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Martinate 60mg Injection

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Introduction to Martinate 60mg Injection

Martinate 60mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well-tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

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How Martinate 60mg Injection Works

Artesunate transforms into an active form, DHA, which acts like a superhero. It engages with heme, producing free radicals that disrupt the growth of malaria parasites in red blood cells. This strategic attack weakens the parasites at every stage, preventing their growth and ultimately defeating them in the battle against malaria. It's like a superhero breaking down the enemy's defenses and ensuring they can't multiply, protecting the body from malaria.

How to take Martinate 60mg Injection

This medicine will be provided by your doctor or nurse; please avoid selfadministration
Do not take it on your own; wait for guidance from your doctor or nurse
Trust your healthcare professional to administer the medicine; do not attempt selfadministration

Special Precautions about Martinate 60mg Injection

Artesunate is primarily used for the treatment of severe malaria, especially caused by Plasmodium falciparum. It is not typically used for uncomplicated malaria. The diagnosis of severe malaria must be confirmed before initiating treatment with Artesunate.
Regular monitoring of liver function is recommended during Artesunate treatment, especially in patients with preexisting liver conditions. Elevated liver enzymes may occur, and dose adjustments or discontinuation may be necessary.

USES IN Martinate 60mg Injection

Malaria

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For information purposes only. Consult a doctor before taking any medicines.

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Drug Interaction :

Consult a healthcare provider for an accurate interpretation of interactions with Artesunate; seek immediate help if experiencing adverse effects.
Note that the absence of interaction does not guarantee any interactions.
Exercise caution with drugs like Acetophenazine, Alimemazine, and Artemether, which may increase QTc prolongation.
Ambroxol can elevate the risk of methemoglobinemia when combined with Artesunate.
Stay vigilant with Articaine, as its combination with Artesunate may also heighten the risk of methemoglobinemia.

Drug-Food Interaction

No interactions were identified between Artesunate and food; consult a healthcare provider for accurate information and potential drug-related concerns.
Consult your healthcare provider for more information.

Habit Forming

No

Disease Explanation :

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Written By:

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Published At: Oct 19, 2023

Updated At: May 10, 2024

Reviewed By:

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Published At: Oct 19, 2023

Updated At: May 10, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

Martinate 60mg Injection

Prescription Required

Packaging :

vial of 1 Injection

Composition :

Artesunate (60mg)

MRP :

₹191₹212
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100% genuine medicines

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Safe and secure payments

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90 days Easy returns