Cabotegravir

HIV Infections

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor

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Controlled Drug Substance

No

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Drug Ingredient

cabotegravir

Summary

  • Cabotegravir is used for preventing HIV infection, which is a virus that attacks the immune system, in people at high risk. It helps reduce the risk of acquiring HIV when used as part of a comprehensive prevention strategy.

  • Cabotegravir works by blocking an enzyme called integrase, which the HIV virus needs to multiply. This action helps prevent the virus from spreading in the body, reducing the risk of HIV infection.

  • Cabotegravir is usually given as an injection by a healthcare professional. The frequency and amount depend on your specific treatment plan, which your doctor will determine. Always follow your doctor's instructions for the best results.

  • Common side effects of Cabotegravir include injection site reactions, such as pain or redness. Most people take this medication without experiencing significant side effects, but it's important to report any new symptoms to your doctor.

  • Cabotegravir may cause liver problems, so regular liver function tests are recommended. It's not recommended for people with severe liver issues or during pregnancy unless necessary. Always consult your doctor about any concerns before starting Cabotegravir.

Indications and Purpose

How does Cabotegravir work?

Cabotegravir works by blocking an enzyme called integrase, which the HIV virus needs to multiply. Think of it like putting a lock on a door to stop unwanted guests. By preventing the virus from multiplying, Cabotegravir helps reduce the risk of HIV infection.

Is Cabotegravir effective?

Cabotegravir is effective for preventing HIV infection in people at high risk. Clinical studies show it significantly reduces the risk of HIV transmission when used as prescribed. It's important to follow your doctor's instructions and continue regular check-ups to ensure the medication is working effectively for you.

What is Cabotegravir?

Cabotegravir is a medication used for HIV prevention. It belongs to a class of drugs called integrase inhibitors, which block the virus from multiplying in your body. This helps reduce the risk of HIV infection. Cabotegravir is often used in combination with other medications for better protection.

Directions for Use

For how long do I take Cabotegravir?

Cabotegravir is usually a long-term medication for preventing HIV infection. You'll typically take it as prescribed by your doctor for as long as you need protection. How long you'll need this medication depends on your risk factors and overall health. Always talk with your doctor before changing or stopping your Cabotegravir treatment.

How do I dispose of Cabotegravir?

If you have unused Cabotegravir, bring it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly. If you can't find a take-back program, ask your pharmacist for advice on safe disposal methods.

How do I take Cabotegravir?

Cabotegravir is usually given as an injection by a healthcare professional. It's important to follow your doctor's instructions on when and how often to receive the injection. If you miss a dose, contact your healthcare provider for advice. There are no specific dietary or beverage restrictions while taking Cabotegravir, but always follow your doctor's specific advice about diet and fluid intake.

How long does it take for Cabotegravir to start working?

Cabotegravir begins working shortly after administration. However, it may take several days to achieve its full protective effect against HIV. The time it takes to work can depend on individual factors like your overall health. Follow your doctor's instructions for the best results.

How should I store Cabotegravir?

Store Cabotegravir at room temperature, away from moisture and light. Keep it in its original packaging until you're ready to use it. Don't store it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental ingestion.

What is the usual dose of Cabotegravir?

The usual dose of Cabotegravir for adults is an injection given by a healthcare professional. The frequency and amount depend on your specific treatment plan. Your doctor will determine the best dosing schedule for you. Always follow your doctor's specific dosing instructions for your personal health needs.

Warnings and Precautions

Can Cabotegravir be taken safely while breastfeeding?

Cabotegravir is not recommended while breastfeeding. There's limited information on whether it passes into human breast milk. If you're taking Cabotegravir and want to breastfeed, talk with your doctor about safer medication options that would allow you to nurse your baby safely.

Can Cabotegravir be taken safely while pregnant?

Cabotegravir isn't recommended during pregnancy unless the benefits outweigh the risks. There's limited information on its safety in pregnant women. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your health during this time.

Can I take Cabotegravir with other prescription drugs?

Cabotegravir may interact with other medications that affect liver enzymes. These interactions can increase the risk of side effects or reduce the effectiveness of Cabotegravir. Always inform your doctor about all medications you're taking to avoid potential interactions.

Does Cabotegravir have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Cabotegravir include injection site reactions, such as pain or redness. Serious side effects are rare but can include liver problems. If you notice any new or worsening symptoms, contact your doctor immediately. Your doctor can help determine if these symptoms are related to Cabotegravir.

Does Cabotegravir have any safety warnings?

Yes, Cabotegravir has important safety warnings. It may cause liver problems, so regular liver function tests are recommended. If you experience symptoms like yellowing of the skin or eyes, dark urine, or severe stomach pain, seek medical help immediately. Not adhering to these warnings can lead to serious health issues.

Is Cabotegravir addictive?

Cabotegravir is not addictive or habit-forming. This medication doesn't cause dependency or withdrawal symptoms when you stop taking it. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Cabotegravir doesn't carry this risk.

Is Cabotegravir safe for the elderly?

The elderly may be more vulnerable to side effects due to age-related changes in liver and kidney function. Cabotegravir is generally safe for the elderly, but they should be monitored closely for any adverse effects. Always consult a doctor for personalized advice.

Is it safe to drink alcohol while taking Cabotegravir?

It's best to avoid alcohol while taking Cabotegravir. Alcohol can affect your liver, and since Cabotegravir can also impact liver function, combining the two might increase the risk of liver problems. Talk with your doctor about alcohol use while taking Cabotegravir to get personalized advice.

Is it safe to exercise while taking Cabotegravir?

You can exercise while taking Cabotegravir. This medication doesn't typically limit exercise capacity. However, if you feel dizzy or lightheaded during exercise, slow down or stop and rest. Drink plenty of water before, during, and after physical activity to stay hydrated.

Is it safe to stop Cabotegravir?

Stopping Cabotegravir suddenly can affect your treatment. If you're taking it for HIV prevention, stopping could increase your risk of infection. Always talk with your doctor before stopping Cabotegravir. They might suggest a different medication or plan to keep your condition under control. Your doctor will help you make any medication changes safely.

What are the most common side effects of Cabotegravir?

Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Cabotegravir include injection site reactions like pain or redness. These effects vary from person to person. If you notice new symptoms after starting Cabotegravir, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking Cabotegravir?

Don't take Cabotegravir if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Cabotegravir is not recommended for people with severe liver problems. Always consult your doctor about any concerns or conditions you have before starting Cabotegravir.