Brivaracetam
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
None
Controlled Drug Substance
YES
brivaracetam
Summary
Brivaracetam is used to treat partial-onset seizures, which are seizures that start in one part of the brain, in people with epilepsy. It helps reduce the frequency of these seizures and is often used alongside other epilepsy treatments to improve the quality of life for those affected.
Brivaracetam works by affecting certain chemicals in the brain. It binds to a protein called synaptic vesicle protein 2A, which is involved in the release of neurotransmitters, helping to stabilize electrical activity in the brain and reduce seizure frequency.
The usual starting dose for adults is 50 mg taken twice daily, which means once in the morning and once in the evening. The maximum recommended dose is 200 mg per day. It can be taken with or without food, and the tablets should be swallowed whole.
Common side effects of Brivaracetam include dizziness, which is a feeling of being unsteady, drowsiness, which is feeling sleepy, and fatigue, which is extreme tiredness. These effects are usually mild but should be discussed with a doctor if they persist.
Brivaracetam may cause dizziness or drowsiness, affecting your ability to drive. It can increase the risk of suicidal thoughts, which are thoughts about harming oneself. People allergic to Brivaracetam or its ingredients should not use it. Always consult a doctor before starting or stopping the medication.
Indications and Purpose
How does Brivaracetam work?
Brivaracetam works by affecting certain chemicals in the brain to help control seizures. It binds to a protein called synaptic vesicle protein 2A, which is involved in the release of neurotransmitters. This action helps stabilize electrical activity in the brain, reducing the frequency of seizures. Think of it like a traffic light that helps regulate the flow of cars, ensuring a smooth and controlled movement.
Is Brivaracetam effective?
Brivaracetam is effective in treating partial-onset seizures in people with epilepsy. Clinical studies show it significantly reduces seizure frequency in patients. It works by affecting certain chemicals in the brain to help control seizures. This evidence supports its effectiveness for the indicated use. Always follow your doctor's instructions to achieve the best results.
What is Brivaracetam?
Brivaracetam is a medication used to treat partial-onset seizures in people with epilepsy. It belongs to the class of drugs called anticonvulsants, which help control seizures by affecting certain chemicals in the brain. Brivaracetam is used as a complementary addition to other therapies for epilepsy management. It helps reduce the frequency of seizures and improve the quality of life for those affected by epilepsy.
Directions for Use
For how long do I take Brivaracetam?
Brivaracetam is usually a long-term medication for managing epilepsy. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your condition to worsen. How long you'll need this medication depends on your body's response, any side effects you experience, and changes in your overall health. Always talk with your doctor before changing or stopping your Brivaracetam treatment.
How do I dispose of Brivaracetam?
To dispose of Brivaracetam, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. Mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Brivaracetam?
Brivaracetam is usually taken twice daily, once in the morning and once in the evening, with or without food. You should swallow the tablets whole and not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Always follow your doctor's specific instructions.
How long does it take for Brivaracetam to start working?
Brivaracetam begins working shortly after you take it, but it may take several weeks to achieve its full therapeutic effect. The time it takes to notice improvements can vary based on individual factors like age, overall health, and other medications you're taking. It's important to take Brivaracetam exactly as prescribed and attend regular check-ups with your doctor to monitor your progress.
How should I store Brivaracetam?
Store Brivaracetam at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, where moisture can affect its effectiveness. Always store Brivaracetam out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Brivaracetam?
The usual starting dose of Brivaracetam for adults is 50 mg twice daily. Your doctor may adjust your dose based on your response and needs. The maximum recommended dose is 200 mg per day. For children and the elderly, dose adjustments may be necessary. Always follow your doctor's specific dosing instructions for your personal health needs.
Warnings and Precautions
Can Brivaracetam be taken safely while breastfeeding?
The safety of Brivaracetam while breastfeeding is not well-established. It's unclear if the medication passes into human breast milk. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest options for managing your condition. Your doctor can help determine the best treatment plan for you and your baby.
Can Brivaracetam be taken safely while pregnant?
The safety of Brivaracetam during pregnancy is not well-established. Limited evidence makes it difficult to provide definitive advice. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.
Can I take Brivaracetam with other prescription drugs?
Brivaracetam can interact with other medications, such as carbamazepine and phenytoin, which may increase the risk of side effects or reduce effectiveness. It's important to inform your doctor about all the medications you're taking to avoid potential interactions. Your doctor can adjust your treatment plan to ensure safety and effectiveness.
Does Brivaracetam have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Brivaracetam include dizziness, drowsiness, and fatigue. These occur in a small percentage of users. Serious side effects can include mood changes or suicidal thoughts, which require immediate medical attention. Always inform your doctor about any new or worsening symptoms while taking Brivaracetam to ensure your safety and well-being.
Does Brivaracetam have any safety warnings?
Brivaracetam has important safety warnings. It may cause dizziness or drowsiness, affecting your ability to drive or operate machinery. It can also increase the risk of suicidal thoughts or behavior. If you experience mood changes, depression, or suicidal thoughts, contact your doctor immediately. Not adhering to these warnings can lead to serious consequences, so it's crucial to follow your doctor's advice and report any concerning symptoms.
Is Brivaracetam addictive?
Brivaracetam is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Brivaracetam works by affecting certain chemicals in the brain to help control seizures. This mechanism doesn't lead to addiction. If you have concerns about medication dependence, discuss them with your doctor to ensure your treatment plan is safe and effective.
Is Brivaracetam safe for the elderly?
Elderly individuals may be more vulnerable to the side effects of Brivaracetam, such as dizziness or drowsiness. These effects can increase the risk of falls or accidents. It's important for elderly patients to be closely monitored by their healthcare provider while taking Brivaracetam. Dose adjustments may be necessary to ensure safety and effectiveness.
Is it safe to drink alcohol while taking Brivaracetam?
It's best to avoid alcohol while taking Brivaracetam. Alcohol can increase the risk of side effects like dizziness and drowsiness, which may impair your ability to function safely. If you choose to drink occasionally, limit your alcohol intake and be aware of any warning signs like increased dizziness or drowsiness. Talk with your doctor about alcohol use while taking Brivaracetam for personalized advice.
Is it safe to exercise while taking Brivaracetam?
You can exercise while taking Brivaracetam, but be cautious. This medication can cause dizziness or drowsiness, which might affect your ability to exercise safely. If you feel dizzy or lightheaded during physical activity, slow down or stop and rest. Drink plenty of water and avoid strenuous activities until you know how Brivaracetam affects you. Consult your doctor if you have concerns about exercising while on this medication.
Is it safe to stop Brivaracetam?
Stopping Brivaracetam suddenly can cause serious problems, such as increased seizure frequency. It's important to talk with your doctor before stopping the medication. They might suggest gradually reducing your dose to prevent withdrawal symptoms and keep your condition under control. Your doctor will help you make any medication changes safely to protect your health.
What are the most common side effects of Brivaracetam?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Brivaracetam include dizziness, drowsiness, and fatigue. These effects vary from person to person. If you notice new symptoms after starting Brivaracetam, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Brivaracetam?
Brivaracetam should not be used by people allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Caution is needed for those with a history of depression or suicidal thoughts, as Brivaracetam can increase these risks. Always consult your doctor about any concerns or conditions before starting Brivaracetam to ensure it's safe for you.
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