Cilazapril
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Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Angiotensin Converting Enzyme Inhibitor
Controlled Drug Substance
No
Summary
Cilazapril is used to treat high blood pressure, which is also known as hypertension. It helps reduce the risk of heart attack, stroke, and kidney problems. Cilazapril may also be used for heart failure, which is when the heart can't pump blood effectively.
Cilazapril is an ACE inhibitor, which works by blocking a substance in the body that causes blood vessels to tighten. This action relaxes the blood vessels, allowing blood to flow more easily, which lowers blood pressure.
The usual starting dose of cilazapril for adults is 2.5 mg once daily. Your doctor may adjust the dose based on your response and needs, with a maximum recommended dose of 5 mg daily. Take cilazapril once daily, usually in the morning, with or without food.
Common side effects of cilazapril include dizziness, cough, and fatigue, which is a feeling of tiredness. These effects vary from person to person. If you notice new symptoms after starting cilazapril, they might be temporary or unrelated to the medication.
Cilazapril can cause a severe drop in blood pressure, especially when starting treatment or increasing the dose. It can also increase potassium levels, leading to hyperkalemia, which is a high level of potassium in the blood. Avoid if allergic to cilazapril or its ingredients.
Indications and Purpose
How does cilazapril work?
Cilazapril is an ACE inhibitor, which works by blocking a substance in the body that causes blood vessels to tighten. This action relaxes the blood vessels, allowing blood to flow more easily, which lowers blood pressure. Think of it like opening a valve to let water flow through a pipe more smoothly. By reducing blood pressure, cilazapril helps decrease the risk of heart attack, stroke, and kidney problems. This makes it effective for managing high blood pressure.
Is cilazapril effective?
Cilazapril is effective in treating high blood pressure, which is also known as hypertension. It works by relaxing blood vessels, allowing blood to flow more easily, which lowers blood pressure. Clinical studies show cilazapril significantly reduces blood pressure in patients with hypertension. Lowering blood pressure helps reduce the risk of heart attack, stroke, and kidney problems. Always follow your doctor's instructions and attend regular check-ups to monitor your blood pressure and ensure cilazapril is working effectively for you.
What is cilazapril?
Cilazapril is a medication used to treat high blood pressure, also known as hypertension. It belongs to a class of drugs called ACE inhibitors, which work by relaxing blood vessels to lower blood pressure. This helps improve blood flow and reduces the risk of heart attack, stroke, and kidney problems. Cilazapril is usually used alone or in combination with other medications to manage blood pressure effectively. Always follow your doctor's instructions when taking cilazapril.
Directions for Use
For how long do I take cilazapril?
Cilazapril is usually a long-term medication for managing high blood pressure, which is a chronic condition. You'll typically take cilazapril every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your blood pressure to rise, increasing the risk of heart attack or stroke. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your cilazapril treatment.
How do I dispose of cilazapril?
If you can, bring unused cilazapril to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so it doesn't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take cilazapril?
Take cilazapril once daily, usually in the morning, with or without food. Swallow the tablet whole; do not crush it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Avoid alcohol while on cilazapril, as it can increase side effects. Always follow your doctor's specific instructions regarding diet and fluid intake while taking this medication.
How long does it take for cilazapril to start working?
Cilazapril begins working in your body shortly after you take it, but it may take several weeks to achieve its full therapeutic effect. You might notice some improvement in blood pressure within a few days, but more significant changes typically take a few weeks. How quickly cilazapril works can depend on your overall health and other medications you may be taking. Regular monitoring of your blood pressure is important to see how well cilazapril is working for you. Always take it as prescribed for the best results.
How should I store cilazapril?
Store cilazapril tablets at room temperature, away from moisture and light. Keep the medication in a tightly closed container to protect it from damage. Don't store your medicine in humid places like bathrooms, where moisture in the air could affect how well the medication works. Always store cilazapril out of children's reach to prevent accidental swallowing. Remember to check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of cilazapril?
The usual starting dose of cilazapril for adults is 2.5 mg once daily. Your doctor may adjust the dose based on your response and needs, with a maximum recommended dose of 5 mg daily. Dose adjustments may be necessary for elderly patients or those with kidney problems. Always follow your doctor's specific dosing instructions for your health needs. Do not change your dose without consulting your healthcare provider.
Warnings and Precautions
Can cilazapril be taken safely while breastfeeding?
Cilazapril is not recommended while breastfeeding. We don't have much information about whether this medication passes into human breast milk. However, it may affect the baby's developing kidneys, which are organs that filter waste from the blood. While we don't have specific reports of harm to breastfed babies from cilazapril, we can't rule out potential risks. If you're taking cilazapril and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can cilazapril be taken safely while pregnant?
Cilazapril is not recommended during pregnancy, especially in the second and third trimesters. It can harm the developing baby, leading to kidney problems or other complications. We don't have much information about cilazapril use in pregnant women, but it's important to manage blood pressure during pregnancy to avoid risks to both mother and baby. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your blood pressure during this important time.
Can I take cilazapril with other prescription drugs?
Cilazapril can interact with other medications, increasing the risk of side effects or reducing effectiveness. Diuretics, which are water pills, can increase the risk of low blood pressure. Potassium supplements or potassium-sparing diuretics can lead to high potassium levels, causing heart problems. Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce cilazapril's effectiveness in lowering blood pressure. Always inform your doctor about all medications you take to avoid interactions and ensure your treatment is safe and effective.
Does cilazapril have adverse effects?
Adverse effects are unwanted reactions to a medication. Cilazapril can cause dizziness, cough, and fatigue, which are common side effects. Serious adverse effects include angioedema, which is swelling under the skin, and hyperkalemia, which is high potassium levels. If you experience severe side effects, seek medical attention immediately. Always inform your doctor about any new or worsening symptoms while taking cilazapril. They can help determine if the medication is the cause and adjust your treatment if necessary.
Does cilazapril have any safety warnings?
Yes, cilazapril has important safety warnings. It can cause a severe drop in blood pressure, especially when starting treatment or increasing the dose. This may lead to dizziness or fainting. Cilazapril can also increase potassium levels, leading to hyperkalemia, which is a high level of potassium in the blood. This can cause heart problems. If you experience swelling of the face, lips, or throat, seek emergency help, as this may indicate an allergic reaction. Always follow your doctor's advice and report any unusual symptoms.
Is cilazapril addictive?
Cilazapril is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Cilazapril works by relaxing blood vessels to lower blood pressure, which does not affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, cilazapril does not carry this risk while managing your blood pressure.
Is cilazapril safe for the elderly?
Elderly individuals are more vulnerable to the safety risks of medications like cilazapril. They may experience more pronounced side effects, such as dizziness or low blood pressure, which can increase the risk of falls. Cilazapril is generally safe for the elderly, but careful monitoring is needed. Dose adjustments may be necessary based on kidney function and overall health. Regular check-ups with a doctor are important to ensure cilazapril is working effectively and safely for elderly patients.
Is it safe to drink alcohol while taking cilazapril?
It's best to avoid alcohol while taking cilazapril. Drinking alcohol can increase the risk of side effects like dizziness or low blood pressure. Alcohol can also interfere with the effectiveness of cilazapril in controlling blood pressure. If you do choose to drink occasionally, limit how much alcohol you consume and watch for warning signs like dizziness or fainting. Talk with your doctor about alcohol use while taking cilazapril to get personalized advice based on your specific health situation.
Is it safe to exercise while taking cilazapril?
You can exercise while taking cilazapril, but keep a few things in mind. This medication can cause dizziness or lightheadedness, especially when you stand up quickly. These feelings might be more noticeable during exercise. To exercise safely, start slowly and gradually increase your activity level. Drink plenty of water before, during, and after physical activity. Watch for signs of dizziness or unusual fatigue. If you notice these symptoms, slow down or stop exercising and rest. Check with your doctor if you have concerns.
Is it safe to stop cilazapril?
Stopping cilazapril suddenly can cause your blood pressure to rise, increasing the risk of heart attack or stroke. Cilazapril is usually used long-term for managing high blood pressure. Always talk with your doctor before stopping cilazapril. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
What are the most common side effects of cilazapril?
Side effects are unwanted reactions that can occur with medication use. Common side effects of cilazapril include dizziness, cough, and fatigue. These effects vary from person to person. If you notice new symptoms after starting cilazapril, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication. They can help determine if cilazapril is the cause and suggest ways to manage side effects while continuing your treatment.
Who should avoid taking cilazapril?
Do not take cilazapril if you're allergic to it or its ingredients. Serious allergic reactions, which cause rash, hives, or swelling that makes breathing difficult, require immediate medical help. Cilazapril is not recommended for people with a history of angioedema, which is swelling under the skin, related to previous ACE inhibitor use. It should be used with caution in patients with kidney problems or those taking potassium supplements. Always consult your doctor about these concerns.
