Disopyramide
Atrial Premature Complexes, Atrial Fibrillation ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Antiarrhythmic
Controlled Drug Substance
NO
Disopyramide
Learn more about this medicine -
Click HereSummary
Disopyramide is used to treat certain types of irregular heartbeats, particularly life-threatening ventricular arrhythmias. It helps control the condition but does not cure it.
Disopyramide works by decreasing the rate of diastolic depolarization in cells with augmented automaticity, reducing the upstroke velocity and increasing the action potential duration of normal cardiac cells. This makes the heart more resistant to abnormal activity.
For adults, the usual daily dose of Disopyramide is 400 to 800 mg, divided into doses throughout the day. Typically, adults take 150 mg every 6 hours. For children, the dosage is based on body weight and age with close monitoring of plasma levels and therapeutic response.
Common side effects include dry mouth, urinary hesitancy, constipation, and fatigue. Serious side effects include chest pain, irregular heartbeat, and shortness of breath. Unusual weight gain and impotence are also reported.
Disopyramide may increase the risk of death in patients with heart disease. It is contraindicated in patients with cardiogenic shock, certain heart blocks, and known hypersensitivity. It can cause or worsen heart failure and hypotension. Pregnant and nursing women, and elderly patients should use it with caution.
Indications and Purpose
What is Disopyramide used for?
Disopyramide is indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, which are considered life-threatening. It is not recommended for less severe arrhythmias or asymptomatic conditions.
How does Disopyramide work?
Disopyramide works by decreasing the rate of diastolic depolarization in cells with augmented automaticity, reducing the upstroke velocity, and increasing the action potential duration of normal cardiac cells. This helps make the heart more resistant to abnormal activity.
Is Disopyramide effective?
Most people tolerate Glimepiride well, and difficulty thinking or concentrating is not commonly reported. If you experience cognitive issues, consult a healthcare provider.
How does one know if Disopyramide is working?
The benefit of Disopyramide is evaluated through regular medical appointments and laboratory tests to monitor heart function and response to the medication. Keep all appointments with your doctor for effective management.
Directions for Use
What is the usual dose of Disopyramide?
A side effect is an unwanted or unexpected symptom caused by a medication. Common side effects of Clopidogrel include bleeding, bruising, diarrhea, and rash. The frequency of these side effects can vary, but they are generally not experienced by everyone. It's important to note that when starting a new medication, some symptoms may be coincidental, unrelated, or temporary. Always consult a healthcare provider before stopping any medication.
How do I take Disopyramide?
Disopyramide should be taken exactly as prescribed by your doctor, usually every 6 or 8 hours for regular capsules, or every 12 hours for extended-release capsules. There are no specific food restrictions, but always follow your doctor's advice regarding diet and medication.
How long does it take for Disopyramide to start working?
Therapeutic effects of Disopyramide are usually attained 30 minutes to 3 hours after administration of a loading dose. However, the exact time may vary based on individual response and dosage.
How should I store Disopyramide?
Clopidogrel is used to prevent blood clots in people with heart disease, stroke, or peripheral artery disease. It helps reduce the risk of heart attack and stroke by preventing platelets from sticking together. It may be used alone or with other treatments.
Warnings and Precautions
Who should avoid taking Disopyramide?
Most people tolerate Glimepiride well, and sexual side effects are not commonly reported. If you experience changes in sexual function, consult a healthcare provider.
Can I take Disopyramide with other prescription drugs?
Disopyramide can interact with other antiarrhythmic drugs, increasing the risk of serious side effects. It may also interact with CYP3A4 inhibitors like erythromycin, leading to potentially fatal interactions. Always inform your doctor of all medications you are taking.
Can Disopyramide be taken safely while pregnant?
Disopyramide should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. There are no adequate and well-controlled studies in pregnant women, so consult your doctor for personalized advice.
Can Disopyramide be taken safely while breastfeeding?
Disopyramide is found in breast milk, and due to the potential for serious adverse reactions in nursing infants, a decision should be made to either discontinue nursing or the drug, considering its importance to the mother.
Is Disopyramide safe for the elderly?
Most people tolerate Glimepiride well, and it should not limit your ability to exercise. However, monitor for symptoms of low blood sugar during physical activity and take precautions as needed.
Is it safe to exercise while taking Disopyramide?
Dapoxetine may cause dizziness or drowsiness, which could impair your ability to drive. Avoid driving until you know how the medication affects you. If you experience any symptoms that could impair driving, consult your healthcare provider.
Is it safe to drink alcohol while taking Disopyramide?
Most people tolerate Bisoprolol well, and it should not limit your ability to drink caffeinated beverages such as coffee or tea. There are no known interactions between Bisoprolol and caffeine that would interfere with the medication's effectiveness or cause harm.
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