Alprazolam
Agoraphobia, Depressive Disorder ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Benzodiazepine
Controlled Drug Substance
YES
Alprazolam
Learn more about this medicine -
Click HereSummary
Alprazolam is used to treat anxiety and panic disorders. It helps manage symptoms such as excessive worry, restlessness, and panic attacks.
Alprazolam works by enhancing the effects of GABA, a neurotransmitter that promotes calmness in the brain. This action helps reduce symptoms of anxiety and panic attacks.
The usual daily dose of Alprazolam for adults starts at 0.25 to 0.5 mg taken three times a day. The dose may be adjusted by a doctor based on individual needs but it usually does not exceed 4 mg per day.
Common side effects of Alprazolam include drowsiness, dizziness, and fatigue. Serious adverse effects, though rare, can include severe allergic reactions, respiratory depression, and dependence.
Alprazolam should not be used by individuals with a history of allergic reactions to benzodiazepines, severe respiratory issues, or acute narrow-angle glaucoma. It can cause dependence and withdrawal symptoms. Avoid alcohol and consult your doctor about other medications you are taking.
Indications and Purpose
What is Alprazolam used for?
Alprazolam is prescribed to treat anxiety and panic disorders. It helps by calming the nervous system, reducing symptoms like excessive worry and panic attacks. It may be used alone or with other treatments, depending on the individual's needs.
How does Alprazolam work?
Alprazolam works by enhancing the effects of a neurotransmitter called GABA in the brain. This action helps to calm the nervous system, reducing symptoms of anxiety and panic. It's like turning down the volume on an overactive brain, helping you feel more relaxed.
Is Alprazolam effective?
Alprazolam is primarily used to treat anxiety and panic disorders. It works by enhancing the effects of a natural chemical in the brain called GABA, which has a calming effect. Clinical trials have shown that Alprazolam is effective in reducing symptoms of anxiety and panic attacks.
How does one know if Alprazolam is working?
Alprazolam is used to treat anxiety and panic disorders. You may notice a reduction in symptoms such as excessive worry, restlessness, and panic attacks. Effectiveness is monitored by symptom improvement. Regular follow-ups with your healthcare provider can help assess the medication's effectiveness.
Directions for Use
What is the usual dose of Alprazolam?
The usual starting dose of Alprazolam for adults is 0.25 to 0.5 mg taken three times daily. The dose may be adjusted based on individual response and tolerance. The maximum recommended dose is 4 mg per day. For elderly patients, a lower starting dose is often recommended. Always follow your healthcare provider's instructions for dosing.
How do I take Alprazolam?
Take Alprazolam exactly as prescribed by your healthcare provider. It is usually taken by mouth, with or without food, two to four times daily. Avoid alcohol and grapefruit juice while taking this medication. Follow your healthcare provider's instructions for timing and frequency.
For how long do I take Alprazolam?
Alprazolam is typically used for short-term treatment of anxiety and panic disorders. The duration of use varies based on individual needs and response to treatment. It's crucial to follow your prescriber's instructions regarding the duration of use to avoid dependence and withdrawal symptoms.
How long does it take for Alprazolam to start working?
Alprazolam typically starts working within 1 to 2 hours after taking it, with peak effects occurring in 1 to 2 hours. Individual factors such as metabolism and other medications can affect onset time. Always follow your prescriber's instructions for this medication.
How should I store Alprazolam?
Store Alprazolam at room temperature, away from moisture and light. Keep it in a secure place out of reach of children. Avoid storing it in the bathroom or any damp area. Follow any specific storage instructions provided by your pharmacist.
Warnings and Precautions
Who should avoid taking Alprazolam?
Absolute contraindications for Alprazolam include allergies to the drug and acute narrow-angle glaucoma. Relative contraindications include respiratory depression and severe liver disease. Use caution in populations such as the elderly and those with a history of substance abuse. Always inform your healthcare provider of your medical history before starting Alprazolam.
Can I take Alprazolam with other prescription drugs?
Alprazolam has major interactions with other CNS depressants, such as opioids and alcohol, which can increase sedation and risk of overdose. It also interacts with certain antifungal medications and some antibiotics, which can increase Alprazolam levels in the blood. Always inform your healthcare provider about all medications you are taking to avoid potential interactions.
Can I take Alprazolam with vitamins or supplements?
Confirmed interactions with Alprazolam include supplements like St. John's Wort, which can decrease its effectiveness. There is no specific need for supplementation due to nutrient depletion by Alprazolam. Always inform your healthcare provider about all supplements you are taking to avoid potential interactions.
Can Alprazolam be taken safely while pregnant?
Alprazolam is not considered safe during pregnancy due to potential risks to the fetus, including withdrawal symptoms and birth defects. It is contraindicated, especially in the first trimester. Always consult a healthcare provider before starting any medication during pregnancy.
Can Alprazolam be taken safely while breastfeeding?
Alprazolam is excreted into breast milk and may affect the breastfed infant, causing sedation or feeding difficulties. It may also affect milk supply. It is generally considered inadvisable to use Alprazolam while breastfeeding. Consult your healthcare provider for personalized advice.
Is Alprazolam safe for the elderly?
Elderly patients may be more sensitive to the effects of Alprazolam, such as drowsiness and dizziness, which can increase the risk of falls. A lower starting dose is often recommended. It's important for elderly patients to follow their healthcare provider's instructions and report any new symptoms.
Is it safe to exercise while taking Alprazolam?
Most people tolerate Alprazolam well, and it should not limit your ability to exercise. However, due to potential drowsiness or dizziness, it's advisable to avoid strenuous activities until you know how the medication affects you. If you experience any unusual symptoms during exercise, consult your healthcare provider.
Is it safe to drink alcohol while taking Alprazolam?
It is not advisable to drink alcohol while taking Alprazolam. Alcohol can enhance the sedative effects of Alprazolam, leading to increased drowsiness, dizziness, and risk of overdose. This combination can impair your ability to perform tasks that require alertness, such as driving. It's best to avoid alcohol entirely while on this medication.
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