Cyproterone
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
No
Summary
Cyproterone is used to treat prostate cancer, which is a type of cancer affecting the prostate gland in men, and severe acne, which refers to a skin condition causing pimples and inflammation. It may also be prescribed for other conditions as determined by your doctor.
Cyproterone works by blocking male hormones called androgens, which are responsible for stimulating cancer cell growth and acne. By reducing the effects of these hormones, cyproterone helps slow down cancer progression and improve skin conditions.
Cyproterone is typically taken as a tablet, once or twice daily, with or without food. The usual starting dose for adults ranges from 50 mg to 100 mg per day, depending on the condition being treated. Always follow your doctor's dosing instructions.
Common side effects of cyproterone include fatigue, which means feeling very tired, weight changes, and mood swings, which refer to sudden changes in emotions. These effects are usually mild to moderate and should be discussed with your doctor if they occur.
Cyproterone can cause liver damage, so regular liver tests are necessary. It may increase the risk of blood clots, which are clumps of blood that can block blood vessels. Do not use if you have liver disease, a history of blood clots, or are pregnant.
Indications and Purpose
How does cyproterone work?
Cyproterone works by blocking the effects of male hormones, which are called androgens, in the body. This action helps slow the growth of prostate cancer cells and reduces acne symptoms. Think of it like turning down the volume on a radio; cyproterone lowers the "volume" of androgens, reducing their effects on the body. This makes it effective for conditions like prostate cancer and severe acne.
Is cyproterone effective?
Cyproterone is effective for treating conditions like prostate cancer and severe acne. It works by blocking the effects of male hormones, which can slow the growth of cancer cells and reduce acne symptoms. Clinical studies support its effectiveness in these conditions. Always follow your doctor's advice to achieve the best results with cyproterone.
What is cyproterone?
Cyproterone is a medication that belongs to the class of anti-androgens, which block male hormones. It is primarily used to treat prostate cancer and severe acne. By reducing the effects of male hormones, cyproterone helps slow cancer growth and improve acne symptoms. It may also be used for other conditions as determined by your doctor.
Directions for Use
For how long do I take cyproterone?
Cyproterone is usually taken long-term for chronic conditions like prostate cancer. The duration depends on your response to treatment and any side effects. Your doctor will guide you on how long to continue cyproterone based on your health needs. Always talk with your doctor before changing or stopping your cyproterone treatment.
How do I dispose of cyproterone?
Dispose of cyproterone by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options aren't available, mix the medication with an undesirable substance like used coffee grounds, seal it in a plastic bag, and throw it in the trash. This helps prevent harm to people and the environment.
How do I take cyproterone?
Take cyproterone exactly as your doctor prescribes. It's usually taken once or twice daily, with or without food. Swallow the tablets whole; do not crush them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Avoid alcohol while taking cyproterone, as it can increase side effects. Always follow your doctor's specific instructions regarding diet and fluid intake while on this medication.
How long does it take for cyproterone to start working?
Cyproterone starts working in your body shortly after you take it, but noticeable effects may take weeks. For prostate cancer, symptom improvement might be seen in a few weeks. For acne, clearer skin may take several months. How quickly cyproterone works can depend on your condition and overall health. Follow your doctor's instructions for the best results.
How should I store cyproterone?
Store cyproterone at room temperature, away from moisture and light. Keep it in a tightly closed container. Do not store it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep cyproterone out of reach of children to prevent accidental ingestion. Check expiration dates regularly and dispose of expired medication properly.
What is the usual dose of cyproterone?
The usual starting dose of cyproterone for adults is 50 mg to 100 mg once or twice daily, depending on the condition being treated. Your doctor may adjust the dose based on your response and any side effects. The maximum recommended dose is 300 mg per day. Dose adjustments may be necessary for elderly patients or those with specific health conditions. Always follow your doctor's dosing instructions for your health needs.
Warnings and Precautions
Can cyproterone be taken safely while breastfeeding?
Cyproterone is not recommended while breastfeeding. It can pass into breast milk and may affect the baby. If you're breastfeeding or planning to, discuss safer medication options with your doctor. They can help you choose treatments that allow you to nurse your baby safely.
Can cyproterone be taken safely while pregnant?
Cyproterone is not safe during pregnancy. It can harm the developing baby, leading to birth defects. If you are pregnant or planning to become pregnant, talk to your doctor about alternative treatments. They can help create a safe treatment plan that protects both you and your baby.
Can I take cyproterone with other prescription drugs?
Cyproterone can interact with other medications, increasing the risk of side effects or reducing effectiveness. Major interactions include anticoagulants, which can increase bleeding risk, and other hormone therapies, which can affect hormone levels. Always inform your doctor about all medications you take to avoid potential interactions and ensure safe treatment.
Does cyproterone have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of cyproterone include fatigue, weight changes, and mood swings. Serious side effects can include liver damage and blood clots. If you notice any new or worsening symptoms, contact your doctor immediately. They can help determine if these symptoms are related to cyproterone and advise on the best course of action.
Does cyproterone have any safety warnings?
Yes, cyproterone has important safety warnings. It can cause liver damage, so regular liver function tests are necessary. It may also increase the risk of blood clots, which can lead to serious conditions like deep vein thrombosis or pulmonary embolism. If you experience symptoms like sudden chest pain, shortness of breath, or swelling in your legs, seek medical help immediately. Always adhere to your doctor's safety advice while taking cyproterone.
Is cyproterone addictive?
Cyproterone is not considered addictive or habit-forming. It does not cause physical or psychological dependence. However, always use it as prescribed by your doctor. If you have concerns about medication dependence, discuss them with your healthcare provider. They can provide reassurance and guidance on the safe use of cyproterone.
Is cyproterone safe for the elderly?
Elderly individuals are more vulnerable to the side effects of cyproterone, such as liver damage and blood clots. These risks require careful monitoring. Cyproterone can be used safely in the elderly with regular check-ups and dose adjustments as needed. Always consult your doctor to ensure the benefits outweigh the risks for elderly patients.
Is it safe to drink alcohol while taking cyproterone?
It's best to avoid alcohol while taking cyproterone. Alcohol can increase the risk of liver damage and worsen side effects like dizziness. If you choose to drink, limit your intake and watch for symptoms like nausea or dizziness. Talk with your doctor about alcohol use while on cyproterone for personalized advice.
Is it safe to exercise while taking cyproterone?
You can exercise while taking cyproterone, but be mindful of side effects like fatigue or dizziness. These might affect your exercise capacity. To exercise safely, stay hydrated and listen to your body. If you feel dizzy or unusually tired, slow down or stop and rest. Consult your doctor if you have concerns about exercising while on cyproterone.
Is it safe to stop cyproterone?
Stopping cyproterone suddenly can lead to a return of symptoms it was managing. It's important to consult your doctor before stopping. They may suggest gradually reducing the dose to avoid any potential withdrawal effects. Your doctor will guide you on how to safely discontinue cyproterone if needed, ensuring your health condition remains stable.
What are the most common side effects of cyproterone?
Side effects are unwanted reactions to a medication. Common side effects of cyproterone include fatigue, weight gain, and mood changes. These effects vary from person to person. If you experience new symptoms after starting cyproterone, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication.
Who should avoid taking cyproterone?
Do not use cyproterone if you have liver disease, a history of blood clots, or are pregnant. These are absolute contraindications due to severe risks. Use caution if you have diabetes or depression, as these are relative contraindications. Always discuss your medical history with your doctor before starting cyproterone to ensure it's safe for you.
