losaline (LOSARTAN)
Introduction to Losaline
Losaline is a medication primarily used to manage and treat conditions related to the heart and blood vessels. It is particularly effective in treating high blood pressure, hea... See More

What is Losaline?
Losaline is an angiotensin II receptor blocker (ARB) commonly used to treat high blood pressure (hypertension) and heart failure. It is also prescribed to protect the kidneys in diabetic nephropathy. Losaline works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thus helping to relax and widen blood vessels, lowering blood pressure and improving heart function.

How do I take Losaline?
Losaline can be taken with or without food. There are no specific food restrictions, but avoid high-potassium foods or supplements as Losaline can increase potassium levels. Take once daily, at the same time each day. Swallow the tablet whole, without crushing or chewing. Follow your doctor’s advice on potassium intake and other medications you may be taking.

For how long do I take Losaline?
Losaline is often a medicine you take for a long time, maybe even your whole life.

What is Losaline used for?
Losaline is indicated for treating hypertension (high blood pressure), heart failure, and diabetic nephropathy (kidney disease in diabetes). It’s also used to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy (enlarged heart). Losaline helps lower blood pressure and protect kidney function, improving overall cardiovascular health.

How long does it take for Losaline to start working?
Your blood pressure may go down in the first week of taking Losaline, but it may take up to 6 weeks to feel the full effects.

Is Losaline effective?
Evidence supporting Losaline’s effectiveness comes from clinical trials showing it significantly reduces blood pressure, improving cardiovascular outcomes. Studies like the Losaline Heart Failure Study demonstrated its ability to reduce symptoms and hospitalizations in heart failure patients. It also effectively protects kidney function in those with diabetic nephropathy and reduces the risk of stroke in high-risk patients.

How does one know if Losaline is working?
The benefit of Losaline is evaluated by regularly monitoring blood pressure to ensure it stays within the target range. In patients with heart failure or diabetic nephropathy, kidney function and creatinine levels are also monitored. Additionally, doctors may assess heart function and symptoms to determine if the medication is effectively improving overall cardiovascular health and reducing risks.

How does Losaline work?
Losaline works by blocking the action of angiotensin II, a hormone that constricts blood vessels and raises blood pressure. By blocking angiotensin II receptors, Losaline helps relax and widen blood vessels, which lowers blood pressure. This action improves heart function, reduces strain on the heart, and helps protect the kidneys, particularly in people with diabetes.

Who should avoid taking Losaline?
Losaline is contraindicated in pregnancy, particularly in the second and third trimesters, due to risks to the fetus. It should not be used in patients with severe liver impairment or allergy to the drug. Caution is advised for those with kidney problems, low blood pressure, or high potassium levels. Regular monitoring of blood pressure, kidney function, and potassium is important.

Can I take Losaline with vitamins or supplements?
Significant interactions with Losaline include potassium supplements or high-potassium foods (e.g., bananas, spinach), which can increase the risk of hyperkalemia (high potassium levels). Vitamin D and calcium supplements may also affect Losaline's effectiveness. It’s important to consult a healthcare provider before taking any vitamins or supplements to avoid interactions that could impact blood pressure or kidney function.

Can I take Losaline with other prescription drugs?
Significant interactions with Losaline include diuretics (e.g., spironolactone) which may increase the risk of low blood pressure or kidney problems. ACE inhibitors (e.g., enalapril) or renin inhibitors (e.g., aliskiren) can cause hyperkalemia and kidney issues. NSAIDs (e.g., ibuprofen) may reduce Losaline’s effectiveness and harm kidney function. Always consult your doctor about all medications you're taking.

Can Losaline be taken safely while pregnant?
Losaline is a medication that should not be taken by pregnant women. If taken during pregnancy, it can decrease the amount of fluid surrounding the developing baby, especially in the second and third trimesters. This can cause harm to the baby's kidneys and lungs, leading to long-term health issues. If you discover you are pregnant while taking Losaline, stop taking it and consult your doctor immediately.

Can Losaline be taken safely while breastfeeding?
It's usually okay to breastfeed while taking Losaline, but it's important to talk to your doctor first. However, if your baby was born prematurely, it's best to avoid taking Losaline. Your doctor can help you decide the best course of action.

Is Losaline safe for the elderly?
Losaline is a medicine for high blood pressure and kidney protection in people with type 2 diabetes. In studies, a smaller percentage of older people (65 and older) took part in the high blood pressure trials compared to the diabetes trials. Doctors found Losaline worked similarly well in both younger and older adults, but some older people might be more sensitive to it. It's important for doctors to check potassium levels in the blood regularly, and they may need to adjust the dose or stop the medicine if necessary.

How should I store Losaline?
To keep your Losaline medicine in good condition, store it properly. Put it in a container that closes tightly to keep out light. The temperature should stay between 59°F to 86°F (15°C to 30°C). Most importantly, keep it and all other medicines out of reach of children for safety.

Does Losaline make people tired or drowsy?
Yes, Losaline can cause dizziness, which was reported in 3% of patients in clinical trials. If you experience dizziness or lightheadedness, especially after getting up from a lying or sitting position, get up slowly and talk to your doctor.

Does Losaline cause stomach upset?
Yes, Losaline can cause stomach upset like abdominal pain, nausea, vomiting, and diarrhea. These side effects were reported in less than 2% of patients. If you experience gastrointestinal issues, consult your doctor for advice on managing these side effects.

Does Losaline affect sleep?
Losaline can cause sleep disorders. If you experience a change in sleep, talk to your doctor to see if they recommend any changes to your medication or sleep habits.

Does Losaline make it hard to think or concentrate?
Yes, Losaline may affect your ability to think or concentrate. Side effects like somnolence and headache can cause problems with concentration, attention, and memory. If you experience these side effects, talk to your doctor.

Does Losaline affect mood?
Yes, Losaline can affect your mood. It may cause depression. If you experience mood swings, depression, or anxiety while taking this medication, it is important to consult your doctor for further evaluation and guidance.

Does Losaline interfere with sexual function?
Yes, Losaline can cause impotence. If you experience sexual side effects while taking Losaline, talk to your doctor as they may be able to adjust your dose or suggest alternative treatments.

Does Losaline affect appetite?
There is no enough data to prove that Losaline affects appetite.

Does Losaline cause weight gain?
Weight gain is not a commonly reported side effect of Losaline. In fact, it is more likely to cause weight loss in rare cases due to its potential impact on fluid retention and blood pressure.

Does Losaline cause headaches?
Losaline can cause headaches. If you experience headaches while taking Losaline, talk to your doctor to see if they recommend any changes to your medication or over-the-counter pain relief.

Does Losaline limit driving?
Losaline can cause dizziness. If you experience dizziness, do not drive or operate machinery.

Is it safe to drink alcohol while taking Losaline?
Alcohol can lower blood pressure, which might amplify Losaline's effects and cause dizziness or fainting. It's best to limit alcohol intake and consult your doctor for personalized advice.

Is it safe to drink coffee or tea while taking Losaline?
Moderate consumption of coffee or tea is generally safe, but caffeine can sometimes raise blood pressure slightly. If you're concerned, talk to your doctor or pharmacist.

Is it safe to exercise while taking Losaline?
Regular exercise is beneficial, but since Losaline lowers blood pressure, you may feel dizzy during activity. Speak to your doctor before starting a new or intense exercise routine to ensure safety.

What are Losaline possible harms and risks?
Common side effects of Losaline include dizziness, headache, fatigue, and nasal congestion. Significant adverse effects may include low blood pressure (hypotension), elevated potassium levels (hyperkalemia), and kidney problems. In rare cases, it can cause angioedema (swelling of deeper layers of skin). Serious side effects require immediate medical attention.
Available in 2 variations

Losaline 50mg Tablet
Losaline 50mg Tablet
Losartan (50mg)
strip of 10 tablets

Losaline 25mg Tablet
Losaline 25mg Tablet
Losartan (25mg)
strip of 10 tablets