Atomoxetine

Attention Deficit Disorder with Hyperactivity

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

No

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Pharmaceutical Class

Norepinephrine Reuptake Inhibitor

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Controlled Drug Substance

No

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Drug Ingredient

atomoxetine

Summary

  • Atomoxetine is used to treat ADHD, which is attention deficit hyperactivity disorder. It helps improve focus, attention, and impulse control. ADHD is a condition where individuals have difficulty maintaining attention and controlling impulsive behaviors.

  • Atomoxetine works by affecting norepinephrine, which is a chemical in the brain involved in attention and impulse control. By increasing norepinephrine levels, it helps improve focus and reduce impulsivity in people with ADHD.

  • The usual starting dose for adults is 40 mg per day, which can be taken as a single dose or divided into two doses. The maximum recommended dose is 100 mg per day. It is taken orally, with or without food.

  • Common side effects include dry mouth, loss of appetite, and trouble sleeping. Some people may also experience tiredness or stomach upset. These effects vary from person to person and are usually mild.

  • Atomoxetine can increase the risk of suicidal thoughts in children and adolescents. It may cause liver damage, so watch for symptoms like yellowing of the skin. It should not be used with MAOIs, which are monoamine oxidase inhibitors, or in people with narrow-angle glaucoma.

Indications and Purpose

How does Atomoxetine work?

Atomoxetine works by affecting certain chemicals in the brain called neurotransmitters. It specifically targets norepinephrine, which is involved in attention and impulse control. By increasing norepinephrine levels, Atomoxetine helps improve focus and reduce impulsivity in people with ADHD, which is attention deficit hyperactivity disorder. Think of it like adjusting the volume on a radio to get a clearer signal. This helps the brain function more effectively.

Is Atomoxetine effective?

Atomoxetine is effective for treating ADHD, which is attention deficit hyperactivity disorder. It works by affecting certain chemicals in the brain to improve focus and reduce impulsivity. Clinical studies show that Atomoxetine significantly improves symptoms in many people with ADHD. It's important to follow your doctor's instructions and attend regular check-ups to monitor the medication's effectiveness and make any necessary adjustments.

What is Atomoxetine?

Atomoxetine is a medication used to treat ADHD, which is attention deficit hyperactivity disorder. It belongs to a class of drugs called selective norepinephrine reuptake inhibitors. Atomoxetine works by affecting certain chemicals in the brain to improve focus and reduce impulsivity. It's used primarily for ADHD but may also be prescribed for other conditions as determined by your doctor. Always follow your doctor's instructions when taking Atomoxetine.

Directions for Use

For how long do I take Atomoxetine?

Atomoxetine is usually taken long-term for managing ADHD, which is attention deficit hyperactivity disorder. The duration of use depends on your response to the medication and your overall health needs. Your doctor will guide you on how long to continue taking Atomoxetine. Regular check-ups are important to assess the effectiveness and make any necessary adjustments. Always follow your doctor's advice and discuss any concerns about the duration of treatment.

How do I dispose of Atomoxetine?

Dispose of Atomoxetine by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options aren't available, you can throw it in the trash at home. First, remove it from its original container, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. This helps prevent accidental ingestion or harm to the environment.

How do I take Atomoxetine?

Take Atomoxetine as prescribed by your doctor. It's usually taken once or twice daily, either in the morning or evening. You can take it with or without food. Swallow the capsule whole; do not crush or open it. If you miss a dose, take it as soon as you remember unless it's close to your next dose. In that case, skip the missed dose and continue your regular schedule. Avoid taking two doses at once. Always follow your doctor's specific instructions for the best results.

How long does it take for Atomoxetine to start working?

Atomoxetine may take several weeks to show its full effects. Some people notice improvements in focus and behavior within a few days, but it can take up to 6 weeks for the medication to reach its full therapeutic effect. Individual factors like age, weight, and overall health can affect how quickly Atomoxetine works. Be patient and continue taking the medication as prescribed. Regular check-ups with your doctor will help monitor progress.

How should I store Atomoxetine?

Store Atomoxetine at room temperature, away from moisture and light. Keep it in its original container with the lid tightly closed. Avoid storing it in humid places like bathrooms, as moisture can affect the medication's effectiveness. Always keep Atomoxetine out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.

What is the usual dose of Atomoxetine?

The usual starting dose of Atomoxetine for adults is 40 mg per day, which can be taken as a single dose or divided into two doses. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 100 mg per day. For children and the elderly, dose adjustments may be necessary. Always follow your doctor's specific dosing instructions for your health needs.

Warnings and Precautions

Can Atomoxetine be taken safely while breastfeeding?

The safety of Atomoxetine while breastfeeding is not well-established. It's unclear if the medication passes into breast milk and what effects it might have on a nursing infant. If you're breastfeeding or planning to breastfeed, discuss the risks and benefits with your doctor. They can help determine the best treatment plan for you and your baby, considering your health needs and the safety of your child.

Can Atomoxetine be taken safely while pregnant?

The safety of Atomoxetine during pregnancy is not well-established. Limited data is available, and the effects on the unborn baby are not fully known. If you're pregnant or planning to become pregnant, talk with your doctor about the risks and benefits of using Atomoxetine. They can help create a treatment plan that considers your health needs and the safety of your baby.

Can I take Atomoxetine with other prescription drugs?

Atomoxetine can interact with certain medications, increasing the risk of side effects. For example, it may interact with MAOIs, which are monoamine oxidase inhibitors, leading to serious reactions. It can also affect blood pressure medications. Always inform your doctor about all the medications you're taking to avoid potential interactions. They can help adjust your treatment plan to ensure safety and effectiveness.

Does Atomoxetine have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Atomoxetine include dry mouth, loss of appetite, and trouble sleeping. These effects vary in frequency and severity. Serious side effects, like liver damage or increased heart rate, require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor. They can help determine if Atomoxetine is the cause and suggest appropriate actions.

Does Atomoxetine have any safety warnings?

Yes, Atomoxetine has important safety warnings. It can increase the risk of suicidal thoughts in children and adolescents, especially during the first few months of treatment. Watch for mood changes or unusual behavior. Atomoxetine may also cause liver damage, so report symptoms like yellowing of the skin or eyes. Not adhering to these warnings can lead to serious consequences. Always follow your doctor's advice and report any concerning symptoms immediately.

Is Atomoxetine addictive?

Atomoxetine is not considered addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Atomoxetine works by affecting certain chemicals in the brain to help manage symptoms of ADHD, which is attention deficit hyperactivity disorder. This mechanism doesn't lead to addiction. If you have concerns about medication dependence, discuss them with your doctor for reassurance and guidance.

Is Atomoxetine safe for the elderly?

Elderly individuals may be more sensitive to the effects of Atomoxetine. They might experience side effects like dizziness or changes in heart rate more frequently. It's important for older adults to be closely monitored by their doctor while taking this medication. Regular check-ups can help ensure the treatment is safe and effective. If you have concerns about using Atomoxetine as an older adult, discuss them with your healthcare provider.

Is it safe to drink alcohol while taking Atomoxetine?

It's best to avoid alcohol while taking Atomoxetine. Alcohol can increase the risk of side effects like dizziness or drowsiness. It may also interfere with the effectiveness of the medication. If you choose to drink occasionally, limit your alcohol intake and be aware of how your body responds. Talk with your doctor about alcohol use while taking Atomoxetine for personalized advice based on your health situation.

Is it safe to exercise while taking Atomoxetine?

You can exercise while taking Atomoxetine, but be aware of how your body responds. This medication can sometimes cause dizziness or changes in heart rate. If you feel lightheaded or notice unusual fatigue during exercise, slow down or stop and rest. Stay hydrated and avoid strenuous activities if you experience side effects. Most people can maintain their regular exercise routine, but consult your doctor if you have concerns.

Is it safe to stop Atomoxetine?

It's important to talk with your doctor before stopping Atomoxetine. This medication is often used long-term for managing ADHD, which is attention deficit hyperactivity disorder. Stopping suddenly can cause symptoms to return or worsen. Your doctor may suggest gradually reducing the dose to minimize any potential withdrawal effects. Always follow your doctor's guidance to ensure a safe and effective treatment plan.

What are the most common side effects of Atomoxetine?

Side effects are unwanted reactions to a medication. Common side effects of Atomoxetine include dry mouth, loss of appetite, and trouble sleeping. These effects vary from person to person. If you notice new symptoms after starting Atomoxetine, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication. They can help determine if the side effects are related to Atomoxetine and suggest ways to manage them.

Who should avoid taking Atomoxetine?

Atomoxetine should not be used if you have a known allergy to it or its ingredients. It's also contraindicated in people with narrow-angle glaucoma, which is a type of eye condition, and those who have taken a monoamine oxidase inhibitor (MAOI) within the last 14 days. These conditions can lead to severe risks if Atomoxetine is used. Always consult your doctor about any health concerns before starting this medication.