Chlorpromazine
Hiccup, Acute Intermittent Porphyria ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
Phenothiazine
Controlled Drug Substance
NO
Chlorpromazine
Learn more about this medicine -
Click HereSummary
Chlorpromazine is used to treat various conditions including schizophrenia, bipolar disorder, severe anxiety, and certain behavioral disorders. It also helps manage nausea, vomiting, and severe hiccups.
Chlorpromazine works by blocking certain chemicals in the brain, like dopamine, to reduce overactivity. This helps stabilize mood and behavior.
The usual daily dose for adults ranges from 25 mg three times a day, gradually increasing to 400 mg daily or 500 mg daily, potentially increasing to 2000 mg daily. However, exceeding 1000 mg daily offers little additional therapeutic benefit. Dosage should be adjusted based on individual needs and response. It is taken orally.
Common side effects include drowsiness, dry mouth, constipation, and dizziness. Rarely, it can cause low blood pressure or movement issues. Serious effects include heart problems and neuroleptic malignant syndrome.
Avoid Chlorpromazine if you have liver disease, low blood pressure, or severe heart conditions. It's not recommended during pregnancy or breastfeeding unless prescribed by a doctor. Also, it's crucial to avoid driving or operating heavy machinery until you know how it affects you due to its sedative effects.
Indications and Purpose
How does Chlorpromazine work?
Chlorpromazine blocks certain chemicals in the brain like dopamine to reduce overactivity, helping to stabilize mood and behavior.
How does one know if Chlorpromazine is working?
Improvement in symptoms such as reduced hallucinations, stabilized mood, and decreased agitation indicates that the medicine is working. Regular follow-ups help assess progress.
Is Chlorpromazine effective?
Yes, studies and patient experience show that chlorpromazine effectively reduces symptoms of psychosis and mood disorders when used as prescribed.
What is Chlorpromazine?
Chlorpromazine is a medication used to treat various conditions, including schizophrenia, bipolar disorder, nausea, and hiccups. It works by affecting the activity of certain substances in the brain and body. The dosage of chlorpromazine varies depending on the condition being treated and is typically taken 2-4 times daily. However, it can be taken more frequently for nausea or hiccups. It's important to follow your doctor's instructions carefully when taking chlorpromazine.
What is Chlorpromazine used for?
Chlorpromazine treats schizophrenia, bipolar disorder, severe anxiety, and certain behavioral disorders. It also manages nausea, vomiting, and severe hiccups in some cases.
Directions for Use
For how long do I take Chlorpromazine?
The duration of treatment varies. Some conditions require long-term use, while others may only need short-term therapy. Follow your doctor’s guidance.
How do I take Chlorpromazine?
Chlorpromazine is a medication used to treat various conditions, such as nausea, vomiting, pre-surgical nervousness, and hiccups. It's taken orally, and the dosage and frequency depend on the condition being treated. For nausea and vomiting, it's taken every 4-6 hours as needed. For pre-surgical nervousness, it's taken 2-3 hours before surgery. For hiccups, it's taken 3-4 times daily for up to 3 days. It's important to follow your doctor's instructions and take it at the same times each day if you're taking it regularly.
How long does it take for Chlorpromazine to start working?
Chlorpromazine may start to show some effects within hours, but it can take several days to weeks for full benefits, especially for mental health conditions.
How should I store Chlorpromazine?
Store chlorpromazine at room temperature, away from direct sunlight and moisture. Keep out of reach of children and pets.
What is the usual dose of Chlorpromazine?
The usual daily dose of this medicine for adults ranges from 25 mg three times a day, gradually increasing to 400 mg daily, or 500 mg daily, potentially increasing to 2000 mg daily. However, exceeding 1000 mg daily offers little additional therapeutic benefit. Dosage should be adjusted based on individual needs and response.
Warnings and Precautions
Can Chlorpromazine be taken safely while breastfeeding?
This medicine passes into breast milk and may harm the baby. Consult your doctor for alternatives while breastfeeding.
Can Chlorpromazine be taken safely while pregnant?
Chlorpromazine is not generally recommended during pregnancy unless necessary. It may affect the baby. Discuss options with your doctor if you are pregnant.
Can I take Chlorpromazine with other prescription drugs?
Chlorpromazine interacts with several drugs, including sedatives, antihypertensives, and certain antidepressants. Always share your medication list with your doctor.
Can I take Chlorpromazine with vitamins or supplements?
Inform your doctor about all vitamins or supplements you're using. Some, like St. John’s Wort, may interact with chlorpromazine and reduce its effectiveness.
Is Chlorpromazine safe for the elderly?
Elderly patients are more prone to side effects like sedation and low blood pressure. Dose adjustments and close monitoring are recommended.
Is it safe to drink alcohol while taking Chlorpromazine?
Alcohol should be avoided, as it increases drowsiness and dizziness, potentially leading to dangerous side effects. Discuss your drinking habits with your doctor.
Is it safe to exercise while taking Chlorpromazine?
Yes, but avoid strenuous activity that may worsen side effects like dizziness or low blood pressure. Stay hydrated and avoid overheating during exercise.
Who should avoid taking Chlorpromazine?
Avoid chlorpromazine if you have liver disease, low blood pressure, or severe heart conditions. It’s not recommended during pregnancy or breastfeeding unless prescribed by a doctor.
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