What is the difference between Opiram and tramadol?

Is Opiram a muscle relaxant?

No. Opiram is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Opiram be used with Tizanidine?

Yes, Opiram can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can you get high by using Opiram?

No. Opiram is not known to cause high. It is a non-narcotic painkiller.

What is the difference between Opiram and naproxen?

Both Opiram and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Opiram.

Is Opiram a sulfa drug?

Opiram is a sulphur containing compound. Opiram can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Is Opiram a NSAID?

Yes. Opiram is a non-steroidal anti-inflammatory drug (NSAID).

What is the difference between Opiram and nimesulide?

Both Opiram and nimesulide are pain killers. However, Opiram is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

What is the difference between Opiram and ketoprofen?

Both Opiram and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Opiram. Ketoprofen gel also showed excellent tolerability.

Can Opiram be used along with paracetamol?

Yes. Paracetamol can be used with Opiram as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Opiram be used with methocarbamol?

Yes. Methocarbamol can be used with Opiram as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Opiram a narcotic?

No. Opiram is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Opiram be used along with dexamethasone?

No. Opiram should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

What is the difference between Opiram and meloxicam?

Both Opiram and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Opiram.

Why is beta cyclodextrin added to Opiram?

Yes. Opiram can be combined with beta-cyclodextrin. Research has shown that combining Opiram with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

What are the contraindications for Opiram?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Can Opiram be used in the treatment of allergy?

No. Opiram is not a drug to treat allergy. It is a pain killer.

Are there any alternatives of Opiram?

Yes. There are alternatives to Opiram. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Is Opiram a blood thinner?

No. Opiram is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can Opiram be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Opiram or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Opiram.

Can Opiram be used with Lisinopril?

No. Opiram should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Opiram.

Can I use Opiram for a migraine?

Opiram is not approved for the treatment of migraine. Research studies have shown that Opiram is effective in significantly decreasing the pain associated with migraine without aura.

Can I use Opiram if I have peptic ulcer disease?

No. Opiram is contraindicated in cases of active peptic ulcer disease. Opiram is known to cause gastric ulceration and bleeding.

Can I use Opiram if I am pregnant?

No. Opiram should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can Opiram lead to difficulty in conception?

Yes. Opiram can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can Opiram be used with calcium channel blocker?

Yes. Opiram can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Can I use Opiram if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can I use Opiram if I have a deranged renal function?

No. Opiram should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

What increases the chances of getting a gastric ulcer when I am already taking Opiram?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Opiram?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Are Opiram and aspirin same?

No. Opiram and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Can Opiram lead to skin reactions?

Yes. Opiram is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Can Opiram be used with warfarin?

No. Opiram should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.