Citaza Injection (AZACITIDINE)
What is Citaza injection?
Citaza injection is a chemotherapy drug used to treat certain types of bone marrow disorders and blood cancers, such as myelodysplastic syndromes (MDS). It works by slowing cancer cell growth and restoring normal blood cell production by modifying DNA in cells.
What is the usual dose of Citaza injection?
The usual dose for adults is 75 mg per square meter of body surface area, given as a subcutaneous or intravenous injection daily for 7 days, in a 28-day cycle. Dosing for children is uncommon and determined by the doctor.
How do I take Citaza injection?
Citaza injection is administered by a healthcare professional as an injection under the skin or into a vein. Follow your doctor’s instructions and attend regular treatment sessions as scheduled.
For how long do I take Citaza injection?
Citaza injection is a medication used to treat certain types of leukemia and a type of bone marrow disorder called myelodysplastic syndrome (MDS). It belongs to a class of drugs called epigenetic modifiers, which affect the way genes are expressed. Citaza injection is typically taken once daily for the first 14 days of a 28-day cycle. The number of cycles depends on how well the patient responds to the medication and any side effects they experience.
What is Citaza injection used for?
Citaza injection is used for treating myelodysplastic syndromes, chronic myelomonocytic leukemia (CMML), and certain acute leukemias. It helps improve blood counts, reduces the need for transfusions, and lowers the progression to severe leukemia.
How long does it take for Citaza injection to start working?
Citaza injection may take 2–6 months of regular treatment to show significant improvements in blood cell counts and overall response. Regular monitoring helps track the progress.
Is Citaza injection effective?
Yes, studies show that Citaza injection effectively improves survival, reduces transfusion needs, and slows disease progression in patients with certain blood and bone marrow cancers.
How does one know if Citaza injection is working?
Regular blood tests and bone marrow evaluations determine Citaza injection’s effectiveness. Improved blood counts, reduced symptoms, and stable or shrinking abnormal cell populations are indicators of success.
How does Citaza injection work?
Citaza injection incorporates into DNA and RNA within cells, altering their function. This disrupts cancer cell growth while promoting the maturation of normal blood cells, helping to restore bone marrow function.
Who should avoid taking Citaza injection?
Avoid Citaza injection if you are allergic to it or have advanced liver disease. Discuss your medical history with your doctor, including kidney problems or blood clotting disorders.
Can I take Citaza injection with vitamins or supplements?
While many vitamins and supplements are safe, some may interfere with treatment. Always inform your doctor about any supplements you are taking before starting Citaza injection therapy.
Can I take Citaza injection with other prescription drugs?
Citaza injection may interact with certain medications, such as anticoagulants or drugs that affect blood counts. Share your complete medication list with your doctor to avoid harmful interactions.
Can Citaza injection be taken safely while pregnant?
Citaza injection is not safe during pregnancy as it may harm the fetus. Women of childbearing age should use effective contraception during and after treatment as directed by their doctor.
Can Citaza injection be taken safely while breastfeeding?
Breastfeeding is not recommended while on Citaza injection due to the potential for harm to the baby. Discuss safe feeding options with your healthcare provider.
Is Citaza injection safe for the elderly?
Citaza injection is commonly used in elderly patients, but they should be monitored closely for side effects like low blood counts and organ function changes. Adjustments may be needed based on tolerance.
How should I store Citaza injection?
Citaza injection is stored and handled by healthcare providers. If required at home, keep it in the refrigerator (2–8°C) and protect it from light. Do not freeze or shake the medication.
Does Citaza injection make people tired or drowsy?
Fatigue is a common side effect, affecting up to 40% of patients. Rest and maintain a healthy routine to manage it. If fatigue becomes severe, inform your doctor for further evaluation.
Does Citaza injection cause stomach upset?
Yes, nausea and vomiting are frequent side effects, experienced by about 70% of patients. Anti-nausea medications can help, and taking small, bland meals may minimize discomfort.
Does Citaza injection affect sleep?
Sleep disturbances are not commonly linked to Citaza injection. However, if you experience insomnia or other issues, discuss them with your doctor to address possible underlying causes.
Does Citaza injection make it hard to think or concentrate?
Difficulty concentrating is uncommon with Citaza injection but may occur due to fatigue or low blood counts. If cognitive issues persist, inform your doctor for further assessment or supportive care.
Does Citaza injection affect mood?
Mood changes like mild anxiety or sadness may occur but are generally uncommon. Emotional support and counseling may help manage such effects. Notify your doctor if mood changes are significant.
Does Citaza injection interfere with sexual function?
Citaza injection doesn’t typically affect sexual function directly but may lower libido due to fatigue or overall health changes. Discuss concerns with your doctor for supportive management.
Does Citaza injection affect appetite?
Loss of appetite is common with Citaza injection, potentially affecting up to 25% of patients. Eat small, nutritious meals frequently and seek advice from a dietitian if appetite loss persists.
Does Citaza injection cause weight gain?
Weight gain is not a usual side effect of Citaza injection. Unexplained changes in weight should be reported to your doctor for proper evaluation and management.
Does Citaza injection cause headaches?
Headaches can occur with Citaza injection but are not frequent. Over-the-counter pain relievers may help, but consult your doctor if headaches persist or worsen.
Does Citaza injection limit driving?
Citaza injection itself doesn’t impair driving. However, fatigue or other side effects may affect your ability to drive safely. Avoid driving if you feel unwell and inform your doctor if symptoms are significant.
Is it safe to drink alcohol while taking Citaza injection?
Alcohol is best avoided during Citaza injection treatment as it may increase liver strain and worsen side effects like nausea. Consult your doctor for specific recommendations about alcohol use.
Is it safe to drink coffee or tea while taking Citaza injection?
Yes, coffee and tea are safe to drink with Citaza injection unless otherwise advised. However, limit caffeine intake if it worsens nausea or affects overall comfort during treatment.
Is it safe to exercise while taking Citaza injection?
Exercise is generally safe but should be light and adjusted to how you feel. Avoid strenuous activities if you're fatigued or have low blood counts. Always consult your doctor before starting a new exercise routine.
What are Citaza injection possible harms and risks?
Common side effects include nausea, fatigue, low blood counts, injection site reactions, and diarrhea. Serious risks include infections due to low immunity and kidney or liver dysfunction. Contact your doctor for severe or unusual symptoms.
.svg)
