Dothiwel 25mg Tablet

Introduction to Dothiwel 25mg Tablet

Dothiwel 25mg Tablet belongs to the class of medications known as tricyclic antidepressants used primarily in the treatment of depression. This medication operates by elevating the levels of noradrenaline and serotonin in the brain. By impeding their reuptake, it amplifies their effects within the brain's synaptic cleft Dosulepin's multifaceted mechanism also involves interaction with specific receptors, such as α2adrenoceptors and serotonin receptors, contributing to its antidepressant effects. Additionally, it affects histamine receptors, inducing sedation, and can lead to dry mouth through its action on muscarinic acetylcholine receptors.

It functions by inhibiting the reuptake of noradrenaline and serotonin, crucial neurotransmitters associated with mood regulation. By doing so, it heightens their levels in the brain, fostering an improved mood and relieving symptoms of depression. Its interaction with various receptors further augments its antidepressant effects through multiple neurochemical pathways.

Adherence to your doctor's instructions regarding it is vital. It can be taken with or without food, but maintaining a consistent daily schedule is advisable for optimal results.

Some common side effects associated with this include dryness in the mouth, difficulty in urination, constipation, dizziness, sedation, and loss of accommodation.

Tricyclic antidepressants it can affect the heart's conduction system, potentially leading to arrhythmias Individuals with a history of heart problems, recent myocardial infarction, heart block, or arrhythmias should inform their healthcare provider. Regular monitoring of cardiac function may be necessary.

It might increase intraocular pressure, which could worsen symptoms in individuals with glaucoma. Regular eye checkups are advisable for those with glaucoma.

If a dose of this drug is missed, it should be taken as soon as remembered. However, if the next dose is approaching, it's advised to skip the missed dose and continue with the regular dosing schedule. Avoid taking double doses to compensate for the missed one and consult your doctor for guidance on managing missed doses effectively.


How Dothiwel 25mg Tablet Works

Dosulepin increases the levels of noradrenaline and serotonin in the brain by blocking their reuptake, enhancing their effects in the synaptic cleft. It interacts with α2-adrenoceptors, promoting noradrenaline release for antidepressant effects. Dosulepin also binds to serotonin receptors, improving mood, and inhibits histamine receptors, causing sedation. The drug's metabolites exhibit similar actions. Additionally, dosulepin affects muscarinic acetylcholine receptors, leading to dry mouth. Overall, dosulepin's multi-target approach helps alleviate depression symptoms through various neurochemical mechanisms.

How to take Dothiwel 25mg Tablet

Follow your doctor's guidance for this medicine, taking it in the prescribed dose and duration
You can take this medicine with or without food, but maintaining a consistent time daily is recommended for better results
Swallow the drug whole; avoid chewing, crushing, or breaking it

Special Precautions about Dothiwel 25mg Tablet

Tricyclic antidepressants like do sulepin can affect the heart's conduction system, potentially leading to arrhythmias. If you have a history of heart problems, especially recent myocardial infarction, heart block, or arrhythmias, inform your healthcare provider. Regular monitoring of cardiac function may be necessary.
Tricyclic antidepressants may increase intraocular pressure, potentially worsening the symptoms of glaucoma. If you have glaucoma, regular eye checkups are advisable.
Dosulepin may lower the seizure threshold, increasing the risk of seizures. If you have a history of seizures or epilepsy, discuss this with your healthcare provider.

USES IN Dothiwel 25mg Tablet

Anxiety disorder

BENEFITS OF Dothiwel 25mg Tablet

It Relieves symptoms of depression.
It Supports mental wellbeing.
It Alleviates emotional distress.
Aids in managing depressive symptoms.

SIDE EFFECTS OF Dothiwel 25mg Tablet

Dryness in mouth
Difficulty in urination
Loss of accommodation

What if I Missed a Dose of Dothiwel 25mg Tablet

If you miss a dose, take it when you remember. If your next dose is close, skip the missed one and stay on your regular schedule. Avoid taking two doses at once. Consult your doctor for guidance on managing missed doses effectively.

Similar Medicines Of Dothiwel 25mg Tablet

For information purposes only. Consult a doctor before taking any medicines.

Dothiwel 25mg Tablet


Safety Advice For Dothiwel 25mg Tablet

Check for risk indication explain below.

High risk Moderate risk Safe

Disease Explanation :


Depression and anxiety are common mental health conditions that affect millions of pe ... Show More

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

Dothiwel 25mg Tablet

Prescription Required

Packaging :

strip of 10 tablets

Manufacturer :

Dellwich Healthcare LLP



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