What are the serious side effects of Pcom?

Can I use Pcom if I am a diabetic?

Pcom in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pcom so taking piroxicam can lead to increased risk of renal failure by many folds.

Can Pcom be used with methocarbamol?

Yes. Methocarbamol can be used with Pcom as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Pcom be used in hypertension?

No. Pcom is not a medication to control hypertension. It is important to note that Pcom decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pcom.

Can you get high by using Pcom?

No. Pcom is not known to cause high. It is a non-narcotic painkiller.

Can Pcom be used along with dexamethasone?

No. Pcom should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

What is the difference between Pcom and nimesulide?

Both Pcom and nimesulide are pain killers. However, Pcom is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Are Pcom and aspirin same?

No. Pcom and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Can I use Pcom if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can Pcom be used in the treatment of allergy?

No. Pcom is not a drug to treat allergy. It is a pain killer.

Can I use Pcom if I have peptic ulcer disease?

No. Pcom is contraindicated in cases of active peptic ulcer disease. Pcom is known to cause gastric ulceration and bleeding.

Is Pcom affective in gout management?

Yes. Pcom can be given for the treatment of acute gout. Research studies have shown Pcom to be highly effective in the treatment of acute gout.

Can I use Pcom if I am pregnant?

No. Pcom should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

What is the difference between Pcom and tramadol?

Pcom is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Can I use Pcom for a migraine?

Pcom is not approved for the treatment of migraine. Research studies have shown that Pcom is effective in significantly decreasing the pain associated with migraine without aura.

How long does Pcom work?

Pcom is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can Pcom be used to treat menstrual cramp?

Pcom is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

What is the difference between Pcom and ketoprofen?

Both Pcom and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pcom. Ketoprofen gel also showed excellent tolerability.

What are the contraindications for Pcom?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Can Pcom lead to skin reactions?

Yes. Pcom is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Is Pcom a blood thinner?

No. Pcom is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can Pcom be used with Tizanidine?

Yes, Pcom can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Why is beta cyclodextrin added to Pcom?

Yes. Pcom can be combined with beta-cyclodextrin. Research has shown that combining Pcom with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can Pcom be used along with paracetamol?

Yes. Paracetamol can be used with Pcom as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Pcom a muscle relaxant?

No. Pcom is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Is Pcom a NSAID?

Yes. Pcom is a non-steroidal anti-inflammatory drug (NSAID).

Can Pcom lead to difficulty in conception?

Yes. Pcom can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pcom?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Pcom be used with calcium channel blocker?

Yes. Pcom can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Can Pcom be used with warfarin?

No. Pcom should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

What is the difference between Pcom and diclofenac?

Both Pcom and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Pcom.

Are there any alternatives of Pcom?

Yes. There are alternatives to Pcom. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Can I use Pcom if I have a deranged renal function?

No. Pcom should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

Can Pcom be used along with Losartan?

No. Pcom should not be combined with Losartan. It is important to note that Pcom decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pcom.