Acarbose
Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Alpha-Glucosidase Inhibitor
Controlled Drug Substance
NO

Acarbose
Summary
Acarbose is a medication used to manage blood sugar levels in people with type 2 diabetes.
Acarbose works by blocking enzymes in your intestines that break down carbohydrates into simple sugars. This slows down the breakdown of carbohydrates, helping to prevent spikes in your blood sugar levels after meals.
Acarbose is taken by mouth with the first bite of each main meal. The starting dose is usually 25 mg three times a day, but can be increased to 50 mg three times a day if needed. The maximum dose depends on your weight.
The most common side effects of Acarbose are digestive issues like gas, diarrhea, and stomach discomfort. These usually improve over time. Serious but rare side effects include liver problems, skin reactions, swelling, intestinal blockages, and low platelet count.
Acarbose can cause hypoglycemia, especially if taken with other diabetes medications. It's also not well understood how Acarbose affects fertility or its safety during pregnancy and breastfeeding. It's important to discuss these potential risks with your healthcare provider. Certain medications and supplements, like amoxicillin, corticosteroids, and vitamin C, can interact with Acarbose.
Indications and Purpose
How does Acarbose work?
Acarbose is a medication that helps manage blood sugar levels after eating. It works by blocking enzymes in the intestines that break down carbohydrates into simple sugars. By slowing down the breakdown of carbohydrates, acarbose helps prevent spikes in blood sugar levels after meals. Acarbose does not affect the enzyme that breaks down lactose, so it does not cause lactose intolerance.
Is Acarbose effective?
Acarbose has been shown to be effective in improving glycemic control in people with type 2 diabetes, and in reducing the risk of microvascular complications.
What is Acarbose?
Acarbose is a medication that is used to treat type 2 diabetes by slowing the digestion and absorption of carbohydrates in the body. It works by inhibiting enzymes that are involved in carbohydrate digestion, which helps to reduce the blood glucose levels after meals and improve overall blood glucose control.
Directions for Use
For how long do I take Acarbose?
Acarbose is typically taken long-term to manage type 2 diabetes, but the exact duration depends on your condition and your doctor's advice. Always follow your healthcare provider's instructions.
How do I dispose of Acarbose?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How do I take Acarbose?
Acarbose should be taken with meals that contain carbohydrates, with the first bite of food, and patients should follow a healthy diet and avoid high-carbohydrate foods.
How long does it take for Acarbose to start working?
Acarbose starts working as soon as it is taken, and its effects can be observed within 1-2 hours after a meal. However, the full effects of the medication may not be seen for several weeks, as it takes time for the body to adjust to the new medication.
How should I store Acarbose?
Acarbose should be stored at room temperature in a tightly closed container, protected from moisture, heat, and light. It should be used before the expiration date and disposed of properly.
What is the usual dose of Acarbose?
The usual starting dose for adults is typically 50 mg taken once daily. Depending on the patient's response, the dose may be adjusted by the healthcare provider. The maximum recommended dose is usually 100 mg per day. For secondary indications, such as treating high blood pressure, the dose might differ, and a healthcare provider will provide specific instructions. For special populations like children or the elderly, dose adjustments are often necessary to ensure safety and effectiveness. It's crucial to follow the healthcare provider's instructions for dosing to avoid any potential side effects or complications.
Warnings and Precautions
Can Acarbose be taken safely while breastfeeding?
The safety of Acarbose during breastfeeding is unknown, and breastfeeding mothers should avoid taking the medication unless the potential benefits outweigh the potential risks.
Can Acarbose be taken safely while pregnant?
Acarbose is a Pregnancy Category B drug, but there is limited information available on its safety during pregnancy, and more research is needed.
Can I take Acarbose with other prescription drugs?
Antibiotics: Some antibiotics, such as amoxicillin, can increase the risk of hypoglycemia when taken with Acarbose.
Corticosteroids: Corticosteroids, such as prednisone, can increase blood glucose levels and reduce the effectiveness of Acarbose.
Insulin and sulfonylureas: Acarbose can increase the risk of hypoglycemia when taken with insulin or sulfonylureas, such as glipizide and glyburide.
Does Acarbose have adverse effects?
Adverse effects, which are unwanted or harmful effects caused by a medicine, can vary from mild to severe. For this medicine, common adverse effects might include nausea, headache, dizziness, fatigue, and dry mouth. These effects can occur in some people, but not everyone will experience them. Rare but serious adverse effects could include severe allergic reactions, which might cause difficulty breathing or swelling of the face and throat, and require immediate medical attention. It's important to report any new or worsening symptoms to a healthcare provider. Never stop taking a medicine without first consulting with a healthcare professional, as they can provide guidance on how to manage side effects safely.
Does Acarbose have any safety warnings?
To determine if a medicine has safety warnings, you should first check the prescription information. Common safety warnings may include allergic reactions, which occur when the body's immune system reacts to the medicine. Symptoms to watch for include rash, itching, swelling, or difficulty breathing. Another warning could be related to liver damage, which can happen if the medicine is processed by the liver. Signs to monitor include yellowing of the skin or eyes, dark urine, or severe fatigue. Additionally, some medicines may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. If you experience these symptoms, it's important to avoid such activities. Always consult with a healthcare professional for personalized advice and to understand all potential risks associated with a specific medicine.
Is Acarbose addictive?
This medicine has no known potential for dependence or addiction. It is considered safe in terms of habit-forming potential. Therefore, there is no need to worry about developing a physical or psychological dependence on this medication. However, it is always important to follow the prescribed dosage and instructions provided by your healthcare provider to ensure safe and effective use. If you have any concerns or experience any unusual symptoms while taking this medicine, it is advisable to consult with your healthcare provider for further guidance.
Is Acarbose safe for the elderly?
Acarbose can be used in the elderly, but caution is needed due to possible side effects and changes in kidney or liver function. Always follow your doctor’s guidance.
Is it safe to drink alcohol while taking Acarbose?
Most people tolerate this medicine well, and occasional alcoholic drinks should not affect the way this medicine works. There are no well-established interactions between this medicine and alcohol. Therefore, moderate alcohol consumption is generally considered safe while taking this medicine. However, it's important to be cautious, as alcohol can sometimes interfere with the effectiveness of medications or exacerbate side effects. If you experience any unusual symptoms or side effects, it may be best to limit or avoid alcohol. As a general guideline, sticking to the recommended alcohol limits, such as no more than one drink per day for women and two for men, is advisable. Always consult with your healthcare provider for personalized advice.
Is it safe to exercise while taking Acarbose?
To determine if it's safe to exercise while taking this medicine, we first need to assess if it causes symptoms that might limit your exercise capacity, physical strength, or endurance. If the medicine typically limits the ability to exercise, it might cause symptoms like dizziness, fatigue, or shortness of breath during physical activity. If these symptoms occur, it's important to take precautions. You might need to modify your exercise routine by avoiding strenuous activities or high-impact sports. However, if there is no specific information available about the relationship between this medicine and exercise, most people tolerate this medicine well, and it should not limit your ability to exercise. Always consult with your healthcare provider for personalized advice.
Is it safe to stop Acarbose?
To determine if it's safe to stop a medicine, first consider its purpose. If it's for managing a chronic condition like hypertension or diabetes, stopping it suddenly can lead to serious health risks, such as uncontrolled blood pressure or blood sugar levels. For medicines providing symptomatic relief or treating temporary conditions, stopping might lead to the return of symptoms or incomplete treatment of the condition. Some medicines can cause withdrawal symptoms or rebound effects, where symptoms return worse than before. Abruptly stopping certain medicines can be life-threatening, especially if they affect the heart or brain. Always consult a doctor before stopping any medicine to ensure it's done safely and appropriately.
What are the most common side effects of Acarbose?
A side effect is an unwanted or unexpected symptom caused by a medicine. For this medicine, common side effects may include nausea, which is feeling sick to your stomach, and headache, which is pain in the head. Other side effects can be dizziness, which is feeling lightheaded, and fatigue, which is feeling very tired. Some people might also experience dry mouth, which is when your mouth feels unusually dry. The frequency of these side effects can vary, but they are generally considered common. It's important to remember that when starting a new medicine, you might notice new symptoms. These could be unrelated to the medicine, temporary, or due to another health issue. Always talk to your healthcare provider before stopping any medicine, as they can help you understand the risks and benefits.
Who should avoid taking Acarbose?
Hypoglycemia: Acarbose can cause hypoglycemia (low blood glucose levels) in some people, especially if taken with other diabetes medications. Patients should monitor their blood glucose levels closely and report any signs of hypoglycemia to their healthcare provider.
Digestive issues: Acarbose can cause digestive issues such as bloating, flatulence, and diarrhea, especially in the first few weeks of treatment. Patients should report any digestive symptoms to their healthcare provider.