Betahistine
Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Histamine-1 Receptor Antagonist
Controlled Drug Substance
NO

Betahistine
Summary
Betahistine is used to treat vertigo, which is a sensation of spinning or dizziness, and Meniere's disease, which is a disorder of the inner ear causing vertigo, tinnitus, and hearing loss.
Betahistine works by improving blood flow in the inner ear, which helps reduce symptoms of vertigo by balancing pressure and improving balance.
The usual starting dose for adults is 8 to 16 mg taken three times a day. It should be taken with food to reduce stomach upset. The maximum recommended dose is 48 mg per day.
Common side effects include nausea and headache, which are usually mild. If these symptoms persist, consult your doctor.
Betahistine should not be used by people with pheochromocytoma, which is a rare tumor of the adrenal gland. Caution is needed for those with asthma or a history of peptic ulcers.
Indications and Purpose
How does Betahistine work?
Betahistine works by improving blood flow in the inner ear, which helps reduce symptoms of vertigo. It acts as a histamine analog, which means it mimics the action of histamine, a natural substance in the body. This action helps to balance the pressure in the inner ear, reducing dizziness and improving balance. Think of it like adjusting the volume on a radio to reduce static and improve sound clarity. Betahistine is effective for managing vertigo and Meniere's disease.
Is Betahistine effective?
Betahistine is effective for treating vertigo, which is a sensation of spinning or dizziness. It works by improving blood flow in the inner ear, which helps reduce symptoms. Clinical studies support its effectiveness in managing vertigo symptoms. Most people experience relief from dizziness and improved balance while taking Betahistine. If you have concerns about its effectiveness, discuss them with your doctor. They can help determine if Betahistine is the right treatment for you.
What is Betahistine?
Betahistine is a medication used to treat vertigo, which is a sensation of spinning or dizziness. It belongs to a class of drugs called histamine analogs. Betahistine works by improving blood flow in the inner ear, which helps reduce symptoms of vertigo. It's also used to manage Meniere's disease, which is a disorder of the inner ear causing vertigo, tinnitus, and hearing loss. Betahistine is usually taken as a complementary addition to other therapies.
Directions for Use
For how long do I take Betahistine?
Betahistine is usually taken long-term for managing conditions like vertigo. The duration of use depends on your response and the severity of your symptoms. Your doctor will guide you on how long to continue taking Betahistine. It's important to follow their advice and not stop the medication without consulting them. They can help determine the best treatment plan for your needs.
How do I dispose of Betahistine?
To dispose of Betahistine, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal the mixture in a plastic bag, and throw it away.
How do I take Betahistine?
Take Betahistine as prescribed by your doctor, usually 8 to 16 mg three times a day. It's best to take it with food to reduce stomach upset. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses. Always follow your doctor's specific instructions regarding your dosage and any dietary restrictions.
How long does it take for Betahistine to start working?
Betahistine may start working within a few days, but it can take several weeks to achieve its full therapeutic effect. The time it takes to work can vary depending on individual factors like the severity of your condition and your overall health. It's important to take Betahistine as prescribed and be patient while waiting for the full benefits. If you have concerns about how long it's taking to work, talk with your doctor.
How should I store Betahistine?
Store Betahistine at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Avoid storing it in humid places like bathrooms, as moisture can affect its effectiveness. Always keep Betahistine out of children's reach to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Betahistine?
The usual starting dose of Betahistine for adults is 8 to 16 mg taken three times a day. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 48 mg per day. Betahistine is not typically used in children, and elderly patients may require careful monitoring. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can Betahistine be taken safely while breastfeeding?
The safety of Betahistine while breastfeeding is not well-established. It's unclear if Betahistine passes into breast milk or affects milk supply. If you're breastfeeding or planning to breastfeed, talk with your doctor about the safest treatment options. They can help determine if Betahistine is appropriate for you and your baby. Always consult your healthcare provider before starting or continuing Betahistine while breastfeeding.
Can Betahistine be taken safely while pregnant?
The safety of Betahistine during pregnancy is not well-established. Limited evidence makes it difficult to provide definitive advice. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest treatment options. They can help create a plan that protects both you and your baby. Always consult your healthcare provider before starting or continuing Betahistine during pregnancy.
Can I take Betahistine with other prescription drugs?
Betahistine may interact with antihistamines, which can reduce its effectiveness. It can also interact with medications that affect blood pressure, potentially increasing side effects. Always inform your doctor about all the medications you're taking to avoid interactions. They can help adjust your treatment plan to ensure it's safe and effective. If you have concerns about specific drug interactions, discuss them with your healthcare provider.
Does Betahistine have adverse effects?
Adverse effects are unwanted reactions to a medication. With Betahistine, common adverse effects include nausea and headache. These occur occasionally and are usually mild. Serious side effects are rare but can include allergic reactions, which require immediate medical attention. If you notice any new or worsening symptoms while taking Betahistine, contact your doctor. They can help determine if these symptoms are related to the medication and suggest appropriate actions.
Does Betahistine have any safety warnings?
Betahistine has some safety warnings. It should be used cautiously in people with asthma or a history of peptic ulcers, which are sores in the stomach lining. Not adhering to these warnings can worsen these conditions. If you experience symptoms like difficulty breathing or stomach pain, contact your doctor immediately. Always inform your healthcare provider about your medical history before starting Betahistine to ensure it's safe for you.
Is Betahistine addictive?
Betahistine is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Betahistine works by improving blood flow in the inner ear, which doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, you can feel confident that Betahistine doesn't carry this risk.
Is Betahistine safe for the elderly?
Elderly individuals may be more vulnerable to the side effects of Betahistine, such as dizziness or stomach upset. These side effects can increase the risk of falls or other complications. Betahistine is generally safe for the elderly when used as directed, but careful monitoring is important. If you're an older adult taking Betahistine, talk with your doctor about any concerns. They can help ensure the medication is safe and effective for you.
Is it safe to drink alcohol while taking Betahistine?
It's best to avoid alcohol while taking Betahistine. Alcohol can increase the risk of side effects like dizziness and stomach upset. These symptoms can interfere with the effectiveness of Betahistine. If you choose to drink occasionally, limit your alcohol intake and watch for any adverse effects. Talk with your doctor about alcohol use while taking Betahistine to get personalized advice based on your specific health situation.
Is it safe to exercise while taking Betahistine?
You can exercise while taking Betahistine, but be cautious. Betahistine can cause dizziness, which might affect your balance during physical activity. Start with light exercises and gradually increase intensity as you see how your body responds. If you feel dizzy or lightheaded, stop exercising and rest. Drink plenty of water to stay hydrated. Talk with your doctor if you have concerns about exercising while taking Betahistine.
Is it safe to stop Betahistine?
Betahistine is often used for long-term management of conditions like vertigo. Stopping it suddenly might cause symptoms to return. It's important to talk with your doctor before stopping Betahistine. They can guide you on how to safely discontinue the medication if needed. Your doctor might suggest gradually reducing your dose to prevent a return of symptoms. Always follow your doctor's advice to protect your health.
What are the most common side effects of Betahistine?
Side effects are unwanted reactions to a medication. Common side effects of Betahistine include nausea and headache. These occur occasionally and are usually mild. If you experience these side effects, they might be temporary or unrelated to the medication. Talk with your doctor if you have concerns or if the side effects persist. They can help determine if the symptoms are related to Betahistine and suggest ways to manage them.
Who should avoid taking Betahistine?
Betahistine should not be used by people with pheochromocytoma, which is a rare tumor of the adrenal gland, due to severe risks. Caution is needed for those with asthma or a history of peptic ulcers, which are sores in the stomach lining. In these cases, Betahistine may be used only if the benefits outweigh the risks. Always consult your doctor about your medical history before starting Betahistine.