Brexpiprazole
Major Depressive Disorder, Schizophrenia
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Atypical Antipsychotic
Controlled Drug Substance
No
brexpiprazole
Summary
Brexpiprazole is used to treat schizophrenia, which is a mental disorder causing hallucinations and delusions, and major depressive disorder, which is a condition marked by persistent sadness and loss of interest.
Brexpiprazole works by balancing chemicals in the brain, specifically dopamine and serotonin, which are involved in mood and behavior, helping to improve symptoms like mood swings and hallucinations.
The usual starting dose for adults is 1 mg once daily, with a maximum of 4 mg daily. It is taken orally, which means by mouth, and can be taken with or without food.
Common side effects include tiredness, dizziness, and weight gain, which means an increase in body weight. These effects are usually mild to moderate.
Brexpiprazole may increase the risk of suicidal thoughts, especially in young adults. It should not be used by those allergic to it or with severe allergic reactions to similar drugs.
Indications and Purpose
How does Brexpiprazole work?
Brexpiprazole works by affecting certain chemicals in the brain, specifically dopamine and serotonin, which are involved in mood and behavior. It helps balance these chemicals, reducing symptoms of schizophrenia and depression. Think of it like adjusting the volume on a radio to get a clearer sound. By fine-tuning these brain chemicals, Brexpiprazole helps improve mood, reduce hallucinations, and stabilize emotions.
Is Brexpiprazole effective?
Brexpiprazole is effective for treating conditions like schizophrenia and major depressive disorder. It works by balancing certain chemicals in the brain, which helps improve symptoms. Clinical studies show that Brexpiprazole can reduce symptoms of these conditions and improve overall functioning. Always follow your doctor's instructions and attend regular check-ups to monitor your progress and ensure the medication is working effectively for you.
What is Brexpiprazole?
Brexpiprazole is an antipsychotic medication used to treat schizophrenia and major depressive disorder. It works by balancing certain chemicals in the brain, which helps improve symptoms like mood swings, hallucinations, and depression. Brexpiprazole is often used in combination with other therapies to enhance its effectiveness. Always follow your doctor's instructions and attend regular check-ups to ensure the medication is working effectively for you.
Directions for Use
For how long do I take Brexpiprazole?
Brexpiprazole is usually taken long-term for chronic conditions like schizophrenia or depression. The duration depends on your response to treatment and any side effects you experience. Your doctor will guide you on how long to continue taking Brexpiprazole. Regular check-ups are important to assess your progress and make any necessary adjustments to your treatment plan. Always talk with your doctor before changing or stopping your medication.
How do I dispose of Brexpiprazole?
Dispose of Brexpiprazole by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options are unavailable, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away. This helps prevent harm to people and the environment.
How do I take Brexpiprazole?
Take Brexpiprazole exactly as your doctor prescribes. It's usually taken once daily, with or without food. Swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Avoid alcohol while taking Brexpiprazole, as it can increase side effects. Always follow your doctor's specific instructions regarding diet and fluid intake.
How long does it take for Brexpiprazole to start working?
Brexpiprazole may start working within a few days, but it can take several weeks to achieve its full therapeutic effect. Individual factors like age, overall health, and the specific condition being treated can affect how quickly you notice improvements. Regular check-ups with your doctor are important to monitor your progress and make any necessary adjustments to your treatment plan. Always take Brexpiprazole as prescribed for the best results.
How should I store Brexpiprazole?
Store Brexpiprazole at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, as moisture can affect its effectiveness. Always keep Brexpiprazole out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Brexpiprazole?
The usual starting dose of Brexpiprazole for adults is 1 mg once daily. Your doctor may adjust the dose based on your response and needs, with a maximum recommended dose of 4 mg daily. Dose adjustments may be necessary for special populations, such as the elderly or those with liver or kidney issues. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can Brexpiprazole be taken safely while breastfeeding?
Brexpiprazole is not recommended while breastfeeding. Limited information is available on whether it passes into human breast milk. Animal studies suggest it may appear in milk and affect the nursing infant. If you're breastfeeding or planning to breastfeed, talk with your doctor about safer medication options. They can help you choose a treatment that allows you to nurse your baby safely.
Can Brexpiprazole be taken safely while pregnant?
Brexpiprazole is not recommended during pregnancy unless the benefits outweigh the risks. Limited information is available on its safety in pregnant women. Animal studies suggest potential risks to the developing fetus. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options for your condition. They can help create a plan that protects both you and your baby.
Can I take Brexpiprazole with other prescription drugs?
Brexpiprazole can interact with other medications, increasing the risk of side effects or reducing effectiveness. Major interactions include drugs that affect the central nervous system, like sedatives or antidepressants, which can increase drowsiness. Moderate interactions include medications that affect liver enzymes, which can alter Brexpiprazole levels in your body. Always inform your doctor about all medications you take to avoid potential interactions and ensure safe use of Brexpiprazole.
Does Brexpiprazole have adverse effects?
Adverse effects are unwanted reactions to a medication. Brexpiprazole can cause side effects like weight gain, restlessness, and dizziness. These effects vary in frequency and severity. Serious adverse effects include increased risk of suicidal thoughts, especially in young adults. If you notice any new or worsening symptoms, contact your doctor immediately. They can help determine if these are related to Brexpiprazole and adjust your treatment if necessary.
Does Brexpiprazole have any safety warnings?
Yes, Brexpiprazole has important safety warnings. It may increase the risk of suicidal thoughts and behaviors, especially in young adults. It can also cause metabolic changes like weight gain and high blood sugar. Not following these warnings can lead to serious health issues. Always discuss any concerns with your doctor and follow their guidance closely to ensure safe use of Brexpiprazole.
Is Brexpiprazole addictive?
Brexpiprazole is not considered addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Brexpiprazole works by affecting certain chemicals in the brain to help manage symptoms of mental health conditions. This mechanism does not lead to addiction. If you have concerns about medication dependence, discuss them with your doctor for reassurance and guidance.
Is Brexpiprazole safe for the elderly?
Brexpiprazole can be used by the elderly, but they may be more vulnerable to side effects like dizziness, which can increase the risk of falls. The elderly may also experience more pronounced effects on blood pressure and metabolism. Doctors often start with a lower dose and monitor closely. Regular check-ups are important to ensure the medication is safe and effective for older adults.
Is it safe to drink alcohol while taking Brexpiprazole?
It's best to avoid alcohol while taking Brexpiprazole. Alcohol can increase the risk of side effects like dizziness, drowsiness, and impaired judgment. These effects can be dangerous, especially if you need to drive or operate machinery. If you choose to drink occasionally, limit your alcohol intake and be aware of how your body responds. Talk with your doctor about alcohol use while taking Brexpiprazole for personalized advice.
Is it safe to exercise while taking Brexpiprazole?
You can exercise while taking Brexpiprazole, but be cautious. This medication can cause dizziness or drowsiness, which might affect your ability to exercise safely. Start with light activities and gradually increase intensity as you see how your body responds. Stay hydrated and avoid strenuous activities if you feel unwell. If you have concerns about exercising while on Brexpiprazole, talk with your doctor for guidance.
Is it safe to stop Brexpiprazole?
It's not safe to stop Brexpiprazole suddenly without consulting your doctor. Stopping abruptly can worsen your condition or cause withdrawal symptoms like nausea, dizziness, or agitation. Your doctor may suggest gradually reducing the dose to minimize risks. Always talk with your doctor before making any changes to your medication to ensure your health is protected.
What are the most common side effects of Brexpiprazole?
Side effects are unwanted reactions to a medication. Common side effects of Brexpiprazole include weight gain, dizziness, and restlessness. These occur in more than 10% of users. If you experience new symptoms after starting Brexpiprazole, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication to ensure your treatment remains safe and effective.
Who should avoid taking Brexpiprazole?
Brexpiprazole should not be used if you are allergic to it or its ingredients. It is not recommended for people with a history of severe allergic reactions to similar medications. Caution is needed for those with a history of seizures, heart problems, or diabetes. Always discuss your medical history with your doctor to ensure Brexpiprazole is safe for you.
