mifiact (MIFEPRISTONE)

What is Mifiact?
Mifiact is a medication used primarily for medical abortion in early pregnancy and for treating Cushing’s syndrome. It works by blocking progesterone, a hormone needed to maintain pregnancy, leading to the detachment of the pregnancy from the uterus. It is often used with misoprostol to complete the abortion process. In Cushing’s syndrome, it helps reduce high blood sugar by blocking cortisol effects. It is a prescription drug and should be taken under medical supervision.

What is the usual dose of Mifiact?
For medical abortion, the typical dose is 200 mg taken once, followed by misoprostol (800 mcg) after 24–48 hours. For Cushing’s syndrome, the dose starts at 300 mg per day and may be increased based on response. The dosage may vary depending on the individual’s health condition and should be prescribed by a doctor to ensure safety and effectiveness.

How do I take Mifiact?
Mifiact should be taken orally with water. For abortion, it is followed by misoprostol, which helps expel the pregnancy. It is best taken under medical supervision to monitor any complications. Do not take it with grapefruit juice, as it may interfere with absorption. Always follow your doctor’s instructions for the best results and safety.

For how long do I take Mifiact?
For medical abortion, it is taken as a single dose, followed by misoprostol after 24–48 hours. For Cushing’s syndrome, it is taken daily for long-term management, depending on the patient's response and doctor’s guidance. The duration varies based on the condition being treated, and medical follow-up is necessary to assess effectiveness and any side effects.

What is Mifiact used for?
Mifiact is primarily used for medical abortion in pregnancies up to 10 weeks. It is also used to treat Cushing’s syndrome in patients with high blood sugar levels due to excess cortisol. Additionally, it may be used in certain cases of missed miscarriage and as an investigational drug for other hormonal conditions.

How long does it take for Mifiact to start working?
For abortion, Mifiact starts working within 24 to 48 hours, causing the pregnancy to detach from the uterus. Misoprostol, taken afterward, induces uterine contractions to expel the pregnancy. For Cushing’s syndrome, the effects may take several weeks to regulate blood sugar and cortisol levels.

Is Mifiact effective?
Yes, Mifiact is highly effective for medical abortion, with a success rate of 95-98% when combined with misoprostol. It is also effective in treating Cushing’s syndrome, helping control blood sugar and cortisol levels. However, its effectiveness depends on correct usage and medical supervision.

How does one know if Mifiact is working?
For abortion, signs include bleeding and cramping within 24–48 hours after taking misoprostol. A follow-up test or ultrasound after 7–14 days confirms success. In Cushing’s syndrome, improvement in blood sugar levels and symptoms indicates effectiveness. If no changes occur, consult a doctor for further evaluation.

How does Mifiact work?
Mifiact works by blocking progesterone, a hormone needed for pregnancy. This causes the uterine lining to break down, making it unsuitable for pregnancy. In Cushing’s syndrome, it blocks cortisol receptors, helping reduce high blood sugar levels. Its action depends on the condition being treated.

Who should avoid taking Mifiact?
Women with ectopic pregnancy, bleeding disorders, severe anemia, or adrenal insufficiency should avoid it. It is also not recommended for those with liver disease, kidney problems, or heart conditions. Always consult a doctor before taking Mifiact to ensure it is safe based on your health condition.

Can I take Mifiact with vitamins or supplements?
Some vitamins and supplements, like St. John’s Wort, may reduce its effectiveness. Avoid grapefruit juice and high-dose vitamin C, as they can interfere with absorption. Always check with your doctor before taking supplements with Mifiact.

Can I take Mifiact with other prescription drugs?
Mifiact interacts with anticoagulants, corticosteroids, antifungal drugs, and certain antibiotics, affecting its function. If you take other medications, consult a doctor to avoid harmful interactions. It is essential to disclose all medicines before starting treatment.

Can Mifiact be taken safely while pregnant?
No, Mifiact is used to terminate pregnancy and should not be taken by women wanting to continue pregnancy. If mistakenly taken, seek immediate medical help to assess the situation and possible complications.

Can Mifiact be taken safely while breastfeeding?
Mifiact may pass into breast milk, but its effects on infants are unclear. It is advised to pump and discard breast milk for a few days after taking it. Consult a doctor before using it while breastfeeding.

Is Mifiact safe for the elderly?
Mifiact is not commonly used in elderly patients except for Cushing’s syndrome. If prescribed, close monitoring is needed for liver function, blood sugar, and potential side effects. Always consult a doctor before use.

How should I store Mifiact?
Store at room temperature (20–25°C) in a dry place, away from light and moisture. Keep it out of reach of children. Do not use expired medication, as it may lose effectiveness.

Does Mifiact make people tired or drowsy?
Some people may experience fatigue or dizziness after taking Mifiact. If this happens, rest and avoid activities requiring alertness, like driving, until the symptoms go away.

Does Mifiact cause stomach upset?
Yes, nausea, vomiting, and diarrhea are common side effects. Taking it with water and resting can help. If symptoms are severe, consult a doctor for medical advice.

Does Mifiact affect sleep?
Some people experience insomnia or disrupted sleep after taking Mifiact. If this occurs, maintain a relaxing bedtime routine and avoid caffeine. If severe, consult a doctor.

Does Mifiact make it hard to think or concentrate?
In rare cases, Mifiact may cause dizziness or confusion. If this affects daily activities, avoid driving or operating machinery and seek medical advice if symptoms persist.

Does Mifiact affect mood?
Some users report anxiety, mood swings, or irritability after taking Mifiact. These effects are usually temporary. If mood changes are severe or persistent, consult a healthcare provider.

Does Mifiact interfere with sexual function?
Mifiact is not known to directly affect libido or sexual performance, but its emotional and physical effects may temporarily reduce interest in sexual activity.

Does Mifiact affect appetite?
Some users may experience loss of appetite, while others report increased hunger due to hormonal changes. Eating balanced meals and staying hydrated can help manage these effects.

Does Mifiact cause weight gain?
Weight changes are not common, but some people may experience fluid retention or bloating. If significant weight gain occurs, consult a doctor for advice.

Does Mifiact cause headaches?
Yes, mild to moderate headaches are a possible side effect. Staying hydrated and resting may help. If severe, seek medical advice.

Does Mifiact limit driving?
Mifiact may cause dizziness, lightheadedness, tiredness, weakness, and nausea. This can make it difficult to drive or do other tasks that require your full attention. Talk to your doctor about whether it is safe for you to drive or do other activities while taking this medication.

Is it safe to drink alcohol while taking Mifiact?
Alcohol may increase dizziness, nausea, and liver strain. It is best to avoid alcohol while taking Mifiact.

Is it safe to drink coffee or tea while taking Mifiact?
Caffeine does not interact directly but may worsen nausea or anxiety. If sensitive, limit intake while taking Mifiact.

Is it safe to exercise while taking Mifiact?
Light activity is fine, but avoid heavy exercise if you feel weak, dizzy, or have heavy bleeding. Listen to your body and rest if needed.

What are Mifiact possible harms and risks?
Common side effects include nausea, vomiting, cramping, diarrhea, headache, and dizziness. Serious risks include excessive bleeding, infection, and incomplete abortion, requiring medical attention. In rare cases, severe allergic reactions can occur. Monitoring and follow-up with a doctor help manage these risks effectively.
Available in 2 variations

Mifiact 25mg Tablet 10s
Mifepristone (25mg)
strip of 10 tablets

Mifiact 10mg Tablet
Mifepristone (10mg)
strip of 10 tablets