Pregabalin
Postherpetic Neuralgia, Seizures ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
undefined
Controlled Drug Substance
YES
Pregabalin
Summary
Pregabalin is used to treat nerve pain, which is pain caused by damaged nerves, epilepsy, which is a condition causing seizures, and fibromyalgia, which is a condition causing widespread pain and fatigue.
Pregabalin works by calming overactive nerves, which helps reduce pain and seizures. It belongs to a class of drugs called anticonvulsants, which help stabilize electrical activity in the brain.
Pregabalin is usually taken by mouth in capsule form, once or twice daily. The starting dose for adults is typically 150 mg per day, which may be adjusted by a doctor up to a maximum of 600 mg per day.
Common side effects of Pregabalin include dizziness, which is a feeling of being unsteady, drowsiness, which is feeling sleepy, and dry mouth, which is a lack of saliva.
Pregabalin can cause dizziness and drowsiness, affecting your ability to drive. It may increase the risk of suicidal thoughts. Avoid alcohol, and inform your doctor of any allergies or medical history before use.
Indications and Purpose
How does Pregabalin work?
Pregabalin works by calming overactive nerves in the brain. It belongs to a class of drugs called anticonvulsants, which help reduce the release of certain chemicals that cause pain and seizures. Think of it like turning down the volume on a loud radio. By reducing nerve activity, Pregabalin helps relieve symptoms of nerve pain, epilepsy, and fibromyalgia, improving your quality of life.
Is Pregabalin effective?
Pregabalin is effective for treating conditions like nerve pain, epilepsy, and fibromyalgia, which is a condition causing widespread pain and fatigue. Clinical studies show Pregabalin reduces pain and improves sleep and quality of life for many users. It works by calming overactive nerves, which helps relieve symptoms. Always follow your doctor's instructions to achieve the best results with Pregabalin.
What is Pregabalin?
Pregabalin is a medication used to treat nerve pain, epilepsy, and fibromyalgia, which is a condition causing widespread pain and fatigue. It belongs to a class of drugs called anticonvulsants, which help calm overactive nerves. Pregabalin works by reducing the release of certain chemicals in the brain that cause pain and seizures. It's often used alongside other therapies to manage these conditions effectively.
Directions for Use
For how long do I take Pregabalin?
Pregabalin is usually taken long-term for chronic conditions like nerve pain or epilepsy. The duration of use depends on your condition and response to treatment. Your doctor will guide you on how long to take Pregabalin. Do not stop taking it without medical advice, as this could worsen your condition. Always follow your doctor's instructions for the best results.
How do I dispose of Pregabalin?
Dispose of unused Pregabalin by taking it to a drug take-back program or collection site at a pharmacy or hospital. If these options aren't available, you can throw it in the trash at home. First, mix the medication with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. This helps prevent harm to people and the environment.
How do I take Pregabalin?
Take Pregabalin exactly as your doctor prescribes. It's usually taken once or twice daily, with or without food. Swallow the capsule whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Avoid alcohol while taking Pregabalin, as it can increase side effects like dizziness. Always follow your doctor's specific instructions.
How long does it take for Pregabalin to start working?
Pregabalin starts working within a few days, but it may take several weeks to achieve its full effect. The time it takes to work can vary based on your condition and individual response. For nerve pain, you might notice relief within a week, while seizure control may take longer. Always take Pregabalin as prescribed and talk to your doctor if you have concerns about its effectiveness.
How should I store Pregabalin?
Store Pregabalin at room temperature, away from moisture and light. Keep it in a tightly closed container, out of reach of children and pets. Do not store it in the bathroom, where humidity can affect the medication. Check the expiration date regularly and dispose of any unused or expired Pregabalin properly, following your pharmacist's or local guidelines.
What is the usual dose of Pregabalin?
The usual starting dose of Pregabalin for adults is 150 mg per day, divided into two or three doses. Your doctor may adjust the dose based on your response and needs, up to a maximum of 600 mg per day. Pregabalin dosing may vary for different conditions and special populations like the elderly. Always follow your doctor's specific dosing instructions for your health needs.
Warnings and Precautions
Can I take Pregabalin with other prescription drugs?
Pregabalin can interact with other medications, increasing the risk of side effects like dizziness or drowsiness. Concerning interactions include those with opioids, which are pain-relieving medications, and benzodiazepines, which are used for anxiety or sleep disorders. These interactions can enhance sedative effects. Always inform your doctor about all medications you take to avoid harmful interactions and ensure safe treatment.
Can Pregabalin be taken safely while breastfeeding?
Pregabalin is not recommended while breastfeeding. Limited information is available on whether it passes into breast milk, but it may pose risks to the baby. If you're breastfeeding or planning to breastfeed, discuss safer medication options with your doctor. They can help you choose a treatment that allows you to nurse your baby safely.
Can Pregabalin be taken safely while pregnant?
Pregabalin is not recommended during pregnancy unless absolutely necessary. Limited evidence exists on its safety, and it may pose risks to the unborn baby. Animal studies suggest potential harm, but human data is lacking. If you're pregnant or planning to become pregnant, talk to your doctor about the safest treatment options for your condition.
Does Pregabalin have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Pregabalin include dizziness, drowsiness, and dry mouth. These occur in more than 10% of users. Serious side effects, like allergic reactions or mood changes, are rare but require immediate medical attention. If you notice any new or worsening symptoms, contact your doctor to discuss your treatment.
Does Pregabalin have any safety warnings?
Yes, Pregabalin has important safety warnings. It can cause dizziness and drowsiness, affecting your ability to drive or operate machinery. Pregabalin may also increase the risk of suicidal thoughts or behavior. If you experience mood changes or thoughts of self-harm, seek medical help immediately. Not adhering to these warnings can lead to serious consequences, so always follow your doctor's advice and report any concerning symptoms.
Is it safe to drink alcohol while taking Pregabalin?
It's best to avoid alcohol while taking Pregabalin. Alcohol can increase side effects like dizziness and drowsiness, which may impair your ability to perform tasks safely. If you choose to drink occasionally, limit your alcohol intake and be aware of any warning signs like increased dizziness or difficulty concentrating. Talk to your doctor about alcohol use while on Pregabalin for personalized advice.
Is it safe to exercise while taking Pregabalin?
You can exercise while taking Pregabalin, but be cautious. Pregabalin can cause dizziness or drowsiness, which might affect your balance or coordination during physical activity. To exercise safely, start with light activities and gradually increase intensity. Stay hydrated and listen to your body. If you feel dizzy or unusually tired, stop and rest. Consult your doctor if you have concerns about exercising while on Pregabalin.
Is it safe to stop Pregabalin?
Stopping Pregabalin suddenly can cause withdrawal symptoms like anxiety, insomnia, or nausea. It's usually used for long-term management of conditions like nerve pain or epilepsy. To stop safely, your doctor may suggest gradually reducing the dose. Always talk to your doctor before stopping Pregabalin to avoid worsening your condition or experiencing withdrawal symptoms.
Is Pregabalin addictive?
Pregabalin can be habit-forming for some people. It may cause physical dependence, especially if taken in higher doses or for a long time. Signs of dependence include cravings and withdrawal symptoms like anxiety or insomnia when stopping the medication. To prevent dependence, take Pregabalin exactly as prescribed and talk to your doctor if you have concerns about addiction.
Is Pregabalin safe for the elderly?
Elderly individuals are more vulnerable to the side effects of Pregabalin, such as dizziness and drowsiness, which can increase the risk of falls. Pregabalin is generally safe for the elderly when used with caution. Doctors may start with a lower dose and monitor for side effects. Regular check-ups help ensure the medication is safe and effective for older adults.
What are the most common side effects of Pregabalin?
Side effects are unwanted reactions to a medication. Common side effects of Pregabalin include dizziness, drowsiness, and dry mouth, affecting more than 10% of users. These side effects are usually mild and may improve as your body adjusts to the medication. If you experience new symptoms after starting Pregabalin, they might be temporary or unrelated. Talk to your doctor before stopping the medication.
Who should avoid taking Pregabalin?
Pregabalin should not be used if you are allergic to it or its ingredients. This is an absolute contraindication. Caution is needed if you have a history of substance abuse or certain medical conditions like kidney problems. These are relative contraindications, meaning Pregabalin may be used if benefits outweigh risks. Always discuss your medical history with your doctor before starting Pregabalin.
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