Acamprosate

Alcoholism

Drug Status

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Government Approvals

US(FDA), UK(BNF)

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WHO Essential Medicine

YES

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Known Teratogen

NO

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Pharmaceutical Class

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Controlled Drug Substance

No

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Drug Ingredient

acamprosate

Summary

  • Acamprosate is used to help people maintain abstinence from alcohol, which means staying alcohol-free. It is not used to treat withdrawal symptoms or as a standalone treatment but works best when combined with counseling and support.

  • Acamprosate works by restoring the balance of certain brain chemicals, which are disrupted by alcohol use. This helps reduce cravings and the urge to drink, making it easier for people to stay alcohol-free.

  • The usual dose for adults is two 333 mg tablets taken three times a day, usually with meals. Your doctor may adjust the dose based on your specific needs and health condition.

  • Common side effects of Acamprosate include diarrhea, which affects about 10% of users. Other less common effects are nausea, vomiting, and stomach pain. These effects are usually mild and can be managed with food.

  • Acamprosate should not be used in people with severe kidney problems, which affect organs that filter waste from your blood. It's also contraindicated in those allergic to it or its ingredients. Always consult your doctor before starting Acamprosate.

Indications and Purpose

How does Acamprosate work?

Acamprosate works by restoring the balance of certain brain chemicals disrupted by alcohol use. It helps reduce cravings and the urge to drink. Think of it like resetting a balance scale in your brain, helping you maintain abstinence from alcohol. This makes it a helpful tool in recovery when used with counseling.

Is Acamprosate effective?

Acamprosate is effective in helping people maintain abstinence from alcohol. It works by restoring the balance of certain brain chemicals disrupted by alcohol use. Studies show that Acamprosate can significantly increase the chances of staying alcohol-free when used alongside counseling and support.

What is Acamprosate?

Acamprosate is a medication used to help people maintain abstinence from alcohol. It belongs to a class of drugs called alcohol abstinence aids. Acamprosate works by restoring the balance of certain brain chemicals disrupted by alcohol use. It's used alongside counseling and support to help people stay alcohol-free.

Directions for Use

For how long do I take Acamprosate?

Acamprosate is usually taken long-term to help maintain abstinence from alcohol. The duration of use depends on your progress and doctor's advice. It's important to follow your doctor's instructions and not stop taking Acamprosate without consulting them, as this could affect your recovery.

How do I dispose of Acamprosate?

Dispose of Acamprosate by taking it to a drug take-back program or collection site at a pharmacy or hospital. If unavailable, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away in the trash. This helps prevent harm to people and the environment.

How do I take Acamprosate?

Take Acamprosate as prescribed by your doctor, usually three times a day. It's best to take it with meals to help your body absorb it better. Swallow the tablets whole; do not crush or chew them. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double up on doses.

How long does it take for Acamprosate to start working?

Acamprosate begins working in your body shortly after you start taking it, but the full effects may take several weeks to become noticeable. The time it takes to work can vary based on individual factors like your overall health and adherence to the treatment plan. Consistent use as prescribed is important for the best results.

How should I store Acamprosate?

Store Acamprosate at room temperature, away from moisture and light. Keep it in a tightly closed container. Avoid storing it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.

What is the usual dose of Acamprosate?

The usual dose of Acamprosate for adults is two 333 mg tablets taken three times a day. This dose is typically taken with meals. Your doctor may adjust your dose based on your specific needs and health condition. Always follow your doctor's instructions regarding dosage and frequency.

Warnings and Precautions

Can Acamprosate be taken safely while breastfeeding?

The safety of Acamprosate while breastfeeding is not well-established. It's unclear if the medication passes into breast milk. Discuss with your doctor if you're breastfeeding or planning to breastfeed. Your doctor can help determine the safest way to manage your health while nursing.

Can Acamprosate be taken safely while pregnant?

The safety of Acamprosate during pregnancy is not well-established. It's important to discuss with your doctor if you're pregnant or planning to become pregnant. Your doctor can help determine the safest way to manage your health during pregnancy.

Can I take Acamprosate with other prescription drugs?

Acamprosate has no major drug interactions, but it's important to inform your doctor about all medications you're taking. This helps prevent any potential interactions and ensures your treatment is safe and effective. Always follow your doctor's advice regarding medication use.

Does Acamprosate have adverse effects?

Adverse effects are unwanted reactions to a medication. Common adverse effects of Acamprosate include diarrhea, which affects about 10% of users. Other effects like nausea, vomiting, or stomach pain are less common. Serious effects are rare but can include severe allergic reactions. If you notice any new or worsening symptoms, contact your doctor.

Does Acamprosate have any safety warnings?

Yes, Acamprosate has safety warnings. It should not be used in people with severe kidney problems, which affect organs that filter waste from your blood. If you experience symptoms like severe diarrhea, which can lead to dehydration, contact your doctor. Not adhering to these warnings can lead to serious health issues.

Is Acamprosate addictive?

Acamprosate is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. Acamprosate works by affecting brain chemicals to help maintain alcohol abstinence, but it doesn't create cravings or a need to take more than prescribed. If you have concerns about medication dependence, Acamprosate doesn't carry this risk.

Is Acamprosate safe for the elderly?

Elderly individuals may be more sensitive to the effects of medications, including Acamprosate. It's important for older adults to be monitored closely by their doctor while taking this medication. The doctor may adjust the dose based on kidney function and overall health to ensure safety.

Is it safe to drink alcohol while taking Acamprosate?

No, you should not drink alcohol while taking Acamprosate. This medication is used to help maintain abstinence from alcohol. Drinking alcohol while on Acamprosate can interfere with its effectiveness and your recovery process. Always follow your doctor's advice regarding alcohol use.

Is it safe to exercise while taking Acamprosate?

Yes, it's safe to exercise while taking Acamprosate. There are no known side effects that limit exercise capacity. However, if you feel dizzy or unwell during physical activity, stop and rest. Always stay hydrated and consult your doctor if you have concerns about your exercise routine.

Is it safe to stop Acamprosate?

Acamprosate is usually taken long-term to help maintain alcohol abstinence. Stopping it suddenly may increase the risk of returning to drinking. There are no withdrawal symptoms associated with stopping Acamprosate, but always talk with your doctor before making any changes to your medication regimen.

What are the most common side effects of Acamprosate?

Side effects are unwanted reactions to a medication. Common side effects of Acamprosate include diarrhea, which affects about 10% of people taking it. Other side effects like nausea, vomiting, or stomach pain are less common. If you notice new symptoms after starting Acamprosate, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.

Who should avoid taking Acamprosate?

Acamprosate should not be used in people with severe kidney problems, which affect organs that filter waste from your blood. It's also contraindicated in those allergic to it or its ingredients. Always consult your doctor about any concerns or conditions before starting Acamprosate.