Aspirin

Rheumatoid Arthritis, Pain ... show more

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

NO

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Pharmaceutical Class

Nonsteroidal Anti-inflammatory Drug and Platelet Aggregation Inhibitor

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Controlled Drug Substance

NO

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Drug Ingredient

Aspirin

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Summary

  • Aspirin is used for pain relief, reducing inflammation, and preventing blood clots. It can help with minor aches and pains like headaches, muscle aches, arthritis, and toothaches. It's also used for cardiovascular protection in people at risk of heart attacks, strokes, or blood clots.

  • Aspirin works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2) which help produce prostaglandins, chemicals that cause inflammation, pain, and fever. By blocking these, Aspirin reduces pain, inflammation, and prevents blood platelets from clumping together, reducing the risk of blood clots.

  • Aspirin is typically taken orally with a full glass of water, with or without food. It usually starts working within 30 minutes to 1 hour after administration. Always follow your doctor's guidance for proper use.

  • Aspirin can cause gastrointestinal issues like stomach ulcers, bleeding or irritation. It can also increase the risk of internal bleeding, especially when combined with blood thinners. Some people might experience side effects like stomach upset or fluid retention.

  • Aspirin should be avoided by individuals who are allergic to it, have a history of gastrointestinal bleeding or ulcers, certain bleeding disorders, or are pregnant. It should also be avoided in children under 16 with viral infections due to the risk of Reyes syndrome. Always consult your doctor before taking Aspirin.

Indications and Purpose

How does Aspirin work?

Aspirin works by inhibiting the enzyme cyclooxygenase, which reduces the production of prostaglandins and thromboxanes. This action helps decrease inflammation, pain, fever, and blood clot formation.

How does one know if Aspirin is working?

The benefit of aspirin is evaluated by its effectiveness in relieving symptoms like pain and fever, and in preventing cardiovascular events. Regular medical check-ups and monitoring of symptoms help assess its ongoing benefit and safety for the individual.

Is Aspirin effective?

Aspirin is effective in relieving pain, reducing fever, and preventing blood clots. It works by inhibiting the production of substances that cause inflammation and clotting. Its effectiveness in preventing heart attacks and strokes in certain individuals is well-documented.

What is Aspirin?

Aspirin is commonly used to relieve pain, reduce fever, and prevent blood clots. It works by inhibiting the production of substances that cause inflammation and clotting. Aspirin is also used to reduce the risk of heart attacks and strokes in certain individuals.

What is Aspirin used for?

Aspirin is indicated for relieving pain and inflammation in conditions like arthritis, reducing fever, and preventing heart attacks and strokes in individuals at risk. It is also used in certain rheumatologic conditions and to prevent complications in specific heart conditions.

Directions for Use

For how long do I take Aspirin?

Aspirin can be used for short-term relief of pain or fever, typically not exceeding 10 days for pain or 3 days for fever without consulting a doctor. For cardiovascular protection, it may be used long-term as prescribed by a healthcare provider.

How do I dispose of Aspirin?

If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.

How do I take Aspirin?

Aspirin can be taken with or without food, but taking it with food or a full glass of water may help reduce stomach upset. There are no specific food restrictions, but avoid alcohol to reduce the risk of stomach bleeding.

How long does it take for Aspirin to start working?

Aspirin typically starts working within 30 minutes to 1 hour after ingestion for pain relief. For cardiovascular protection, its effects on blood clotting can begin within a few hours.

How should I store Aspirin?

Store aspirin in its original container, tightly closed, at room temperature, away from excess heat and moisture. Keep it out of reach of children. Dispose of tablets with a strong vinegar smell, as this indicates they may have degraded.

What is the usual dose of Aspirin?

For adults, the usual dose of aspirin for pain relief is 300-1000 mg every 4 to 6 hours, not exceeding 4 grams per day. For children, aspirin is generally not recommended due to the risk of Reye's syndrome, but if prescribed, the dose should be determined by a doctor.

Warnings and Precautions

Can Aspirin be taken safely while breastfeeding?

Aspirin is generally not recommended while breastfeeding due to the risk of Reye's syndrome in infants. If necessary, low doses may be used under medical supervision. Consult your doctor for personalized advice.

Can Aspirin be taken safely while pregnant?

Low-dose aspirin may be used during pregnancy under medical supervision, but doses above 81 mg can harm the fetus, especially after 20 weeks. High doses can cause complications during delivery. Pregnant women should consult their doctor before using aspirin.

Can I take Aspirin with other prescription drugs?

Aspirin can interact with blood thinners like warfarin, increasing bleeding risk. It may also interact with NSAIDs, certain diabetes medications, and ACE inhibitors. Always inform your doctor about all medications you are taking to avoid harmful interactions.

Can I take Aspirin with vitamins or supplements?

Aspirin can interact with certain supplements, like fish oil and vitamin E, which may increase bleeding risk. There are no known nutrient depletions caused by aspirin. Always inform your healthcare provider about all supplements you're taking to avoid potential interactions. They can provide guidance on safe use and monitor for any adverse effects.

Does Aspirin have adverse effects?

Adverse effects are unwanted or harmful effects caused by a medicine. For aspirin, common adverse effects include stomach pain, heartburn, and nausea. Serious but rare effects can include bleeding in the stomach or brain, which needs immediate medical attention. If you notice any new or unusual symptoms, it's important to talk to your healthcare provider before stopping the medicine.

Does Aspirin have any safety warnings?

Aspirin has safety warnings, including the risk of stomach bleeding, especially if taken with alcohol or other blood thinners. It can also cause allergic reactions in some people. Symptoms to watch for include stomach pain, black stools, or unusual bleeding. If you experience these, seek medical help immediately. Always follow your doctor's advice and read the label for any additional warnings.

Is Aspirin addictive?

Aspirin is not addictive and has no known potential for dependence. It does not cause physical or psychological dependence, so there are no warning signs of addiction to watch for. You can use aspirin as directed by your healthcare provider without worrying about addiction.

Is Aspirin safe for the elderly?

Elderly patients are more susceptible to the adverse effects of aspirin, such as gastrointestinal bleeding and kidney issues. They should use aspirin under medical supervision, especially if they have a history of ulcers or are taking other medications that increase bleeding risk.

Is it safe to drink alcohol while taking Aspirin?

Drinking alcohol while taking aspirin can increase the risk of stomach bleeding. If you consume three or more alcoholic drinks every day, consult your doctor before using aspirin. Occasional or moderate drinking may still pose a risk, so it's best to discuss with a healthcare provider.

Is it safe to exercise while taking Aspirin?

Aspirin does not typically limit the ability to exercise. However, if you experience any side effects like dizziness or stomach pain, it may affect your ability to exercise comfortably. Consult your doctor if you have concerns about exercising while taking aspirin.

Is it safe to stop Aspirin?

Stopping aspirin suddenly can be risky, especially if it's used for long-term management of conditions like heart disease or stroke prevention. Abruptly stopping can increase the risk of a heart attack or stroke. There are no withdrawal symptoms, but the protective effects stop. Always consult your doctor before stopping aspirin to ensure it's safe and to discuss any potential risks.

What are the most common side effects of Aspirin?

A side effect is an unwanted effect of a medicine. Common side effects of aspirin include stomach pain, heartburn, nausea, and dizziness. These effects are usually mild and may go away on their own. It's important to remember that new symptoms might not be related to the medicine. Always talk to your healthcare provider before stopping aspirin to ensure it's safe.

Who should avoid taking Aspirin?

Aspirin should not be used by individuals with allergies to it, those with bleeding disorders, or those who have had stomach ulcers. It should be used cautiously in people with asthma or liver and kidney issues. Pregnant women should avoid high doses, especially in the third trimester.