Estradiol

Prostatic Neoplasms, Premature Menopause ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

YES

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Known Teratogen

NO

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Pharmaceutical Class

Estrogen

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Controlled Drug Substance

NO

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Drug Ingredient

Estradiol

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Summary

  • Estradiol is used to treat symptoms related to menopause such as hot flashes and vaginal dryness. It's also used for hormone replacement therapy after menopause, for low estrogen levels, and to prevent osteoporosis. Additionally, it's used in birth control pills, gender-affirming therapy for transgender women, and certain gynecological disorders like endometriosis.

  • Estradiol is a potent form of estrogen, a hormone found in high levels in women of childbearing age. It works by replacing the estrogen that the body is no longer making, helping to reduce symptoms of menopause. It also helps to keep bones strong and prevent fractures.

  • The usual daily dose of Estradiol for adults is 0.5 to 2 mg taken orally for menopause symptoms and 0.5 mg for osteoporosis prevention. It's available in different forms like pills and patches. Always take Estradiol as directed by your doctor.

  • Common side effects include upset stomach, nausea, vomiting, headaches, dizziness, mood swings, weight changes, and changes in sex drive. Serious side effects can include stroke, blood clots, heart attack, cancer, and liver problems. If you experience any of these, it's important to consult your doctor immediately.

  • Estradiol should not be used if you're pregnant or breastfeeding. It may cause side effects similar to birth control pills. Older women taking certain estrogen medications may have an increased risk of stroke, heart attack, breast cancer, and dementia. Always inform your doctor of any other medications or supplements you're taking to avoid potential interactions.

Indications and Purpose

Directions for Use

Warnings and Precautions