Atazanavir
.svg)
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Protease Inhibitor
Controlled Drug Substance
No
atazanavir
Summary
Atazanavir is used to treat HIV infection, which is a virus that attacks the immune system. It helps control the virus, boosting the immune system and reducing the risk of developing AIDS, which is a severe stage of HIV infection.
Atazanavir works by inhibiting a virus enzyme called protease, which is needed for HIV to multiply. By blocking this enzyme, it helps control the virus in your body, boosting your immune system and managing HIV infection effectively.
The usual starting dose of Atazanavir for adults is 300 mg once daily, taken with food. It is often combined with ritonavir, which is another medication that boosts its effectiveness. Always follow your doctor's specific dosing instructions.
Common side effects of Atazanavir include nausea, which is feeling sick to your stomach, jaundice, which is yellowing of the skin or eyes, and rash, which is a change in the skin's appearance. If you notice any new or worsening symptoms, contact your doctor.
Atazanavir can cause liver problems, so regular liver function tests are recommended. It may also cause heart rhythm changes, known as QT prolongation, which can be serious. Do not take Atazanavir if you are allergic to it or have severe liver problems.
Indications and Purpose
How does Atazanavir work?
Atazanavir works by inhibiting a virus enzyme called protease, which is needed for HIV to multiply. By blocking this enzyme, Atazanavir helps control the virus in your body. Think of it like putting a lock on a door to prevent unwanted guests from entering. This action helps boost your immune system and manage HIV infection effectively.
Is Atazanavir effective?
Atazanavir is effective in treating HIV infection. It works by inhibiting a virus enzyme, which helps control the virus in your body. Clinical studies show that Atazanavir effectively reduces viral load and increases CD4 cell counts, which are important for a healthy immune system. It is often used in combination with other antiretroviral medications for the best results.
What is Atazanavir?
Atazanavir is an antiretroviral medication used to treat HIV infection. It belongs to a class of drugs called protease inhibitors, which work by blocking a virus enzyme needed for HIV to multiply. This helps control the virus in your body and boosts your immune system. Atazanavir is often used in combination with other antiretroviral medications to effectively manage HIV.
Directions for Use
For how long do I take Atazanavir?
Atazanavir is usually a long-term medication for managing HIV infection. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping this medication without medical advice could cause your condition to worsen. Always talk with your doctor before changing or stopping your Atazanavir treatment.
How do I dispose of Atazanavir?
Dispose of Atazanavir by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options aren't available, you can throw it in the trash at home. First, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. This helps prevent accidental ingestion by children or pets.
How do I take Atazanavir?
Take Atazanavir exactly as your doctor prescribes. It's usually taken once daily with food to help your body absorb it better. Swallow the capsules whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Avoid taking antacids within two hours of Atazanavir, as they can affect absorption.
How long does it take for Atazanavir to start working?
Atazanavir starts working in your body shortly after you take it, but it may take several weeks to see significant changes in your viral load and CD4 cell count. These are indicators of how well your immune system is functioning. Regular blood tests will monitor these levels. How quickly Atazanavir works can depend on your overall health and adherence to the medication.
How should I store Atazanavir?
Store Atazanavir at room temperature, away from moisture and light. Keep it in its original container with the lid tightly closed. Do not store it in the bathroom, where humidity can affect the medication. Always keep Atazanavir out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any expired medication properly.
What is the usual dose of Atazanavir?
The usual starting dose of Atazanavir for adults is 300 mg once daily, taken with food. It is often combined with another medication called ritonavir to boost its effectiveness. Dose adjustments may be necessary for people with liver problems or those taking certain other medications. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can Atazanavir be taken safely while breastfeeding?
Atazanavir is not recommended while breastfeeding. It can pass into breast milk and may harm the baby. HIV can also be transmitted through breast milk. If you are taking Atazanavir, talk with your doctor about alternative feeding options for your baby to ensure their safety and health.
Can Atazanavir be taken safely while pregnant?
Atazanavir can be used during pregnancy, but it should be done under the guidance of a doctor. The benefits of controlling HIV in the mother often outweigh potential risks to the baby. However, there is limited information on its safety during pregnancy. Always discuss with your doctor to ensure the best treatment plan for you and your baby.
Can I take Atazanavir with other prescription drugs?
Atazanavir can interact with several medications, including proton pump inhibitors like omeprazole, which can reduce its effectiveness. It also interacts with certain cholesterol-lowering drugs and anticonvulsants, increasing the risk of side effects. Always inform your doctor about all medications you take to avoid harmful interactions and ensure your treatment is effective.
Does Atazanavir have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Atazanavir include nausea, jaundice, and rash. Serious effects can include liver problems and heart rhythm changes. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these are related to Atazanavir and advise on the best course of action.
Does Atazanavir have any safety warnings?
Yes, Atazanavir has important safety warnings. It can cause liver problems, so regular liver function tests are recommended. It may also cause heart rhythm changes, known as QT prolongation, which can be serious. If you experience symptoms like dizziness or fainting, seek medical help. Atazanavir can also increase bilirubin levels, leading to jaundice, which is yellowing of the skin or eyes. Always follow your doctor's advice and report any unusual symptoms.
Is Atazanavir addictive?
Atazanavir is not addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Atazanavir works by inhibiting a virus enzyme, which doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is Atazanavir safe for the elderly?
Elderly patients may be more vulnerable to side effects of Atazanavir, such as liver problems or heart rhythm changes. They may also have other health conditions or take multiple medications, increasing the risk of interactions. Regular monitoring and dose adjustments may be necessary. Always consult your doctor to ensure Atazanavir is safe for your specific health needs.
Is it safe to drink alcohol while taking Atazanavir?
It's best to limit alcohol while taking Atazanavir. Alcohol can increase the risk of liver problems, which Atazanavir can also cause. Drinking alcohol may worsen side effects like nausea or dizziness. If you choose to drink, do so in moderation and talk with your doctor about your alcohol use to get personalized advice.
Is it safe to exercise while taking Atazanavir?
Yes, you can exercise while taking Atazanavir. Regular physical activity is beneficial for overall health. However, Atazanavir can cause side effects like dizziness or fatigue, which might affect your exercise capacity. Listen to your body and avoid strenuous activities if you feel unwell. Stay hydrated and talk with your doctor if you have concerns about exercising while on this medication.
Is it safe to stop Atazanavir?
Stopping Atazanavir suddenly can lead to a rebound in your viral load, which is the amount of virus in your blood. This can worsen your condition and increase the risk of developing drug resistance. Always talk with your doctor before stopping Atazanavir. They can guide you on how to safely discontinue or switch medications if needed.
What are the most common side effects of Atazanavir?
Side effects are unwanted reactions to a medication. Common side effects of Atazanavir include nausea, jaundice, and rash. These occur in varying frequencies among users. If you experience new symptoms after starting Atazanavir, they might be temporary or unrelated to the medication. Always talk with your doctor before stopping any medication.
Who should avoid taking Atazanavir?
Do not take Atazanavir if you are allergic to it or its ingredients. It is contraindicated in patients with severe liver problems. Atazanavir should not be used with certain medications like rifampin, which can reduce its effectiveness. Always consult your doctor about any other medications you are taking to avoid harmful interactions.
Forms / Brands
