Benazepril
Hypertension, Left Ventricular Dysfunction ... show more
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
Definite
Pharmaceutical Class
Angiotensin Converting Enzyme Inhibitor
Controlled Drug Substance
NO
Benazepril
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Click HereSummary
Benazepril is primarily used to treat high blood pressure, also known as hypertension. By lowering blood pressure, it reduces the risk of cardiovascular events like strokes and heart attacks.
Benazepril is an ACE inhibitor. It works by decreasing certain chemicals that tighten blood vessels, allowing blood to flow more smoothly. This helps lower blood pressure and reduces the workload on the heart.
For adults, the usual starting dose of Benazepril is 10 mg once daily, with a maintenance dose ranging from 20 to 40 mg per day. For children, the starting dose is 0.2 mg/kg once per day. The medication is taken orally, usually once or twice a day, with or without food.
Common side effects of Benazepril include cough, headache, dizziness, and drowsiness. Serious adverse effects include difficulty breathing, severe hypotension, and angioedema, which is swelling beneath the skin.
Benazepril should not be used during pregnancy as it can harm the fetus. It's also contraindicated in patients with a history of angioedema related to previous ACE inhibitor treatment. Patients with diabetes should not take it with aliskiren, a medication used to treat high blood pressure.
Indications and Purpose
What is Benazepril used for?
Benazepril is primarily indicated for the treatment of hypertension (high blood pressure). Lowering blood pressure helps reduce the risk of strokes, heart attacks, and kidney problems.
How does Benazepril work?
Benazepril inhibits the angiotensin-converting enzyme (ACE), reducing the production of angiotensin II, a substance that narrows blood vessels. This leads to relaxed blood vessels, lower blood pressure, and decreased workload on the heart.
Is Benazepril effective?
Benazepril is effective in lowering blood pressure, reducing the risk of cardiovascular events like strokes and heart attacks. Its effectiveness has been demonstrated in controlled trials of antihypertensive drugs.
How does one know if Benazepril is working?
The benefit of Benazepril is evaluated by regularly checking blood pressure to determine the response to the medication. Your doctor may also order lab tests to monitor your body's response.
Directions for Use
What is the usual dose of Benazepril?
For adults not on a diuretic, the initial dose is typically 10 mg once daily, with a maintenance range of 20 to 40 mg per day. For children, the starting dose is 0.2 mg/kg once daily, titrated as needed up to 0.6 mg/kg. Doses above 0.6 mg/kg or 40 mg daily have not been studied in children.
How do I take Benazepril?
Benazepril can be taken with or without food, usually once or twice a day. It's important to take it at the same time each day. Avoid using salt substitutes containing potassium unless advised by your doctor.
For how long do I take Benazepril?
Benazepril is used for long-term management of high blood pressure. It controls blood pressure but does not cure it, so it is typically taken indefinitely unless advised otherwise by a doctor.
How long does it take for Benazepril to start working?
Benazepril starts to lower blood pressure within 1 hour, with peak effects occurring between 2 to 4 hours after dosing. However, it may take several weeks to see the full benefits.
How should I store Benazepril?
Store Benazepril in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children and do not store it in the bathroom.
Warnings and Precautions
Who should avoid taking Benazepril?
Benazepril should not be used during pregnancy as it can harm the fetus. It is contraindicated in patients with a history of angioedema or those taking neprilysin inhibitors. Patients with diabetes should avoid using it with aliskiren.
Can I take Benazepril with other prescription drugs?
Benazepril can interact with diuretics, NSAIDs, and potassium supplements, potentially causing hypotension or hyperkalemia. It should not be used with neprilysin inhibitors or aliskiren in patients with diabetes.
Can I take Benazepril with vitamins or supplements?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Benazepril be taken safely while pregnant?
Benazepril is not recommended during pregnancy as it can harm the fetus, causing issues like renal failure and death. If pregnancy is detected, discontinue use immediately and consult a doctor.
Can Benazepril be taken safely while breastfeeding?
Minimal amounts of Benazepril are excreted in breast milk. While the risk to a newborn is low, consult your doctor to weigh the benefits and risks of continuing the medication while breastfeeding.
Is Benazepril safe for the elderly?
Elderly patients may have decreased renal function, so dose selection should be cautious, and renal function should be monitored. No overall differences in effectiveness or safety have been observed between elderly and younger patients.
Is it safe to exercise while taking Benazepril?
Benazepril does not specifically limit the ability to exercise. However, it can cause dizziness or lightheadedness, which might affect physical activity. If you experience these symptoms, consult your doctor before continuing with exercise.
Is it safe to drink alcohol while taking Benazepril?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
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