Eszopiclone
Sleep Initiation and Maintenance Disorders
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
YES
Eszopiclone
Summary
Eszopiclone is used to treat insomnia, specifically difficulties with falling asleep and staying asleep. It helps improve sleep quality and duration in individuals experiencing sleep disturbances.
Eszopiclone works by interacting with GABA-receptor complexes in the brain, enhancing the effects of the neurotransmitter GABA. This action slows down brain activity, promoting relaxation and sleep.
The recommended starting dose of Eszopiclone for adults is 1 mg, which can be increased to 2 mg or 3 mg if needed. The total dose should not exceed 3 mg per day. It should be taken orally immediately before bedtime.
Common side effects of Eszopiclone include headache, drowsiness, dizziness, and an unpleasant taste. Serious adverse effects can include complex sleep behaviors and severe allergic reactions.
Eszopiclone may cause complex sleep behaviors such as sleep-driving and sleepwalking, which can be dangerous. It's not recommended for those with a history of these behaviors or hypersensitivity to the drug. Alcohol and other CNS depressants should be avoided while taking Eszopiclone.
Indications and Purpose
How does Eszopiclone work?
Eszopiclone works by affecting chemicals in the brain that may be unbalanced in people with sleep problems. It belongs to a class of drugs called sedative-hypnotics, which help slow down brain activity to promote sleep. Think of it like dimming the lights in a room to create a calming environment. This effect helps you fall asleep faster and stay asleep longer, improving sleep quality.
Is Eszopiclone effective?
Yes, Eszopiclone is effective for treating insomnia, which is difficulty falling or staying asleep. It works by helping you fall asleep faster and stay asleep longer. Clinical studies show that Eszopiclone improves sleep quality and duration in people with insomnia. It's important to use it as part of a comprehensive treatment plan, including good sleep habits, for the best results.
What is Eszopiclone?
Eszopiclone is a medication used to treat insomnia, which is difficulty falling or staying asleep. It belongs to a class of drugs called sedative-hypnotics, which work by slowing brain activity to help you sleep. Eszopiclone is usually taken right before bedtime to improve sleep quality and duration. It's important to use it as part of a comprehensive treatment plan, including good sleep habits, for the best results.
Directions for Use
For how long do I take Eszopiclone?
Eszopiclone is usually prescribed for short-term use to treat insomnia, which is difficulty falling or staying asleep. The typical duration is a few weeks, but your doctor will determine the best length for your treatment based on your needs. Long-term use is generally not recommended due to the risk of dependence. Always follow your doctor's instructions and discuss any concerns about the duration of your treatment.
How do I dispose of Eszopiclone?
Dispose of Eszopiclone by taking it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If no take-back program is available, mix the medication with something undesirable, like used coffee grounds, seal it in a plastic bag, and throw it in the trash.
How do I take Eszopiclone?
Take Eszopiclone exactly as prescribed by your doctor. It's usually taken once daily, right before bedtime, to help with sleep. Swallow the tablet whole; do not crush or chew it. You can take it with or without food, but avoid high-fat meals as they can delay its effect. If you miss a dose, skip it and take your next dose at the regular time. Do not take two doses at once. Avoid alcohol while taking Eszopiclone, as it can increase drowsiness and dizziness.
How long does it take for Eszopiclone to start working?
Eszopiclone starts working quickly, usually within 30 minutes after taking it. You'll likely feel its effects as you begin to feel drowsy and ready for sleep. The full therapeutic effect, which is improved sleep quality and duration, is typically noticeable after the first dose. Individual factors like age, liver function, and overall health can affect how quickly Eszopiclone works. Take it exactly as prescribed for the best results.
How should I store Eszopiclone?
Store Eszopiclone at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Eszopiclone out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Eszopiclone?
The usual starting dose of Eszopiclone for adults is 1 mg taken once daily, right before bedtime. Your doctor may adjust the dose based on your response and needs, with a maximum recommended dose of 3 mg per day. For elderly patients or those with liver problems, a lower starting dose of 1 mg is recommended. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can Eszopiclone be taken safely while breastfeeding?
Eszopiclone is not recommended while breastfeeding. Limited information is available on whether it passes into breast milk. Potential risks to the breastfed infant are unknown. If you're taking Eszopiclone and want to breastfeed, talk with your doctor about safer medication options. Your doctor can help you choose a treatment that allows you to nurse your baby safely.
Can Eszopiclone be taken safely while pregnant?
Eszopiclone is not recommended during pregnancy due to limited safety information. Animal studies suggest potential risks, but human data is lacking. Uncontrolled insomnia during pregnancy can affect both mother and baby. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage sleep issues. Your doctor can help create a pregnancy-specific treatment plan.
Can I take Eszopiclone with other prescription drugs?
Eszopiclone can interact with other medications that cause drowsiness, such as opioids, benzodiazepines, and certain antidepressants. These interactions can increase the risk of excessive sedation and respiratory depression, which is slowed breathing. Always inform your doctor about all medications you are taking to avoid potential interactions. Your doctor can adjust your treatment plan to ensure safety and effectiveness.
Does Eszopiclone have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Eszopiclone include drowsiness, dizziness, and headache. These occur in a small percentage of users. Serious side effects, like complex sleep behaviors or allergic reactions, are rare but require immediate medical attention. If you notice any new or worsening symptoms while taking Eszopiclone, contact your doctor to discuss your treatment.
Does Eszopiclone have any safety warnings?
Yes, Eszopiclone has important safety warnings. It can cause drowsiness, which may affect your ability to drive or operate machinery. Avoid alcohol, as it can increase drowsiness and dizziness. Eszopiclone may cause complex sleep behaviors, like sleepwalking or sleep-driving, which can be dangerous. If you experience these, stop taking the medication and contact your doctor. Not adhering to these warnings can lead to serious accidents or injuries.
Is Eszopiclone addictive?
Yes, Eszopiclone can be habit-forming, meaning it has the potential for addiction. This occurs because the medication affects brain chemistry, leading to physical or psychological dependence. Warning signs include needing higher doses to achieve the same effect or experiencing withdrawal symptoms when not taking it. To prevent dependence, use Eszopiclone only as prescribed by your doctor and avoid increasing the dose on your own.
Is Eszopiclone safe for the elderly?
Elderly individuals are more vulnerable to the side effects of Eszopiclone, such as dizziness and drowsiness, which can increase the risk of falls. It's important to use the lowest effective dose and monitor for any adverse effects. Regular check-ups with a doctor can help ensure the medication is safe and effective for elderly users.
Is it safe to drink alcohol while taking Eszopiclone?
It's best to avoid alcohol while taking Eszopiclone. Alcohol can increase the sedative effects of the medication, leading to excessive drowsiness, dizziness, or impaired coordination. This combination can be dangerous and increase the risk of accidents. If you choose to drink occasionally, limit your alcohol intake and be aware of any warning signs like extreme drowsiness. Talk with your doctor about alcohol use while taking Eszopiclone.
Is it safe to exercise while taking Eszopiclone?
You can exercise while taking Eszopiclone, but be cautious. The medication can cause drowsiness or dizziness, which might affect your balance and coordination during physical activity. To exercise safely, avoid strenuous activities or high-impact sports until you know how Eszopiclone affects you. If you feel dizzy or unusually tired, stop exercising and rest. Consult your doctor if you have concerns about exercising while on this medication.
Is it safe to stop Eszopiclone?
Stopping Eszopiclone suddenly can cause withdrawal symptoms like anxiety, unusual dreams, or difficulty sleeping. It's usually used short-term for sleep problems. If you need to stop, your doctor may suggest gradually reducing the dose to minimize withdrawal effects. Always talk with your doctor before stopping Eszopiclone to ensure a safe and effective discontinuation plan.
What are the most common side effects of Eszopiclone?
Side effects are unwanted reactions to a medication. Common side effects of Eszopiclone include drowsiness, dizziness, and a metallic taste in the mouth. These occur in a small percentage of people taking the medication. If you experience new symptoms after starting Eszopiclone, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Eszopiclone?
Do not use Eszopiclone if you have a known allergy to it or its ingredients. Serious allergic reactions, which cause rash, hives, or difficulty breathing, require immediate medical help. Use caution if you have a history of substance abuse, as Eszopiclone can be habit-forming. Always consult your doctor about any health concerns before starting Eszopiclone.
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