Bisoprolol + Telmisartan
Find more information about this combination medication at the webpages for Bisoprolol and Telmisartan
Hypertension, Supraventricular Tachycardia ... show more
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Advisory
- This medicine contains a combination of 2 drugs Bisoprolol and Telmisartan.
- Bisoprolol and Telmisartan are both used to treat the same disease or symptom but work in different ways in the body.
- Most doctors will advise making sure that each individual medicine is safe and effective before using a combination form.
Drug Status
Government Approvals
None
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Angiotensin 2 Receptor Blocker and Beta-Adrenergic Blocker
Controlled Drug Substance
NO
Bisoprolol + Telmisartan
Summary
Bisoprolol is primarily used to treat high blood pressure, which is a condition where the force of the blood against the artery walls is too high, and heart failure, which is when the heart is unable to pump blood effectively. Telmisartan is also used to treat high blood pressure and is additionally used to reduce the risk of cardiovascular events, which are incidents like heart attacks and strokes, in patients who are at high risk. Both medications help manage hypertension, which is another term for high blood pressure, to prevent serious health issues.
Bisoprolol works by blocking beta-adrenergic receptors, which are parts of the heart that respond to adrenaline, slowing the heart rate and reducing the force of heart contractions. This helps lower blood pressure. Telmisartan blocks the action of angiotensin II, which is a substance that causes blood vessels to tighten. By blocking this action, Telmisartan relaxes the blood vessels, allowing blood to flow more easily and reducing blood pressure. Both medications aim to lower blood pressure and reduce the risk of cardiovascular events, but they do so through different mechanisms.
Bisoprolol is usually started at a dose of 5 mg once daily, which can be adjusted based on how the patient responds and tolerates the medication, with a maximum dose of 20 mg per day. Telmisartan typically starts at 40 mg once daily, which can be increased to 80 mg if needed. Both medications are taken orally, meaning they are swallowed, and are often prescribed to be taken once a day, ideally at the same time each day to maintain consistent blood levels and effectiveness.
Common side effects of Bisoprolol include headache, dizziness, tiredness, and nausea. Telmisartan may cause back pain, sinus pain, and diarrhea. Both medications can cause dizziness and fatigue, which are common to many blood pressure-lowering drugs. Serious adverse effects, though rare, can include severe allergic reactions, significant drops in blood pressure, and heart problems. Patients should report any severe or persistent side effects to their healthcare provider.
Bisoprolol is contraindicated, meaning it should not be used, in patients with severe heart failure, bradycardia, which is a slow heart rate, or certain heart blockages. Telmisartan should not be used during pregnancy due to the risk of fetal harm. Both medications require caution in patients with kidney or liver impairment. Patients should be aware of the risk of dizziness and hypotension, which is low blood pressure, especially when starting treatment or adjusting doses. It's crucial to follow healthcare provider instructions and report any unusual symptoms immediately.
Indications and Purpose
How does combination of Bisoprolol and Telmisartan work?
Bisoprolol works by blocking beta-adrenergic receptors in the heart, which slows down the heart rate and reduces the force of heart contractions, leading to lower blood pressure. Telmisartan blocks the action of angiotensin II, a substance that causes blood vessels to tighten, thereby relaxing the blood vessels and allowing blood to flow more easily. Both medications ultimately aim to lower blood pressure and reduce the risk of cardiovascular events, but they do so through different mechanisms.
How does combination of Telmisartan and Bisoprolol work?
Telmisartan works by blocking the action of angiotensin II, a chemical in the body that causes blood vessels to constrict, thereby lowering blood pressure and reducing the risk of cardiovascular events. Bisoprolol, on the other hand, is a beta-blocker that reduces the heart rate and the heart's workload by blocking the effects of adrenaline on the heart. Both medications help in managing high blood pressure, but they do so through different mechanisms. Together, they provide a comprehensive approach to cardiovascular health by addressing both vascular resistance and cardiac output.
How effective is combination of Bisoprolol and Telmisartan?
Clinical trials and studies have demonstrated the effectiveness of both Bisoprolol and Telmisartan in lowering blood pressure and reducing the risk of cardiovascular events. Bisoprolol has been shown to improve heart function and reduce symptoms in heart failure patients. Telmisartan has been proven to lower blood pressure and reduce the risk of heart attacks and strokes in high-risk patients. Both medications have been widely studied and are considered effective treatments for hypertension, with benefits observed in various patient populations.
How effective is combination of Telmisartan and Bisoprolol?
Telmisartan's effectiveness is supported by clinical trials demonstrating its ability to lower blood pressure and reduce the risk of cardiovascular events in high-risk patients. Studies like ONTARGET and TRANSCEND have shown its benefits in reducing myocardial infarction and stroke. Bisoprolol's efficacy is well-documented in managing hypertension and heart failure, with evidence showing its ability to improve heart function and reduce mortality in heart failure patients. Both medications have been proven effective in lowering blood pressure, though they work through different mechanisms. Their combined use can provide a more comprehensive cardiovascular risk management strategy.
Directions for Use
What is the usual dose of combination of Bisoprolol and Telmisartan?
The usual adult daily dose for Bisoprolol typically starts at 5 mg once daily, which can be adjusted based on the patient's response and tolerance, with a maximum dose of 20 mg per day. For Telmisartan, the starting dose is usually 40 mg once daily, which can be increased to 80 mg if needed. Both medications are taken orally and are often prescribed to be taken once a day, ideally at the same time each day to maintain consistent blood levels and effectiveness.
What is the usual dose of combination of Telmisartan and Bisoprolol?
The usual starting dose for Telmisartan in adults is 40 mg once daily, which can be adjusted based on the patient's response, with a typical range of 20 to 80 mg per day. For Bisoprolol, the usual starting dose is 5 mg once daily, which can be increased to a maximum of 20 mg per day depending on the patient's needs and tolerance. Both medications are taken orally and can be adjusted based on individual patient response and specific health conditions. They are often used in combination to manage hypertension more effectively.
How does one take combination of Bisoprolol and Telmisartan?
Bisoprolol can be taken with or without food, but it should be taken at the same time each day to maintain consistent blood levels. Telmisartan can also be taken with or without food, and it is important to take it at the same time daily. Patients are advised to follow any specific dietary instructions provided by their healthcare provider, such as maintaining a low-salt diet, which can enhance the effectiveness of these medications in controlling blood pressure.
How does one take combination of Telmisartan and Bisoprolol?
Telmisartan can be taken with or without food, and there are no specific food restrictions associated with its use. Bisoprolol should also be taken consistently, either with or without food, to maintain stable blood levels. Patients are advised to take both medications at the same time each day to help remember their doses. While there are no strict dietary restrictions, patients should avoid excessive consumption of potassium-rich foods or supplements when taking Telmisartan, as it can increase potassium levels in the blood. It's important to follow the healthcare provider's instructions and report any unusual symptoms.
For how long is combination of Bisoprolol and Telmisartan taken?
Both Bisoprolol and Telmisartan are typically used as long-term treatments for managing high blood pressure. They are not cures but are intended to control blood pressure over time, which means they are usually taken indefinitely unless a healthcare provider advises otherwise. Regular monitoring by a healthcare professional is essential to ensure the medications are effectively managing blood pressure and to adjust dosages if necessary.
For how long is combination of Telmisartan and Bisoprolol taken?
Telmisartan and Bisoprolol are typically used as long-term treatments for managing high blood pressure and associated cardiovascular risks. The duration of use is generally indefinite, as these medications are intended to control chronic conditions rather than cure them. Patients are advised to continue taking these medications as prescribed by their healthcare provider, even if they feel well, to maintain blood pressure control and reduce the risk of cardiovascular events. Regular monitoring and follow-up with a healthcare provider are essential to assess the effectiveness and adjust dosages if necessary.
How long does it take for combination of Bisoprolol and Telmisartan to work?
Bisoprolol and Telmisartan both work to lower blood pressure, but they have different onset times. Bisoprolol, a beta-blocker, may take a few weeks to show its full effect on blood pressure, although some improvement might be noticed earlier. Telmisartan, an angiotensin II receptor antagonist, can start to lower blood pressure within the first two weeks, with full effects typically seen after four weeks. Both medications require consistent daily intake to maintain their blood pressure-lowering effects.
How long does it take for combination of Telmisartan and Bisoprolol to work?
Telmisartan typically starts to show its antihypertensive effects within 3 hours after administration, with maximal reduction in blood pressure generally achieved after about 4 weeks of consistent use. Bisoprolol, on the other hand, begins to work within 1 to 2 hours after ingestion, with its peak effects occurring within 2 to 4 hours. Both medications are used to manage high blood pressure, but they work through different mechanisms. Telmisartan is an angiotensin II receptor blocker, while Bisoprolol is a beta-blocker. Together, they can provide a comprehensive approach to lowering blood pressure, though the onset of action may vary slightly between the two.
Warnings and Precautions
Are there harms and risks from taking combination of Bisoprolol and Telmisartan?
Common side effects of Bisoprolol include headache, dizziness, tiredness, and nausea. Telmisartan may cause back pain, sinus pain, and diarrhea. Both medications can cause dizziness and fatigue, which are common to many blood pressure-lowering drugs. Serious adverse effects, though rare, can include severe allergic reactions, significant drops in blood pressure, and heart problems. Patients should report any severe or persistent side effects to their healthcare provider.
Are there harms and risks from taking combination of Telmisartan and Bisoprolol?
Common side effects of Telmisartan include upper respiratory tract infections, back pain, sinusitis, and diarrhea. Significant adverse effects can include hypotension, hyperkalemia, and renal impairment. Bisoprolol may cause fatigue, dizziness, and cold extremities, with significant adverse effects including bradycardia and worsening heart failure. Both medications can cause dizziness and fatigue, and patients should be monitored for changes in blood pressure and heart rate. It's important to report any severe or persistent side effects to a healthcare provider.
Can I take combination of Bisoprolol and Telmisartan with other prescription drugs?
Bisoprolol can interact with other heart medications, such as calcium channel blockers, which may enhance its effects on heart rate and blood pressure. Telmisartan should not be used with aliskiren in patients with diabetes due to increased risk of kidney problems. Both medications can interact with NSAIDs, which may reduce their blood pressure-lowering effects. Patients should inform their healthcare provider of all medications they are taking to avoid potential interactions.
Can I take combination of Telmisartan and Bisoprolol with other prescription drugs?
Telmisartan should not be used with aliskiren in patients with diabetes due to the risk of renal impairment, hypotension, and hyperkalemia. It can also interact with digoxin, increasing its levels in the blood. Bisoprolol may interact with other beta-blockers, calcium channel blockers, and antiarrhythmic drugs, potentially leading to excessive heart rate reduction or heart block. Both medications require careful monitoring when used with other antihypertensive drugs to avoid excessive lowering of blood pressure. Patients should inform their healthcare provider of all medications they are taking to manage potential interactions effectively.
Can I take combination of Bisoprolol and Telmisartan if I am pregnant?
Bisoprolol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as it may affect fetal growth. Telmisartan is contraindicated during pregnancy, especially in the second and third trimesters, due to the risk of fetal harm, including kidney damage and death. Women of childbearing age should use effective contraception while taking these medications and consult their healthcare provider if they become pregnant.
Can I take combination of Telmisartan and Bisoprolol if I am pregnant?
Telmisartan is contraindicated during pregnancy due to the risk of fetal toxicity, including potential harm to the developing kidneys and increased risk of fetal and neonatal morbidity and death. It should be discontinued as soon as pregnancy is detected. Bisoprolol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as it may cause fetal growth retardation and neonatal hypoglycemia or bradycardia. Both medications require careful consideration and consultation with a healthcare provider to evaluate the risks and benefits if pregnancy occurs or is planned.
Can I take combination of Bisoprolol and Telmisartan while breastfeeding?
There is limited information on the safety of Bisoprolol and Telmisartan during lactation. Bisoprolol is known to pass into breast milk in small amounts, and caution is advised when administering to breastfeeding mothers. Telmisartan's effects on breastfed infants are not well-studied, and it is generally recommended to avoid its use during breastfeeding. Mothers should discuss potential risks and benefits with their healthcare provider to determine the best course of action.
Can I take combination of Telmisartan and Bisoprolol while breastfeeding?
There is limited information on the safety of Telmisartan during lactation, and it is advised that nursing mothers do not breastfeed while taking this medication due to potential adverse effects on the infant, such as hypotension and renal impairment. Bisoprolol is excreted in breast milk, and while it is generally considered safe, caution is advised, and infants should be monitored for signs of beta-blockade, such as bradycardia. Both medications require careful consideration of the benefits and risks, and alternative treatments should be discussed with a healthcare provider if breastfeeding is planned or ongoing.
Who should avoid taking combination of Bisoprolol and Telmisartan?
Bisoprolol is contraindicated in patients with severe heart failure, bradycardia, or certain heart blockages. Telmisartan should not be used during pregnancy due to the risk of fetal harm. Both medications require caution in patients with kidney or liver impairment. Patients should be aware of the risk of dizziness and hypotension, especially when starting treatment or adjusting doses. It's crucial to follow healthcare provider instructions and report any unusual symptoms immediately.
Who should avoid taking combination of Telmisartan and Bisoprolol?
Telmisartan carries a warning for fetal toxicity and should be discontinued as soon as pregnancy is detected. It is contraindicated in patients with known hypersensitivity to the drug and should not be used with aliskiren in patients with diabetes. Bisoprolol is contraindicated in patients with severe bradycardia, heart block, or cardiogenic shock. Both medications require caution in patients with renal or hepatic impairment. Patients should be aware of the risk of hypotension and should report any symptoms of dizziness or fainting to their healthcare provider. Regular monitoring and communication with a healthcare provider are essential to manage these risks.
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