Candesartan
Hypertension, Left Ventricular Dysfunction ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
Definite
Pharmaceutical Class
Angiotensin 2 Receptor Blocker
Controlled Drug Substance
NO
Candesartan
Learn more about this medicine -
Click HereSummary
Candesartan is commonly used to treat high blood pressure and heart failure. It helps to lower blood pressure and reduce the risk of heart attacks and strokes. In heart failure, it improves symptoms and reduces hospitalizations.
Candesartan works by blocking the action of a substance in your body called angiotensin II, which causes blood vessels to tighten and narrow. By blocking this action, Candesartan helps to relax and widen your blood vessels, which lowers your blood pressure and improves blood flow.
For adults, the usual starting dose of Candesartan for high blood pressure is 16 mg once daily, which can be adjusted based on response. For children aged 1 to 17 years, the dose varies by weight. Always follow your doctor's specific dosing instructions.
Common side effects of Candesartan include headache, dizziness, and back pain. Serious side effects, though rare, include swelling of the face or throat, difficulty breathing, and decreased urination. If any serious side effects occur, seek medical attention immediately.
Candesartan should not be used during pregnancy and by those with known hypersensitivity to the drug. Caution is advised for patients with kidney or liver problems, and those taking potassium supplements due to the risk of high potassium levels in the blood.
Indications and Purpose
How does Candesartan work?
Candesartan works by blocking the action of angiotensin II, a natural substance that causes blood vessels to tighten. By preventing this action, Candesartan helps relax and widen blood vessels, which lowers blood pressure and makes it easier for the heart to pump blood.
How does one know if Candesartan is working?
The benefit of Candesartan is evaluated by regularly monitoring blood pressure to ensure it is within the target range. Regular follow-up appointments with your doctor will help assess the effectiveness of the medication and make any necessary adjustments to the dosage.
Is Candesartan effective?
Candesartan is proven effective in lowering blood pressure and reducing the risk of cardiovascular events like strokes and heart attacks. Clinical trials have shown it to be effective in treating hypertension and heart failure, often in combination with other medications, by blocking substances that tighten blood vessels.
What is Candesartan?
Candesartan is used to treat high blood pressure and heart failure. It belongs to a class of medications called angiotensin II receptor antagonists, which work by blocking substances that tighten blood vessels, allowing blood to flow more smoothly and the heart to pump more efficiently. This helps lower blood pressure and reduce the risk of cardiovascular events.
What is Candesartan used for?
Candesartan is indicated for the treatment of high blood pressure and heart failure. It helps lower blood pressure, reducing the risk of strokes, heart attacks, and kidney problems. It is also used to improve survival and reduce hospitalizations in people with heart failure.
Directions for Use
For how long do I take Candesartan?
Candesartan is typically used as a long-term treatment for high blood pressure and heart failure. It is important to continue taking it as prescribed by your doctor, even if you feel well, as it helps manage your condition over time.
How do I take Candesartan?
Candesartan can be taken with or without food, usually once or twice a day. It's important to take it at the same time each day to maintain an even level in your bloodstream. Avoid using salt substitutes containing potassium unless advised by your doctor.
How long does it take for Candesartan to start working?
Candesartan may start to lower blood pressure within the first two weeks of treatment, but it can take 4 to 6 weeks to notice the full benefit. It's important to continue taking the medication as prescribed, even if you feel well.
How should I store Candesartan?
Store Candesartan in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children. Do not store it in the bathroom. Dispose of unneeded medication through a take-back program, not by flushing it down the toilet.
What is the usual dose of Candesartan?
For adults, the usual starting dose of Candesartan is 16 mg once daily, which can be adjusted based on the patient's response, with a typical range of 8 mg to 32 mg per day. For children aged 1 to <17 years, the dose varies by weight: those under 50 kg typically start with 4 to 8 mg, while those over 50 kg may start with 8 to 16 mg, with adjustments as needed.
Warnings and Precautions
Can Candesartan be taken safely while breastfeeding?
It is not known if Candesartan passes into breast milk. Due to the potential for adverse effects on the nursing infant, a decision should be made to either discontinue breastfeeding or discontinue the medication, considering the importance of the drug to the mother.
Can Candesartan be taken safely while pregnant?
Candesartan is not recommended during pregnancy, especially in the second and third trimesters, as it can harm the developing fetus, potentially causing kidney problems, low blood pressure, and even death. If pregnancy is detected, discontinue use immediately and consult your doctor for alternative treatments.
Can I take Candesartan with other prescription drugs?
Candesartan can interact with NSAIDs, which may reduce its effectiveness and increase the risk of kidney problems. It can also interact with potassium supplements and diuretics, increasing the risk of hyperkalemia. Always inform your doctor of all medications you are taking to manage these interactions effectively.
Can I take Candesartan with vitamins or supplements?
Candesartan can interact with potassium supplements and salt substitutes containing potassium, increasing the risk of hyperkalemia. It's important to inform your doctor about all supplements you are taking to avoid potential interactions and manage your treatment safely.
Is Candesartan safe for the elderly?
Elderly patients may be more sensitive to the effects of Candesartan, particularly the risk of dizziness and lightheadedness. It's important for them to start on a lower dose and have their blood pressure monitored regularly. They should also be cautious when standing up quickly to avoid falls.
Is it safe to drink alcohol while taking Candesartan?
Drinking alcohol while taking Candesartan can enhance the blood pressure-lowering effect, potentially leading to dizziness or fainting. It's advisable to limit alcohol consumption and discuss with your doctor how much alcohol is safe for you while on this medication.
Is it safe to exercise while taking Candesartan?
Candesartan does not typically limit the ability to exercise. However, it may cause dizziness or lightheadedness, which could affect physical activity. If you experience these symptoms, take precautions during exercise and consult your doctor for advice tailored to your condition.
Who should avoid taking Candesartan?
Candesartan should not be used during pregnancy as it can harm the fetus. It's also contraindicated in patients with diabetes who are taking aliskiren. Patients with severe liver or kidney impairment should use it cautiously. Always inform your doctor of all medications and supplements you are taking to avoid interactions.
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