Cycloserine

Escherichia coli Infections , Gaucher Disease ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

YES

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Known Teratogen

No

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Pharmaceutical Class

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Controlled Drug Substance

No

Summary

  • Cycloserine is used to treat tuberculosis, which is a bacterial infection affecting the lungs. It helps control the infection by stopping the growth of bacteria. It's often used with other medications to effectively treat tuberculosis.

  • Cycloserine works by inhibiting the growth of bacteria, which means it stops bacteria from multiplying. It interferes with the bacteria's ability to build their cell walls, which are essential for their survival.

  • The usual starting dose for adults is 250 mg taken twice daily. Your doctor may adjust the dose based on your response and any side effects. The maximum recommended dose is 1,000 mg per day. It's taken orally, which means by mouth.

  • Common side effects include dizziness, headache, and irritability, which means feeling easily annoyed or angry. These effects can vary from person to person. If you experience new symptoms, talk with your doctor.

  • Cycloserine should not be used if you have a history of seizures, which are sudden, uncontrolled electrical disturbances in the brain, or severe mental health issues. Always inform your doctor of your medical history before starting Cycloserine.

Indications and Purpose

How does Cycloserine work?

Cycloserine works by inhibiting the growth of bacteria, helping to control infections like tuberculosis, which is a bacterial infection affecting the lungs. It interferes with the bacteria's ability to build their cell walls, which are essential for their survival. Think of it like removing the bricks from a wall, causing it to collapse. This action helps your body fight the infection more effectively. Cycloserine is often used in combination with other medications to treat tuberculosis.

Is Cycloserine effective?

Cycloserine is effective in treating tuberculosis, which is a bacterial infection that primarily affects the lungs. It works by inhibiting the growth of bacteria, helping to control the infection. Clinical studies support its effectiveness in treating tuberculosis, especially when used in combination with other medications. It's important to take Cycloserine exactly as prescribed by your doctor to achieve the best results. Regular monitoring by your healthcare provider ensures the medication is working effectively for your condition.

What is Cycloserine?

Cycloserine is an antibiotic used to treat tuberculosis, which is a bacterial infection affecting the lungs. It belongs to the class of medications called antitubercular agents. Cycloserine works by inhibiting the growth of bacteria, helping to control the infection. It's often used in combination with other medications to effectively treat tuberculosis. Your doctor will determine the best treatment plan for you based on your specific health needs and the severity of the infection.

Directions for Use

For how long do I take Cycloserine?

Cycloserine is usually used for short-term treatment of tuberculosis, which is a bacterial infection affecting the lungs. The duration of use depends on your specific condition and response to treatment. Your doctor will determine how long you need to take Cycloserine based on your health needs. It's important to complete the full course of treatment as prescribed to ensure the infection is fully treated. Always talk with your doctor before changing or stopping your Cycloserine treatment.

How do I dispose of Cycloserine?

To dispose of Cycloserine, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.

How do I take Cycloserine?

Take Cycloserine exactly as prescribed by your doctor. It's usually taken twice daily, once in the morning and once in the evening. You can take it with or without food. Swallow the capsules whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.

How long does it take for Cycloserine to start working?

Cycloserine starts working in your body shortly after you take it, but you may not notice all the benefits right away. For tuberculosis, which is a bacterial infection affecting the lungs, it may take several weeks to see significant improvement in symptoms. The full therapeutic effect can take months, depending on the severity of the infection and your response to treatment. It's important to take Cycloserine exactly as prescribed for the best results.

How should I store Cycloserine?

Store Cycloserine at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Do not store it in humid places like bathrooms, where moisture in the air could affect how well the medication works. Always store Cycloserine out of children's reach to prevent accidental swallowing. Remember to check the expiration date regularly and properly dispose of any unused or expired medication.

What is the usual dose of Cycloserine?

The usual starting dose of Cycloserine for adults is 250 mg twice daily. Your doctor may adjust the dose based on your response and any side effects. The maximum recommended dose is 1,000 mg per day. For children or elderly patients, dose adjustments may be necessary, and careful monitoring is required. Always follow your doctor's specific dosing instructions for your health needs. Do not change your dose without consulting your healthcare provider.

Warnings and Precautions

Can Cycloserine be taken safely while breastfeeding?

The safety of Cycloserine while breastfeeding is not well-established. It's unclear if the medication passes into breast milk or affects the breastfed infant. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest treatment options. They can help determine if Cycloserine is appropriate for you and your baby. Your doctor will consider the benefits and risks and may suggest alternative medications that are safer during breastfeeding.

Can Cycloserine be taken safely while pregnant?

The safety of Cycloserine during pregnancy is not well-established. Limited evidence makes it difficult to provide definitive advice. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options. They can help create a plan that protects both you and your baby. Your doctor will weigh the benefits and risks of using Cycloserine during pregnancy based on your specific health needs.

Can I take Cycloserine with other prescription drugs?

Cycloserine can interact with other medications, increasing the risk of side effects. For example, taking it with alcohol or other medications that affect the nervous system can increase the risk of seizures, which are sudden, uncontrolled electrical disturbances in the brain. Always inform your doctor about all the medications you are taking to prevent interactions. Your doctor can provide guidance on safe use and may adjust your treatment plan to minimize the risk of interactions.

Does Cycloserine have adverse effects?

Adverse effects are unwanted reactions to a medication. Cycloserine can cause adverse effects like dizziness, headache, and irritability. These effects vary in frequency and severity. Serious side effects include seizures and mental health changes, which require immediate medical attention. If you notice any new or worsening symptoms while taking Cycloserine, contact your doctor. They can help determine if the medication is the cause and adjust your treatment plan as needed to ensure your safety.

Does Cycloserine have any safety warnings?

Yes, Cycloserine has important safety warnings. It can cause serious side effects like seizures, which are sudden, uncontrolled electrical disturbances in the brain, and mental health changes, such as depression or anxiety. Not adhering to these warnings can lead to severe consequences, including worsening of these conditions. Always inform your doctor of any history of seizures or mental health issues before starting Cycloserine. If you experience any concerning symptoms, seek medical attention immediately.

Is Cycloserine addictive?

Cycloserine is not considered addictive or habit-forming. It does not cause physical or psychological dependence. However, it's important to take it exactly as prescribed by your doctor. If you have concerns about medication dependence, discuss them with your healthcare provider. They can provide reassurance and guidance on how to use Cycloserine safely and effectively. Always follow your doctor's instructions and do not stop taking the medication without consulting them first.

Is Cycloserine safe for the elderly?

Elderly individuals may be more vulnerable to the side effects of Cycloserine, such as dizziness and mental health changes. These effects can be more pronounced in older adults due to age-related changes in the body. It's important for elderly patients to be closely monitored while taking Cycloserine. Your doctor will assess the risks and benefits and may adjust the dose accordingly. Always inform your healthcare provider of any new or worsening symptoms while on this medication.

Is it safe to drink alcohol while taking Cycloserine?

It's best to avoid alcohol while taking Cycloserine. Alcohol can increase the risk of side effects like dizziness and seizures, which are sudden, uncontrolled electrical disturbances in the brain. Drinking alcohol can also worsen mental health changes, such as depression or anxiety. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like dizziness or mood changes. Talk with your doctor about alcohol use while taking Cycloserine for personalized advice.

Is it safe to exercise while taking Cycloserine?

You can exercise while taking Cycloserine, but be cautious. This medication can cause dizziness and fatigue, which might affect your ability to exercise safely. If you feel dizzy or unusually tired during physical activity, slow down or stop and rest. Drink plenty of water to stay hydrated. Avoid strenuous activities or high-impact sports until you know how Cycloserine affects you. If you have concerns about exercising while on this medication, talk with your doctor for personalized advice.

Is it safe to stop Cycloserine?

Stopping Cycloserine suddenly can be risky. It's usually used for short-term treatment of infections, and stopping early can lead to treatment failure or resistance. If you need to stop taking Cycloserine, always consult your doctor first. They might suggest a gradual reduction in dose or an alternative treatment to ensure your condition remains under control. Your doctor will help you make any medication changes safely to protect your health.

What are the most common side effects of Cycloserine?

Side effects are unwanted reactions to a medication. Common side effects of Cycloserine include dizziness, headache, and irritability. These effects can vary from person to person. If you experience new symptoms after starting Cycloserine, they might be temporary or unrelated to the medication. It's important to talk with your doctor before stopping any medication. They can help determine if the side effects are related to Cycloserine and suggest ways to manage them.

Who should avoid taking Cycloserine?

Cycloserine should not be used if you have a history of seizures or severe mental health issues, as it can worsen these conditions. These are considered absolute contraindications. Relative contraindications include kidney problems, which require careful monitoring. Always inform your doctor of your medical history before starting Cycloserine. They can assess the risks and benefits and determine if this medication is appropriate for you. Your doctor will provide guidance on safe use based on your health needs.