Cenobamate
Partial Epilepsies
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
NA
Controlled Drug Substance
YES
Summary
Cenobamate is used to treat partial-onset seizures, which are seizures that start in one part of the brain, in adults. It helps reduce the frequency of these seizures.
Cenobamate works by stabilizing electrical activity in the brain, which helps control seizures. It acts like a circuit breaker, preventing electrical overloads that can cause seizures.
Cenobamate is usually taken once daily by mouth, which means swallowing it. The starting dose is typically 12.5 mg, and it can be increased to a maximum of 400 mg per day based on your doctor's advice.
Common side effects of cenobamate include dizziness, which is feeling unsteady, drowsiness, which is feeling sleepy, and fatigue, which is feeling very tired. These effects vary among individuals.
Cenobamate can cause serious skin reactions and may increase the risk of suicidal thoughts. It is not recommended for people with severe liver problems. Always consult your doctor about any concerns.
Indications and Purpose
How does cenobamate work?
Cenobamate works by stabilizing electrical activity in the brain, which helps control seizures. It belongs to a class of medications called anticonvulsants. Think of it like a circuit breaker that prevents electrical overloads in your brain. This action reduces the frequency of seizures in people with partial-onset seizures.
Is cenobamate effective?
Cenobamate is effective in treating partial-onset seizures in adults. Clinical studies show it significantly reduces seizure frequency compared to placebo. This medication works by stabilizing electrical activity in the brain, which helps control seizures. If you have questions about its effectiveness for your condition, discuss them with your doctor.
What is cenobamate?
Cenobamate is a medication used to treat partial-onset seizures in adults. It belongs to the class of drugs known as anticonvulsants, which help stabilize electrical activity in the brain. This medication works by reducing the frequency of seizures. Cenobamate is typically used as an add-on therapy to other seizure medications.
Directions for Use
For how long do I take cenobamate?
Cenobamate is usually a long-term medication for managing partial-onset seizures. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your cenobamate treatment.
How do I dispose of cenobamate?
To dispose of cenobamate, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw most medicines in the trash at home. First, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take cenobamate?
Cenobamate is usually taken once daily. You can take it with or without food, but try to take it at the same time each day. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions for taking cenobamate.
How long does it take for cenobamate to start working?
Cenobamate begins working in your body shortly after you take it, but it may take several weeks to achieve its full therapeutic effect. The time it takes to notice improvements can vary based on individual factors like your condition and response to treatment. Take it exactly as prescribed for the best results.
How should I store cenobamate?
Store cenobamate at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of cenobamate?
The usual starting dose of cenobamate for adults is 12.5 mg once daily. Your doctor may gradually increase your dose based on your response and tolerance. The maximum recommended dose is 400 mg per day. Always follow your doctor's specific dosing instructions for your personal health needs. Dose adjustments may be necessary for special populations, such as the elderly.
Warnings and Precautions
Can cenobamate be taken safely while breastfeeding?
Cenobamate is not recommended while breastfeeding. We don't have much information about whether this medication passes into human breast milk. If you're taking cenobamate and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.
Can cenobamate be taken safely while pregnant?
Cenobamate is not recommended during pregnancy due to limited safety information. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. They can help create a treatment plan that protects both you and your baby.
Can I take cenobamate with other prescription drugs?
Cenobamate can interact with other medications, increasing the risk of side effects or reducing effectiveness. It may interact with drugs that affect the central nervous system, such as other seizure medications or sedatives. Always inform your doctor about all the medications you take to avoid potential interactions. Your doctor can help manage and adjust your treatment as needed.
Does cenobamate have adverse effects?
Adverse effects are unwanted reactions to a medication. Cenobamate can cause dizziness, drowsiness, and fatigue, which are common side effects. Serious adverse effects include skin reactions and suicidal thoughts. If you experience severe side effects, contact your doctor immediately. Always inform your healthcare provider about any new or worsening symptoms while taking cenobamate.
Does cenobamate have any safety warnings?
Cenobamate has important safety warnings. It can cause serious skin reactions, which may require immediate medical attention. It may also increase the risk of suicidal thoughts or behavior. If you experience mood changes, depression, or suicidal thoughts, contact your doctor right away. Cenobamate can cause dizziness and drowsiness, so avoid activities requiring alertness until you know how it affects you. Always follow your doctor's advice and report any concerning symptoms.
Is cenobamate addictive?
Cenobamate is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. However, always follow your doctor's instructions and don't change your dose or stop taking the medication without consulting your healthcare provider. If you have concerns about medication dependence, discuss them with your doctor.
Is cenobamate safe for the elderly?
Elderly individuals may be more sensitive to the side effects of cenobamate, such as dizziness and drowsiness. These effects can increase the risk of falls. It's important for elderly patients to be closely monitored by their healthcare provider while taking this medication. Dose adjustments may be necessary based on individual response and tolerance.
Is it safe to drink alcohol while taking cenobamate?
It's best to avoid alcohol while taking cenobamate. Alcohol can increase the risk of side effects like dizziness and drowsiness. If you do choose to drink occasionally, limit how much alcohol you consume and watch for warning signs like dizziness or trouble concentrating. Talk with your doctor about alcohol use while taking cenobamate to get personalized advice.
Is it safe to exercise while taking cenobamate?
You can exercise while taking cenobamate, but be cautious. This medication can cause dizziness and drowsiness, which might affect your balance and coordination. To exercise safely, start with light activities and see how your body responds. If you feel dizzy or lightheaded, stop exercising and rest. Talk with your doctor if you have concerns about your specific situation.
Is it safe to stop cenobamate?
Stopping cenobamate suddenly can cause serious problems, such as increased seizure activity. Always talk with your doctor before stopping cenobamate. They might suggest gradually reducing your dose to prevent withdrawal symptoms and keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
What are the most common side effects of cenobamate?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of cenobamate include dizziness, drowsiness, and fatigue. These effects vary from person to person. If you notice new symptoms after starting cenobamate, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking cenobamate?
Don't take cenobamate if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Cenobamate is not recommended for people with severe liver problems. Always consult your doctor about any concerns or conditions that might affect your use of cenobamate. They can help determine if this medication is safe for you.
