Daridorexant
Sleep Initiation and Maintenance Disorders
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Orexin Receptor Antagonist
Controlled Drug Substance
No
daridorexant
Summary
Daridorexant is used to treat insomnia, which is difficulty falling or staying asleep. It helps improve sleep quality and duration, allowing individuals to fall asleep faster and stay asleep longer.
Daridorexant works by blocking orexin receptors, which are involved in wakefulness. This action reduces the brain signals that keep you awake, helping you fall asleep faster and stay asleep longer.
The usual starting dose of Daridorexant for adults is 25 mg once daily in the evening. The maximum recommended dose is 50 mg per day. It should be taken without food to help it work best.
Common side effects of Daridorexant include drowsiness and dizziness, which are feelings of sleepiness and lightheadedness. These effects can vary from person to person.
Avoid alcohol while taking Daridorexant, as it can increase drowsiness. Do not drive until you know how the medication affects you. Consult your doctor if you have liver problems or are pregnant.
Indications and Purpose
How does Daridorexant work?
Daridorexant works by blocking orexin receptors in the brain, which are involved in wakefulness. Think of it like turning down the volume on a loudspeaker. By reducing the signals that keep you awake, Daridorexant helps you fall asleep faster and stay asleep longer. This makes it effective for treating insomnia, which is difficulty falling or staying asleep.
Is Daridorexant effective?
Daridorexant is effective for treating insomnia, which is difficulty falling or staying asleep. Clinical studies show it helps improve sleep quality and duration. People using Daridorexant often report better sleep and feeling more rested. Always follow your doctor's instructions to achieve the best results.
What is Daridorexant?
Daridorexant is a medication used to treat insomnia, which is difficulty falling or staying asleep. It belongs to a class of medicines called dual orexin receptor antagonists, which work by blocking certain brain signals that keep you awake. This helps you fall asleep faster and stay asleep longer. Daridorexant is usually taken as part of a treatment plan that includes good sleep habits.
Directions for Use
For how long do I take Daridorexant?
Daridorexant is usually taken long-term for managing insomnia, which is difficulty falling or staying asleep. You'll typically take it every day as prescribed by your doctor. How long you'll need this medication depends on your response, any side effects, and changes in your overall health. Always talk with your doctor before changing or stopping your Daridorexant treatment.
How do I dispose of Daridorexant?
Dispose of unused Daridorexant by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Daridorexant?
Take Daridorexant as prescribed by your doctor, usually once daily in the evening. It should be taken without food to help it work best. Do not crush or chew the tablet. If you miss a dose, take it as soon as you remember unless it's close to your next dose. In that case, skip the missed dose and continue your regular schedule. Avoid alcohol while taking this medication, as it can increase side effects.
How long does it take for Daridorexant to start working?
Daridorexant starts working the first night you take it, helping you fall asleep faster. However, it may take a few days to notice the full benefits, such as improved sleep quality and duration. Individual factors like age, overall health, and sleep habits can affect how quickly you see results. Take it exactly as prescribed for the best outcomes.
How should I store Daridorexant?
Store Daridorexant at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms. Always keep Daridorexant out of children's reach to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Daridorexant?
The usual starting dose of Daridorexant for adults is 25 mg once daily in the evening. Your doctor may adjust your dose based on your response and any side effects. The maximum recommended dose is 50 mg per day. Always follow your doctor's specific dosing instructions for your personal health needs. Special populations, such as the elderly, may require dose adjustments.
Warnings and Precautions
Can Daridorexant be taken safely while breastfeeding?
The safety of Daridorexant while breastfeeding is not well-established. It's unclear if the medication passes into breast milk. Discuss with your doctor if you're breastfeeding or planning to breastfeed. They can help determine the safest treatment options for you and your baby.
Can Daridorexant be taken safely while pregnant?
The safety of Daridorexant during pregnancy is not well-established. It's important to discuss with your doctor if you're pregnant or planning to become pregnant. They can help determine the safest way to manage your condition during this time and create a treatment plan that protects both you and your baby.
Can I take Daridorexant with other prescription drugs?
Daridorexant may interact with other medications that cause drowsiness, such as sedatives or certain antidepressants. These interactions can increase drowsiness and dizziness. Always inform your doctor about all the medications you take to avoid potential interactions. They can help adjust your treatment plan to ensure safety and effectiveness.
Does Daridorexant have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Daridorexant include drowsiness and dizziness. Serious side effects are rare but can include allergic reactions. If you experience any new or worsening symptoms, contact your doctor. They can help determine if the symptoms are related to the medication and advise on the best course of action.
Does Daridorexant have any safety warnings?
Yes, Daridorexant has safety warnings. It may cause drowsiness, so avoid activities requiring alertness, like driving, until you know how it affects you. Alcohol can increase drowsiness and should be avoided. Not adhering to these warnings can lead to accidents or injuries. Always follow your doctor's advice and report any unusual symptoms.
Is Daridorexant addictive?
Daridorexant is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. However, always use it as prescribed by your doctor. If you have concerns about medication dependence, discuss them with your healthcare provider to ensure safe use.
Is Daridorexant safe for the elderly?
Elderly individuals may be more sensitive to the effects of Daridorexant, such as drowsiness and dizziness. These side effects can increase the risk of falls. It's important for elderly patients to use this medication under close supervision by a healthcare provider. Regular monitoring and dose adjustments may be necessary to ensure safety.
Is it safe to drink alcohol while taking Daridorexant?
It's best to avoid alcohol while taking Daridorexant. Alcohol can increase drowsiness and dizziness, which are side effects of the medication. This combination may impair your ability to perform tasks that require alertness, like driving. Talk with your doctor about alcohol use while taking Daridorexant for personalized advice.
Is it safe to exercise while taking Daridorexant?
You can exercise while taking Daridorexant, but be cautious. The medication may cause drowsiness or dizziness, which could affect your balance and coordination. To exercise safely, avoid strenuous activities until you know how the medication affects you. If you feel dizzy or lightheaded, stop exercising and rest. Consult your doctor if you have concerns.
Is it safe to stop Daridorexant?
It's important to talk with your doctor before stopping Daridorexant. Stopping suddenly may cause your symptoms to return or worsen. Your doctor might suggest gradually reducing your dose to avoid any potential issues. They will help you make any medication changes safely to protect your health.
What are the most common side effects of Daridorexant?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Daridorexant include drowsiness and dizziness. These effects vary from person to person. If you notice new symptoms after starting Daridorexant, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Daridorexant?
Don't take Daridorexant if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Use caution if you have liver problems, as it may affect how the medication works. Always consult your doctor about any concerns or conditions before starting Daridorexant.
