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Malicure 50mg Tablet

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Malicure 50mg Tablet

Malicure 50mg Tablet contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases Belonging to the artemisinin class of medications,holds a place on the World Health Organization''s List of Essential Medicines

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA) This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels

 

While generally welltolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported

 

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester It is generally safe for use in children, with adjustments in dosing for those under 20 kg Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin

 

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action The timing and severity of the missed dose will be considered to determine the most suitable response

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Related Faqs

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How does Malicure work?

The mechanism of action involves the generation of highly reactive free radicals that are responsible for eradicating the malarial parasite known as Plasmodium These free radicals are formed and released by the medication targeting the parasites essential structures and components The destructive nature of these radicals disrupts the functioning of the parasites crucial processes leading to its ultimate demise By producing these potent free radicals the medication effectively neutralizes the Plasmodium parasite and prevents its ability to multiply and infect the hosts red blood cells This disruption of the parasites life cycle significantly reduces the severity and duration of the infection As a result the medication plays a vital role in treating and preventing the spread of malaria a lifethreatening disease caused by Plasmodium The production of free radicals is a unique characteristic of this medications mechanism of action The targeted attack on the parasites structures ensures minimal impact on the hosts own cells mitigating potential side effects This targeted approach allows for effective treatment while reducing the risk of harm to the patient In summary the medications effectiveness in combating malaria stems from its ability to generate free radicals that act specifically on the malarial parasite Plasmodium By disrupting the parasites essential processes the medication plays a crucial role in eradicating the infection and preventing its spread providing relief to individuals affected by this perilous disease

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Where does Malicure come from?

Artemisinin a valuable compound used in the treatment of malaria is extracted from the Artemisinin tree This natural herb has been extensively cultivated for its medicinal properties particularly in regions where malaria is prevalent The process of obtaining Artemisinin involves extracting the compound from the leaves and stems of the tree Artemisinin has gained worldwide recognition for its potent antimalarial effects When administered it effectively targets and kills the malaria parasites present in the bloodstream providing relief to infected individuals The success of Artemisininbased therapies is attributed to the compounds unique mechanism of action which interferes with the parasites ability to replicate and survive The Artemisinin tree scientifically known as Artemisia annua is native to certain regions in Asia including China and Vietnam However due to its increasing demand the cultivation of this tree has expanded to other parts of the world as well Extensive research has been conducted to improve the production and availability of Artemisinin resulting in the development of various strategies to increase its yield The discovery and utilization of Artemisinin have brought significant advancements in malaria treatment contributing to the global efforts in eradicating this deadly disease Additionally its natural origin and relatively low toxicity make it a favorable choice for pharmaceutical purposes The sustained cultivation and extraction of Artemisinin from the Artemisinin tree continue to play a crucial role in combating malaria and saving countless lives worldwide

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Is Malicure banned in India?

No the medication is only available in India with a valid prescription from a doctor Obtaining medication without a prescription is not permitted and is considered illegal It is important to follow the proper channels and consult with a healthcare professional to ensure the safe and appropriate use of medications In India strict regulations are in place to regulate the distribution and sale of prescription drugs in order to protect public health and prevent misuse or abuse These regulations aim to ensure that individuals receive the correct medication for their specific needs and that they are under the supervision and guidance of a qualified healthcare provider Therefore it is crucial to prioritize ones health and seek professional medical advice before considering any type of medication By doing so individuals can receive the necessary guidance and attention to ensure their wellbeing and prevent any potential adverse effects that may result from selfmedication or unauthorized access to prescription drugs

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How does Falno work?

The mechanism of action involves the generation of free radicals which effectively eradicates the malarial parasite known as Plasmodium This process plays a crucial role in combating the harmful effects of malaria By producing these highly reactive molecules the medication targets the parasite and disrupts its vital functions leading to its eventual demise These free radicals possess a remarkable ability to destroy the intricate structure of the Plasmodium parasite effectively neutralizing its growth and reproduction This innovative mode of action ensures the elimination of the parasite thereby alleviating the symptoms of malaria and preventing its further progression The selective action of this medication on the malarial parasite guarantees a targeted approach maximizing the efficacy of treatment and minimizing potential side effects Ultimately through the generation of free radicals this drug demonstrates its effectiveness in eradicating the Plasmodium parasite offering hope to those afflicted with malaria and contributing to the global efforts in combating this widespread and devastating disease

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How does Maxinate work?

The mechanism of action of this substance involves the generation of free radicals which effectively exterminate the Plasmodium parasite responsible for causing malaria By producing these highly reactive particles this substance exhibits a potent antimalarial effect The free radicals generated upon administration of this substance target the vital structures and metabolic processes of the malarial parasite leading to its eradication By disrupting the parasites normal functioning this substance effectively halts the progression of the disease and promotes the elimination of the infection This unique mechanism of action sets this substance apart as an efficient and effective option in the fight against malaria Its ability to specifically target and eliminate the Plasmodium parasite showcases its potential to combat this widespread and lifethreatening disease By harnessing the power of free radicals this substance offers a promising strategy for inhibiting the growth and survival of the malarial parasite ultimately contributing to the global efforts to control and eliminate malaria

Written By:

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Published At: Oct 19, 2023

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Oct 19, 2023

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.