What are the serious side effects of Doloset?

Can I use Doloset if I have peptic ulcer disease?

No. Doloset is contraindicated in cases of active peptic ulcer disease. Doloset is known to cause gastric ulceration and bleeding.

Is Doloset a muscle relaxant?

No. Doloset is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Doloset be used with warfarin?

No. Doloset should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Are Doloset and aspirin same?

No. Doloset and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Is Doloset a blood thinner?

No. Doloset is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Is Doloset a NSAID?

Yes. Doloset is a non-steroidal anti-inflammatory drug (NSAID).

Can I use Doloset if I have a deranged renal function?

No. Doloset should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

What is the difference between Doloset and tramadol?

Doloset is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Can Doloset be used with diuretics?

No. Doloset should not be used with diuretics. Doloset reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Can Doloset lead to skin reactions?

Yes. Doloset is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Is Doloset affective in gout management?

Yes. Doloset can be given for the treatment of acute gout. Research studies have shown Doloset to be highly effective in the treatment of acute gout.

Can I use Doloset if I am pregnant?

No. Doloset should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can I use Doloset if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

What is the difference between Doloset and ketoprofen?

Both Doloset and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Doloset. Ketoprofen gel also showed excellent tolerability.

Can Doloset be used along with dexamethasone?

No. Doloset should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

What is the difference between Doloset and naproxen?

Both Doloset and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Doloset.

Is Doloset a narcotic?

No. Doloset is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Doloset be used to treat menstrual cramp?

Doloset is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Can Doloset be used in the treatment of allergy?

No. Doloset is not a drug to treat allergy. It is a pain killer.

Is Doloset a sulfa drug?

Doloset is a sulphur containing compound. Doloset can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Can Doloset be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Doloset or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Doloset.

Can Doloset be used with methocarbamol?

Yes. Methocarbamol can be used with Doloset as no serious side effects are known. Inform your doctor before starting any of the medication.

What increases the chances of getting a gastric ulcer when I am already taking Doloset?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

What is the difference between Doloset and meloxicam?

Both Doloset and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Doloset.

Can Doloset be used in hypertension?

No. Doloset is not a medication to control hypertension. It is important to note that Doloset decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Doloset.

Is Doloset effective in back pain management?

Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Doloset as the cause of back pain can be different for different person.

What are the contraindications for Doloset?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Are there any alternatives of Doloset?

Yes. There are alternatives to Doloset. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

How long does Doloset work?

Doloset is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can Doloset be used with Tizanidine?

Yes, Doloset can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Why is beta cyclodextrin added to Doloset?

Yes. Doloset can be combined with beta-cyclodextrin. Research has shown that combining Doloset with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can I use Doloset for a migraine?

Doloset is not approved for the treatment of migraine. Research studies have shown that Doloset is effective in significantly decreasing the pain associated with migraine without aura.

Can you get high by using Doloset?

No. Doloset is not known to cause high. It is a non-narcotic painkiller.

Can Doloset be used with Lisinopril?

No. Doloset should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloset.