Ofrel 100mg Tablet (OFLOXACIN)
What is Ofrel tablet?
Ofrel tablet is an antibiotic used to treat infections like pneumonia, skin infections, and urinary tract infections. It belongs to the fluoroquinolone class and works by killing bacteria that cause infections. It inhibits bacterial enzymes necessary for DNA replication, effectively stopping bacterial growth.
What is the usual dose of Ofrel tablet?
For adults, the usual dose of Ofrel tablet is 200 mg to 400 mg taken orally every 12 hours. The dosage for children is not established as Ofrel tablet is not recommended for individuals under 18 years of age due to potential side effects on bone and joint development.
How do I take Ofrel tablet?
Ofrel tablet can be taken with or without food, usually twice a day. It should be taken at the same times each day, spaced 12 hours apart. Avoid taking it within 2 hours of antacids, sucralfate, or supplements containing calcium, magnesium, aluminum, iron, or zinc to ensure proper absorption.
For how long do I take Ofrel tablet?
The typical duration of use for Ofrel tablet varies depending on the type and severity of the infection. It is usually taken for 3 days to 6 weeks. Your doctor will determine the exact length of treatment based on your specific condition.
What is Ofrel tablet used for?
Ofrel tablet is indicated for treating infections such as pneumonia, skin infections, bladder infections, reproductive organ infections, and prostate infections. It may also be used for bronchitis, urinary tract infections, and certain sexually transmitted diseases when other treatments are not available.
How long does it take for Ofrel tablet to start working?
You should begin to feel better during the first few days of treatment with Ofrel tablet. If your symptoms do not improve or worsen, contact your doctor for further evaluation.
Is Ofrel tablet effective?
Ofrel tablet is a fluoroquinolone antibiotic effective against a wide range of gram-negative and gram-positive bacteria. It works by inhibiting bacterial enzymes necessary for DNA replication. Clinical studies have shown its effectiveness in treating infections like pneumonia, skin infections, and urinary tract infections.
How does one know if Ofrel tablet is working?
The benefit of Ofrel tablet is evaluated through clinical improvement in symptoms and laboratory tests to check the body's response. Regular follow-ups with your doctor and laboratory tests may be necessary to ensure the medication is working effectively.
How does Ofrel tablet work?
Ofrel tablet works by inhibiting bacterial enzymes, specifically DNA gyrase and topoisomerase IV, which are necessary for DNA replication, transcription, repair, and recombination. This action effectively stops bacterial growth and kills the bacteria causing the infection.
Who should avoid taking Ofrel tablet?
Important warnings for Ofrel tablet include the risk of tendinitis and tendon rupture, peripheral neuropathy, and central nervous system effects. It is contraindicated in patients with a history of hypersensitivity to quinolones, epilepsy, or tendon disorders. Patients should avoid excessive sunlight exposure and inform their doctor of any history of heart, kidney, or liver issues.
Can I take Ofrel tablet with vitamins or supplements?
Ofrel tablet can interact with supplements containing calcium, magnesium, aluminum, iron, or zinc, which can reduce its absorption. It is recommended to take Ofrel tablet at least 2 hours before or after these supplements to avoid interactions.
Can I take Ofrel tablet with other prescription drugs?
Ofrel tablet can interact with antacids, sucralfate, and multivitamins containing iron or zinc, reducing its absorption. It may also interact with non-steroidal anti-inflammatory drugs, increasing the risk of CNS stimulation. Patients should inform their doctor of all medications they are taking to avoid potential interactions.
Can Ofrel tablet be taken safely while pregnant?
Ofrel tablet is not recommended during pregnancy due to potential harm to the fetus, as animal studies have shown damage to joint cartilage in immature animals. There is limited human data, so it should only be used if the potential benefit justifies the risk to the fetus.
Can Ofrel tablet be taken safely while breastfeeding?
Ofrel tablet passes into breast milk and may cause serious adverse reactions in nursing infants. It is recommended to either discontinue breastfeeding or the medication, considering the importance of the drug to the mother.
Is Ofrel tablet safe for the elderly?
Elderly patients are at increased risk for severe tendon disorders, including tendon rupture, when taking Ofrel tablet. This risk is higher for those on corticosteroids. Dosage adjustments may be necessary for elderly patients with impaired renal function. Elderly patients should be informed of these risks and advised to contact their healthcare provider if symptoms occur.
How should I store Ofrel tablet?
Store Ofrel tablet in its original container, tightly closed, at room temperature away from excess heat and moisture. Keep it out of reach of children. Do not store it in the bathroom. Dispose of unneeded medication through a take-back program.
Does Ofrel tablet make people tired or drowsy?
Commonly reported constitutional side effects of Ofrel tablet include excessive tiredness. If you experience severe or persistent tiredness, it is important to contact your doctor. They may adjust your dosage or suggest an alternative treatment.
Does Ofrel tablet cause stomach upset?
Common gastrointestinal side effects of Ofrel tablet include nausea (10%), diarrhea (4%), vomiting (4%), and abdominal pain. If these symptoms are severe or persistent, contact your doctor. They may adjust your treatment or suggest ways to manage the side effects.
Does Ofrel tablet affect sleep?
Insomnia is a reported side effect of Ofrel tablet, occurring in about 3% of patients. If you experience difficulty sleeping, consult your doctor. They may recommend adjusting your dosage or switching to a different medication.
Does Ofrel tablet make it hard to think or concentrate?
Cognitive side effects of Ofrel tablet, such as confusion and memory problems, are rare but serious. If you experience these symptoms, stop taking the medication and contact your doctor immediately. They may need to adjust your treatment plan.
Does Ofrel tablet affect mood?
Mental health side effects of Ofrel tablet can include anxiety, depression, and confusion. These effects are rare but serious. If you experience any changes in mood or behavior, stop taking the medication and contact your doctor immediately for advice.
Does Ofrel tablet affect appetite?
Ofrel tablet may cause a change in appetite, including loss of appetite. If you experience a significant change in your eating habits, consult your doctor. They may adjust your dosage or suggest dietary adjustments to manage the side effect.
Does Ofrel tablet cause weight gain?
Weight loss is a less common side effect of Ofrel tablet. If you notice significant weight changes, consult your doctor. They may evaluate your condition and adjust your treatment plan if necessary.
Does Ofrel tablet cause headaches?
Headaches are a common side effect of Ofrel tablet, occurring in about 9% of patients. If you experience persistent or severe headaches, contact your doctor. They may recommend an over-the-counter pain reliever or adjust your medication.
Does Ofrel tablet limit driving?
Ofrel tablet can cause dizziness and lightheadedness, which may impair your ability to drive or operate machinery. Until you know how Ofrel tablet affects you, avoid driving or engaging in activities that require full alertness and coordination.
Is it safe to exercise while taking Ofrel tablet?
Ofrel tablet may limit the ability to exercise due to its potential to cause tendinitis or tendon rupture, especially in the Achilles tendon. If you experience pain, swelling, or inflammation in a tendon, stop exercising and consult your doctor immediately.
What are Ofrel tablet possible harms and risks?
Common side effects of Ofrel tablet include nausea (10%), headache (9%), insomnia (7%), dizziness (5%), and diarrhea (4%). Serious adverse effects can include tendon rupture, peripheral neuropathy, and central nervous system effects. If you experience any severe side effects, contact your doctor immediately.
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