ovulation and making it difficult for sperm to reach any egg that might be released. Together, they provide effective contraception.
How effective is combination of Ethinyl Estradiol and Gestodene?
Ethinyl Estradiol and Gestodene are used together in birth control pills to prevent pregnancy. Ethinyl Estradiol, which is a synthetic form of estrogen, helps regulate the menstrual cycle and prevents ovulation, which is the release of an egg from the ovary. Gestodene, which is a synthetic form of progesterone, thickens the cervical mucus to block sperm and alters the uterine lining to prevent a fertilized egg from implanting. Both substances work together to provide effective contraception by preventing ovulation and creating an environment that is not conducive to pregnancy. They are commonly used in combination because they complement each other’s actions, providing a reliable method of birth control. The combination is well-studied and has been shown to be effective in preventing pregnancy when taken as directed. Common attributes include their role in regulating hormones and preventing ovulation, while their unique attributes lie in their specific hormonal actions.
Directions for Use
What is the usual dose of combination of Ethinyl Estradiol and Gestodene?
The usual adult daily dose for Ethinyl Estradiol, which is a synthetic form of estrogen used in birth control pills, is typically 20 to 35 micrograms. For Gestodene, which is a synthetic progestogen also used in birth control, the usual dose is around 75 micrograms. Ethinyl Estradiol works by preventing ovulation, which is the release of an egg from the ovary, and it also thickens the cervical mucus to block sperm. Gestodene also prevents ovulation and alters the uterine lining to prevent a fertilized egg from implanting. Both medicines are used together in combination birth control pills to effectively prevent pregnancy. They share the common attribute of regulating menstrual cycles and reducing the risk of ovarian cysts. However, Ethinyl Estradiol is more focused on estrogenic effects, while Gestodene provides progestogenic effects.
How does one take combination of Ethinyl Estradiol and Gestodene?
Ethinyl Estradiol and Gestodene are often combined in birth control pills. These medicines can be taken with or without food, so you can choose what works best for you. There are no specific food restrictions, but it's always a good idea to maintain a balanced diet. Ethinyl Estradiol, which is a synthetic form of estrogen, helps prevent ovulation, which means it stops the release of an egg from the ovary. Gestodene, which is a synthetic form of progesterone, also helps prevent ovulation and makes it harder for sperm to reach the uterus. Both medicines work together to prevent pregnancy. It's important to take the pill at the same time every day for it to be most effective. If you have any concerns or experience side effects, it's best to talk to your healthcare provider.
For how long is combination of Ethinyl Estradiol and Gestodene taken?
Ethinyl Estradiol and Gestodene are often used together in birth control pills. The typical duration of use for these medicines is usually on a monthly cycle, where they are taken for 21 days followed by a 7-day break. Ethinyl Estradiol, which is a synthetic form of estrogen, helps regulate the menstrual cycle and prevent ovulation, which means the release of an egg from the ovary. Gestodene, which is a synthetic form of progesterone, also prevents ovulation and thickens the cervical mucus, making it harder for sperm to enter the uterus. Both substances work together to prevent pregnancy. They share the common attribute of being used in hormonal contraceptives, but Ethinyl Estradiol is primarily responsible for controlling the menstrual cycle, while Gestodene focuses on preventing ovulation and altering cervical mucus.
How long does it take for combination of Ethinyl Estradiol and Gestodene to work?
The time it takes for a combination medicine to start working depends on the individual medicines involved. For example, if the combination includes ibuprofen, which is a pain reliever and anti-inflammatory, it typically starts working within 20 to 30 minutes. If the combination includes paracetamol, which is another pain reliever, it usually begins to work within 30 to 60 minutes. Both medicines are used to relieve pain and reduce fever, which means they share these common attributes. However, ibuprofen also reduces inflammation, which is swelling and redness, while paracetamol does not. When combined, these medicines can provide a broader range of relief, addressing both pain and inflammation more effectively. Always follow the dosage instructions provided by a healthcare professional to ensure safe and effective use.
Warnings and Precautions
Are there harms and risks from taking combination of Ethinyl Estradiol and Gestodene?
Ethinyl Estradiol, which is a synthetic form of estrogen, and Gestodene, which is a synthetic form of progesterone, are often used together in birth control pills. Common side effects of these medications include nausea, headaches, and breast tenderness. Some people may also experience mood changes or weight gain. Significant adverse effects can include an increased risk of blood clots, which are clumps of blood that can block blood vessels, and high blood pressure, which is when the force of blood against artery walls is too high. Ethinyl Estradiol can cause changes in menstrual flow, while Gestodene may lead to acne or oily skin. Both medications share the risk of causing liver problems, which can affect how the liver functions. It's important to discuss any concerns with a healthcare provider.
Can I take combination of Ethinyl Estradiol and Gestodene with other prescription drugs?
Ethinyl Estradiol and Gestodene are often used together in birth control pills. Ethinyl Estradiol, which is a synthetic form of estrogen, and Gestodene, which is a synthetic form of progesterone, work together to prevent ovulation, which is the release of an egg from the ovary. Both substances can interact with other medications. For example, certain antibiotics and anticonvulsants, which are drugs used to treat seizures, can reduce the effectiveness of Ethinyl Estradiol and Gestodene, increasing the risk of unintended pregnancy. Unique to Ethinyl Estradiol, it can increase the risk of blood clots, especially when combined with other medications that affect blood clotting. Gestodene, on the other hand, is known for its high potency, meaning it is effective in small doses. Both drugs share the common attribute of being affected by liver enzyme inducers, which are substances that increase the activity of liver enzymes, potentially reducing their effectiveness.
Can I take combination of Ethinyl Estradiol and Gestodene if I am pregnant?
Ethinyl Estradiol, which is a synthetic form of estrogen, and Gestodene, which is a synthetic form of progesterone, are both used in combination as oral contraceptives. During pregnancy, these substances are not recommended because they are designed to prevent pregnancy, not support it. Ethinyl Estradiol can affect hormone levels, which are crucial for a healthy pregnancy. Gestodene, on the other hand, can alter the uterine lining, which is important for embryo implantation. Both substances share the common attribute of being hormonal contraceptives, meaning they work by altering the body's natural hormone levels to prevent ovulation. It is important to stop taking these medications if pregnancy is suspected or confirmed, as they are not intended for use during pregnancy and could potentially harm the developing fetus.
Can I take combination of Ethinyl Estradiol and Gestodene while breastfeeding?
Ethinyl Estradiol, which is a synthetic form of estrogen, and Gestodene, which is a synthetic form of progesterone, are often used together in birth control pills. During breastfeeding, small amounts of these hormones can pass into breast milk. Ethinyl Estradiol may reduce milk production, especially in the early weeks after childbirth. Gestodene is considered to have a lower impact on milk production compared to Ethinyl Estradiol. Both substances are generally considered safe for the breastfeeding infant, but it is always best to consult a healthcare provider. Common attributes include their role in preventing pregnancy and their potential to affect milk supply. Unique to Ethinyl Estradiol is its stronger influence on reducing milk production, while Gestodene is noted for its lower impact on lactation.
Who should avoid taking combination of Ethinyl Estradiol and Gestodene?
Ethinyl Estradiol and Gestodene are used together in birth control pills. Ethinyl Estradiol, which is a synthetic form of estrogen, can increase the risk of blood clots, especially in smokers and women over 35. Gestodene, which is a synthetic form of progesterone, can also contribute to this risk. Both substances should not be used by women with a history of blood clots, certain cancers, or liver disease. They can also raise blood pressure, so monitoring is important. Common side effects include nausea, headaches, and mood changes. It's crucial to inform your doctor of any other medications you're taking, as these can interact with Ethinyl Estradiol and Gestodene, reducing their effectiveness or increasing side effects. Always consult a healthcare provider to ensure these medications are safe for you.
