Cevimeline
Xerostomia
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Cholinergic Receptor Agonist
Controlled Drug Substance
No
cevimeline
Summary
Cevimeline is used to treat dry mouth, which is a condition where the mouth doesn't produce enough saliva, often seen in Sjögren's syndrome, which is an autoimmune disorder causing dry eyes and mouth.
Cevimeline works by stimulating certain receptors, which are parts of cells that respond to signals, to increase saliva production, helping to relieve dry mouth symptoms.
The usual dose of Cevimeline for adults is 30 mg taken three times a day. It is taken orally, which means by mouth, and should be swallowed whole with food to reduce stomach upset.
Common side effects of Cevimeline include excessive sweating, which is more sweating than usual, nausea, which is feeling sick to your stomach, and a runny nose.
Cevimeline should not be used by people with uncontrolled asthma, which is a condition causing breathing problems, or narrow-angle glaucoma, which affects eye pressure. It can cause dehydration, so drink plenty of fluids.
Indications and Purpose
How does Cevimeline work?
Cevimeline works by stimulating certain receptors in your body to increase saliva production. Think of it like turning on a faucet to increase water flow. This helps relieve dry mouth symptoms, making it easier to speak, chew, and swallow. Cevimeline is particularly helpful for people with conditions like Sjögren's syndrome, where dry mouth is a common problem. By increasing saliva, it helps improve comfort and oral health.
Is Cevimeline effective?
Cevimeline is effective in treating dry mouth, especially in conditions like Sjögren's syndrome. It works by stimulating saliva production, which helps relieve symptoms of dry mouth. Clinical studies show that Cevimeline significantly improves saliva flow and reduces dry mouth symptoms. Most people using Cevimeline experience noticeable relief, making it an effective treatment for managing dry mouth associated with certain medical conditions.
What is Cevimeline?
Cevimeline is a medication used to treat dry mouth, especially in conditions like Sjögren's syndrome. It belongs to a class of drugs called cholinergic agonists, which work by stimulating saliva production. This helps relieve symptoms of dry mouth, making it easier to speak, chew, and swallow. Cevimeline is usually used as part of a comprehensive treatment plan, which may include other therapies to manage the underlying condition.
Directions for Use
For how long do I take Cevimeline?
Cevimeline is usually a long-term medication for managing dry mouth in conditions like Sjögren's syndrome. You'll typically take Cevimeline every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your symptoms to return. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Cevimeline treatment.
How do I dispose of Cevimeline?
Dispose of unused Cevimeline by taking it to a drug take-back program or collection site at a pharmacy or hospital. This ensures safe disposal without harming people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away.
How do I take Cevimeline?
Take Cevimeline as prescribed by your doctor, usually three times a day. It's best to take it with food to reduce the risk of stomach upset. Swallow the capsules whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses.
How long does it take for Cevimeline to start working?
Cevimeline begins working shortly after you take it, with noticeable effects on saliva production within an hour. However, the full therapeutic effect may take a few days to become apparent. Individual factors like your overall health and the severity of your condition can affect how quickly you notice improvements. Take Cevimeline exactly as prescribed for the best results, and talk with your doctor if you have any concerns about its effectiveness.
How should I store Cevimeline?
Store Cevimeline at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, where moisture could affect its effectiveness. Always store Cevimeline out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication to ensure safety.
What is the usual dose of Cevimeline?
The usual starting dose of Cevimeline for adults is 30 mg taken three times a day. Your doctor may adjust your dose based on your response and any side effects. The maximum recommended dose is 90 mg per day. Always follow your doctor's specific dosing instructions for your personal health needs. If you have any concerns about your dosage, discuss them with your healthcare provider.
Warnings and Precautions
Can Cevimeline be taken safely while breastfeeding?
The safety of Cevimeline while breastfeeding is not well-established. It's unclear if Cevimeline passes into breast milk or affects a breastfed infant. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest options for managing your condition. Your doctor can help determine if Cevimeline is appropriate or suggest alternative treatments that allow you to nurse your baby safely.
Can Cevimeline be taken safely while pregnant?
The safety of Cevimeline during pregnancy is not well-established. Limited information is available, and its effects on an unborn baby are not fully known. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby, considering the potential risks and benefits.
Can I take Cevimeline with other prescription drugs?
Cevimeline can interact with certain medications, increasing the risk of side effects. For example, it may interact with beta-blockers, which are used to treat high blood pressure, potentially affecting heart rate. It can also interact with other medications that affect saliva production. Always inform your doctor about all the medications you are taking to avoid potential interactions. Your doctor can help manage any interactions and adjust your treatment as needed.
Does Cevimeline have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Cevimeline include excessive sweating, nausea, and runny nose. These effects are usually mild. Serious side effects like difficulty breathing or chest pain are rare but require immediate medical attention. If you experience any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to Cevimeline and suggest appropriate actions.
Does Cevimeline have any safety warnings?
Cevimeline has important safety warnings. It can cause excessive sweating, which may lead to dehydration. Drink plenty of fluids to stay hydrated. Cevimeline may also cause blurred vision, especially at night. Be cautious when driving or operating machinery. If you experience severe side effects like difficulty breathing or chest pain, seek medical help immediately. Always follow your doctor's advice and report any new or worsening symptoms.
Is Cevimeline addictive?
Cevimeline is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Cevimeline works by stimulating saliva production and doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, Cevimeline doesn't carry this risk.
Is Cevimeline safe for the elderly?
Elderly individuals may be more sensitive to the side effects of Cevimeline, such as excessive sweating and dehydration. It's important for older adults to stay well-hydrated while taking this medication. Regular monitoring by a healthcare provider is recommended to ensure safety and effectiveness. If you have concerns about using Cevimeline as an older adult, discuss them with your doctor to tailor the treatment to your needs.
Is it safe to drink alcohol while taking Cevimeline?
It's best to avoid alcohol while taking Cevimeline. Alcohol can increase the risk of dehydration, which is a concern with Cevimeline as it can cause excessive sweating. Dehydration can worsen side effects like dizziness or low blood pressure. If you choose to drink occasionally, limit your alcohol intake and stay hydrated. Talk with your doctor about alcohol use while taking Cevimeline for personalized advice.
Is it safe to exercise while taking Cevimeline?
You can exercise while taking Cevimeline, but be cautious. This medication can cause excessive sweating, leading to dehydration. This might make you feel dizzy or lightheaded during exercise, especially in hot weather. To exercise safely, drink plenty of water before, during, and after physical activity. Watch for signs of dizziness or unusual fatigue. If you notice these symptoms, slow down or stop exercising and rest.
Is it safe to stop Cevimeline?
Cevimeline is usually taken for long-term management of dry mouth in conditions like Sjögren's syndrome. Stopping it suddenly may cause your symptoms to return. Always talk with your doctor before stopping Cevimeline. They might suggest gradually reducing your dose or switching to a different treatment to manage your condition safely. Your doctor will help you make any medication changes to protect your health.
What are the most common side effects of Cevimeline?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Cevimeline include excessive sweating, nausea, and runny nose. These effects vary from person to person and are usually mild. If you notice new symptoms after starting Cevimeline, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication to ensure your treatment remains effective.
Who should avoid taking Cevimeline?
Cevimeline should not be used if you have uncontrolled asthma, as it may worsen breathing problems. It's also contraindicated in people with narrow-angle glaucoma, which is a condition that affects eye pressure, and in those with allergies to the medication. Use caution if you have heart problems, as Cevimeline can affect heart rate. Always consult your doctor about any health concerns before starting Cevimeline.
