defnixa

Introduction to Defnixa

Defnixa is a medication primarily used to treat a condition known as Duchenne muscular dystrophy (DMD) in children aged 5 and older. This condition leads to muscle weakening, and Defnixa helps manage the symptoms by reducing inflammation and suppressing the immune system.

Composition of Defnixa

The active ingredient in Defnixa is Deflazacort. When taken, it converts into an active form that binds to the glucocorticoid receptor in cells, helping to reduce inflammation and suppress the immune response.

Uses of Defnixa

• Treatment of Duchenne muscular dystrophy (DMD) in children aged 5 and older.
• Helps reduce inflammation in the body.
• Suppresses the immune system to manage symptoms of DMD.

Side Effects of Defnixa

Common Side Effects:

• Weight gain
• Increased appetite
• Round face (Cushingoid appearance)
• Upper respiratory infections (common cold)
• Frequent urination
• Nose and throat inflammation
• Excessive hair growth
• Irritability

Serious Side Effects:

• Allergic reactions such as rash, itching, or swelling
• Severe dizziness
• Trouble breathing

Precautions of Defnixa

Defnixa should not be taken by individuals who are allergic to it or any of its ingredients. It should be used with caution during pregnancy and breastfeeding. Stopping Defnixa suddenly can lead to steroid withdrawal syndrome, which includes symptoms like loss of appetite, nausea, vomiting, tiredness, and headache.

How to Take Defnixa

• Take Defnixa once daily by mouth.
• The recommended dose is about 0.9 mg for each kilogram of body weight.
• It can be taken with or without food.
• Avoid taking it with grapefruit juice.

Conclusion of Defnixa

Defnixa is an important medication for managing Duchenne muscular dystrophy in children. By reducing inflammation and suppressing the immune system, it helps alleviate the symptoms associated with this condition. However, it is crucial to follow the prescribed dosage and take necessary precautions to avoid potential side effects.