xeremal R

Xeremal-R 50mg Tablet contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases Belonging to the artemisinin class of medications,holds a place on the World Health Organization''s List of Essential Medicines

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA) This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels

While generally welltolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester It is generally safe for use in children, with adjustments in dosing for those under 20 kg Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action The timing and severity of the missed dose will be considered to determine the most suitable response

Available in 2 variations

Xeremal-R 60mg Injection

Artesunate (60mg)

vial of 1 Powder for Injection

MRP : ₹175

Xeremal-R 50mg Tablet

Artesunate (50mg)

strip of 10 tablets

MRP : ₹238

Related Faqs

Is Malart banned in India?

In India the accessibility of certain medications is strictly controlled and monitored One such medicine requiring a doctors prescription is available exclusively through this regulated process This practice aims to ensure the safety and wellbeing of individuals by preventing the misuse or improper administration of potentially harmful drugs By implementing these restrictions the government and medical authorities aim to minimize the risks associated with selfmedication and encourage individuals to consult a healthcare professional for proper diagnosis and prescription This system plays a crucial role in safeguarding public health and upholding ethical standards in the pharmaceutical industry Therefore if one wishes to obtain this particular medicine in India it is essential to consult a qualified doctor who can assess the individuals condition and prescribe the appropriate treatment By following this established protocol individuals can receive the necessary medication while also prioritizing their health and wellbeing

How does Maxinate work?

The mechanism of action of this substance involves the generation of free radicals which effectively exterminate the Plasmodium parasite responsible for causing malaria By producing these highly reactive particles this substance exhibits a potent antimalarial effect The free radicals generated upon administration of this substance target the vital structures and metabolic processes of the malarial parasite leading to its eradication By disrupting the parasites normal functioning this substance effectively halts the progression of the disease and promotes the elimination of the infection This unique mechanism of action sets this substance apart as an efficient and effective option in the fight against malaria Its ability to specifically target and eliminate the Plasmodium parasite showcases its potential to combat this widespread and lifethreatening disease By harnessing the power of free radicals this substance offers a promising strategy for inhibiting the growth and survival of the malarial parasite ultimately contributing to the global efforts to control and eliminate malaria

Where does Arinatem come from?

Artemisinin a compound with potent antimalarial properties is sourced from the Artemisinin tree This tree also known as sweet wormwood or Qing Hao in traditional Chinese medicine has been used for centuries in the treatment of various ailments The extraction of artemisinin from the leaves of this tree revolutionized the field of malaria treatment offering a more effective and fasteracting solution compared to conventional drugs Artemisinins remarkable effectiveness against malaria is attributed to its unique chemical structure which allows it to target and eliminate the malaria parasites in the blood When ingested artemisinin reacts with iron from the parasites producing free radicals that damage the parasites cellular structures leading to their demise This mode of action sets artemisinin apart from other antimalarial drugs and has contributed to its widespread use in combating malaria particularly in regions where drug resistance has become a significant concern In addition to its antimalarial properties artemisinin has shown promising potential in treating various other diseases and conditions Recent studies have indicated its effectiveness against certain types of cancer including leukemia and breast cancer It has also demonstrated antiinflammatory immunosuppressive and antiviral activities Although further research is needed to harness its full therapeutic potential artemisinins versatility and unique mode of action make it a promising candidate for future drug development Overall the derivation of artemisinin from the Artemisinin tree has led to significant advancements in the treatment of malaria and holds promise for tackling other diseases Its natural origin and potent properties make it a valuable resource in the ongoing battle against global health challenges

Is Genuate banned in India?

In India the availability of certain medications is regulated requiring a doctors prescription to obtain them This measure ensures the safety and appropriate usage of these drugs By implementing this system the government aims to protect the public from potential risks associated with selfmedication and inappropriate use of medications While this may seem inconvenient for some it is a necessary step to safeguard the health and wellbeing of individuals in the country Having a doctors prescription serves several purposes Firstly it helps to prevent the misuse or abuse of medications that can have severe consequences on ones health Secondly it allows medical professionals to evaluate the patients condition and history ensuring that the prescribed medication aligns with their specific needs Additionally prescriptions enable doctors to monitor the patients progress and make any necessary adjustments to the treatment plan The process of obtaining a prescription is relatively straightforward Individuals seeking medication must schedule an appointment with a qualified healthcare provider who will assess their medical condition and recommend appropriate treatment Following the consultation the doctor will issue a prescription that can be presented to a licensed pharmacist to obtain the prescribed medication This system ensures that individuals receive the appropriate treatment and minimizes the risks associated with selfdiagnosis and selfmedication

Is T Nate banned in India?

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How does Artesar work?

The mechanism of action of this particular compound involves the production of free radicals which have the capacity to effectively target and eliminate the malarial parasite known as Plasmodium By generating these highly reactive molecules this substance is able to disrupt vital processes within the parasite ultimately leading to its demise The production of free radicals is a critical step in the chain of events that result in the destruction of the malarial parasite This compounds unique ability to generate these radicals distinguishes it as an effective weapon against the Plasmodium parasite offering a promising approach for combating malaria As the free radicals are unleashed they directly attack specific targets within the parasite such as key proteins or cell membranes interfering with essential biological processes Consequently the malarial parasite is unable to survive leading to its complete eradication This innovative mechanism of action places this compound at the forefront of antimalarial treatments showcasing its potential for contributing to the global efforts in controlling and ultimately eliminating malaria

Written By:

DRx. Ayush RajMBA in Pharmaceuticals Marketing and Management

Published At: Dec 11, 2024

Updated At: Dec 30, 2024

Reviewed By:

DRx Ashwani SinghMaster in Pharmacy

Published At: Dec 11, 2024

Updated At: Dec 30, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

Find us at:

xeremal R

Prescription Required

Manufacturer :

Haledew Remedies

Composition :

artesunate

MRP :

₹175 - ₹238