Alogliptin

Type 2 Diabetes Mellitus

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

NO

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Known Teratogen

NO

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Pharmaceutical Class

Dipeptidyl Peptidase 4 Inhibitor

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Controlled Drug Substance

NO

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Drug Ingredient

Alogliptin

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Summary

  • Alogliptin is used to manage blood sugar levels in adults with type 2 diabetes. It is not indicated for type 1 diabetes or diabetic ketoacidosis.

  • Alogliptin works by inhibiting an enzyme called DPP4, which increases the levels of hormones that help increase insulin release and decrease glucagon levels. This leads to better blood sugar control in people with type 2 diabetes.

  • The usual daily dose of Alogliptin for adults is 25 mg taken orally once a day. It is not recommended for use in pediatric patients.

  • Common side effects of Alogliptin include headache, stuffy or runny nose, and sore throat. Serious adverse effects can include pancreatitis, heart failure, and severe allergic reactions.

  • Important warnings for Alogliptin include the risk of pancreatitis, heart failure, and severe allergic reactions. It is contraindicated in patients with a history of serious hypersensitivity to the drug. Patients should be monitored for signs of liver injury and heart failure.

Indications and Purpose

Directions for Use

Warnings and Precautions