Kenther 150mg Injection

Liver and Spleen Damage from Dengue: Pathogenesis

What are some common preventive measures that individuals can take to reduce the risk of dengue virus infection?

• Dengue virus, transmitted by mosquitoes, enters the human body through infected mosquito bites.

• The virus primarily infects white blood cells, specifically monocytes and macrophages, crucial for the immune response.

• Infected cells spread the virus to various body parts, including the liver and spleen.

• The liver filters blood and eliminates toxins, while the spleen filters blood and removes old or damaged red blood cells.

• Dengue virus causes inflammation and damage to liver and spleen cells, triggering an immune response.

• Immune cells release cytokines and chemokines, attracting more immune cells and causing further organ damage.

• Symptoms of liver and spleen damage include abdominal pain, nausea, vomiting, and jaundice.

• Severe cases may lead to liver failure and bleeding disorders.

• Preventive measures, such as using mosquito repellent and wearing protective clothing, are crucial to avoid dengue virus infection.

Disclaimer:- This information is intended to supplement, not substitute, advice from your healthcare provider or doctor. It does not cover all possible uses, precautions, interactions, or side effects, and may not be appropriate for your specific healthcare needs. Always consult with your doctor or another qualified healthcare provider before modifying or discontinuing any prescribed portion of your healthcare plan or treatment, in order to determine the best course of therapy for you. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki. 

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New Discovery May Lead To a Cure For Deadly Malaria Parasite

How did the study on long noncoding ribonucleic acids (lncRNAs) in Plasmodium falciparum contribute to understanding the parasite's life cycle, sexual differentiation for malaria?

These follow are :-

Malaria Statistics (2020):

• Clinical Cases: 241 million
• Deaths: 627,000
• Key Culprit: Plasmodium falciparum
• Vulnerable Groups: Pregnant women and young children in endemic areas

Research Focus:

• Objective: Understand gene expression regulation in P. falciparum lifecycle.
• Investigative Molecule: Long noncoding RNAs (lncRNAs)
• Connection to Diseases: LncRNAs associated with neurological disorders and cancer.

Specific Study on P. falciparum LncRNAs:

• Targeted Aspect: Regulation of sex determination and sexual differentiation.
• Localization Impact: LncRNAs found in different cellular compartments.
• Total LncRNAs Identified: 1,768
  • New Discoveries: 718 previously unknown lncRNAs.
• Role Significance: Novel lncRNAs crucial for parasite lifecycle progression.

Implications of Findings:

• Insights Gained: Understand P. falciparum lifecycle, sexual differentiation, and gene regulation.
• Therapeutic Potential: Targeted strategies against P. falciparum envisioned.
• Goals:
  1. Halt Lifecycle Progression.
  2. Block Transmission to Mosquitoes.
  3. Prevent Malaria Spread.

Researcher Outlook:

• Hopeful Impact: Novel insights contributing to the development of antimalarial therapies.
• Long-term Goal: Combat malaria by disrupting the parasite's lifecycle and transmission pathways.

Sources:https://www.sciencedaily.com/releases/2023/08/230828162349.htm 

Disclaimer:-This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki. 

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The Deadly Bite of Mosquitoes in Spreading Malaria.

What are some ways to prevent and control malaria, and why is community education important in reducing its transmission?

These follow are :-

Malaria Statistics:

• World Malaria Report 2021: 247 million cases (up from 245 million in 2020), with deaths decreasing from 625,000 to 619,000.
• In 2019, India reported approximately 5.6 million malaria cases, making it a significant public health concern.

Malaria Transmission:

• Life-threatening disease transmitted through bites of infected female Anopheles mosquitoes.

Transmission Routes:

• Mosquitoes pick up Plasmodium parasites by biting an infected person and transmit them when biting another person.
• Can also be transmitted through blood transfusions, sharing of contaminated needles, or from mother to unborn child during pregnancy.

Infection Stages:

• Liver stage: Parasites enter the liver and multiply, often without causing symptoms.
• Blood stage: Parasites infect red blood cells, causing symptoms like fever, chills, headache, and fatigue.

Severe Cases and Complications:

• Malaria can lead to organ failure, seizures, coma, and is fatal if untreated.

Prevention and Control:

• Strategies include bed nets treated with insecticides, indoor spraying, early diagnosis, and treatment.
• Community education and awareness are crucial to reduce transmission rates.

Global Collaboration:

• Joint efforts can lead to the eradication of malaria, contributing to improved global health.

Disclaimer:- This information is intended to supplement, not substitute, advice from your healthcare provider or doctor. It does not cover all possible uses, precautions, interactions, or side effects, and may not be appropriate for your specific healthcare needs. Always consult with your doctor or another qualified healthcare provider before modifying or discontinuing any prescribed portion of your healthcare plan or treatment, in order to determine the best course of therapy for you. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki. 

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Top Home Remedies to Cure and Prevent Malaria Naturally

What are some simple ways to prevent and manage malaria, especially in terms of avoiding mosquito bites and using natural remedies?

These ways are:-

Avoid Mosquito Bites:

• Use mosquito repellent.
• Wear long-sleeved clothing.
• Sleep under insecticide-treated bed nets to prevent mosquito bites.

Natural Remedies in India:

• Neem juice and neem leaves have anti-malarial properties.
• Papaya leaves can boost the immune system and reduce malaria symptoms.

Stay Hydrated:

• Malaria can cause dehydration.
• Drink water, coconut water, or electrolyte-rich fluids.

Over-the-Counter Pain Relievers:

• Acetaminophen or ibuprofen can reduce fever and relieve pain.

Get Plenty of Rest:

• Rest is crucial for the body to recover from malaria.
• Helps the body fight the malaria parasite and reduces symptom severity.

Medical Treatment Reminder:

• Home remedies can alleviate symptoms but seek medical treatment for suspected malaria.
• Doctors can prescribe medications to cure the disease and prevent complications.

Disclaimer:- This information is intended to supplement, not substitute, advice from your healthcare provider or doctor. It does not cover all possible uses, precautions, interactions, or side effects, and may not be appropriate for your specific healthcare needs. Always consult with your doctor or another qualified healthcare provider before modifying or discontinuing any prescribed portion of your healthcare plan or treatment, in order to determine the best course of therapy for you. Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki. 

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Malaria Cause, Signs, Transmission, Treatment and Prevention

Understanding Malaria: Symptoms, Transmission, and Risks

Malaria, a life-threatening disease transmitted by infected Anopheles mosquitoes. Symptoms range from mild to severe, including fever, chills, and confusion. Transmission can also occur through blood transfusion or contaminated needles. 

Diagnosis and Tests: 

• - Parasite-based testing confirms malaria, with blood tests identifying the parasite type, drug resistance, and organ impact. 
• - Quick blood tests yield results in under 15 minutes, facilitating prompt treatment initiation. 

Treatment: 

• - Treatment varies based on parasite type, symptom severity, age, and pregnancy status. Antimalarial drugs like chloroquine, quinine sulfate, and artemisinin-based combinations are common. 

Prevention: 

• - Preventive measures include insect repellents, bed nets, and antimalarial medications. 
• - Vaccines like RTS,S/AS01 and R21/Matrix-M are recommended in high transmission areas by WHO. 

Watch our next video to know about Life Cycle of Malaria! 

Source:-Fact sheet about malaria. (2024, March 1). Fact sheet about malaria. https://www.who.int/news-room/fact-sheets/detail/malaria 
 

Disclaimer:-This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment.Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

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